Rolfe said:
Do it tomorrow, honest injun.
I'll have to bail till tomorrow. I've got some actual work that needs doing.
However, there's a point that's becoming increasingly obvious. Hans' stipulation that the mother tincture should be 1M is impossible. 1M is 1g molecular weight/litre. No big deal with small molecular weight salts (like KCN, MW 93 daltons, so a molar solution is 93g/l) and things like that, but entirely impractical with macromolecules such as ricin (MW 64,000 daltons) or botulinum toxin (A chain molecular weight 50,000 daltons, and the B chain is actually 100,000 daltons). This would require many kg of pure toxin to be dissolved in a litre of water, which is obviously completely impractical.
We really need to go gravimetric at the start, and to estimate the concentration of the mother tincture in g/l. I really have no idea at all what the actual mother tinctures as used by homoeopaths contain. The only concrete information we have is that 250µg of LSD was used to prepare the original LSD mother tincture (volume of solution prepared not stated). And we know that the mother tinctures of plant remedies sold by Helios came as little 5ml bottles with presumably again only mg or maybe µg of "dry matter".
Anybody got any recommendations as to what gravimetric concentration we should shoot for, for the hypothetical mother tinctures? 1g/l? 10g/l? 100g/l? That last is top whack I think, even for a hypothetical exercise, and I suspect that the real mother tinctures are a lot lower.
Of course this means that different substances will hit Avogadro's limit at slightly different stages. The high molecular weight compounds will have many fewer molecules in a gramme than the salts. And with salts that dissociate, are you interested in all the ions, or just one? Do you count the K<SUP>+</SUP> in KCN? Or are you just interested in the poisonous CN<SUP>-</SUP> ion? However, these are easy enough to allow for once the ground rules are set. It's just that the ground rule obviously can't be a 1M solution of everything.
Ashles said:
"sympathetic BA staff" -
Rolfe, I suddenly find myself unable to believe a word you write - you seem to be describing the most elusive of mythical creatures here.
It really did happen. I suspect that it wasn't a busy time, the flights involved weren't full, and that the presence of a little old lady of 88, with a walking stick and poor eyesight, rather confused at the airport because her oh-so-brilliant, Internet-savvy daughter had completely screwed up her online booking, brought out the mother-hen instinct.
Anyway, they really were very helpful, sorted outn the booking to what it was supposed to be without extra charge, then shunted Mum on to the later flight because the mixup had taken too much time, and fed her tea and sandwiches in the Executive Club lounge until the 2.15 departure.
The age of miracles is not yet over.
Rolfe.
(And BA once was remarkably compliant with me when I messed up a flight to Jersey, and let me go to Guernsey instead on a completely different flight at no extra charge when it transpired that there were simply no Jersey seats to be had. So all I had to do was get a short island-hop flight, rather than be stuck at Gatwick over Easter weekend. So there, they're not so bad!)