Study quashes vaccine anxiety

It's the genetics of the disease. You won't find a simple statement just saying "all kids with these genes have the disease". The literature presents the genetics and how it affects people with it. It thus shows that it's impossible to not to get the disease with those genes. I'd have to quote the entire articles, which I don't even think is allowed. Please show how the people with those genes could possibly escape the disease. It would be like trying to show how people with the blue eyed genes could escape getting blue eyes, or the people people with hazel eyed genes would somehow get brown, It's impossible not to get what your gene combinations contain.
Eos, no. It is not "impossible not to get what your gene combinations contain." It depends entirely on what you are talking about. In some cases yes, but in other cases definitely no.

Example. I spent some time in the 1990s researching a condition in Irish Wolfhounds, congenital portocaval shunt. I didn't look at the genetics myself, because I'm a biochemist not a molecular biologist, I was evaluating a practical test for the condition which would allow breeders to identify affected puppies before they were sold. The breeders kept asking me how it was inherited, so I tried to keep up with the literature on that. At first nobody thought it was a simple Mendelian recessive, because the numbers affected were way below the 25% of a litter that would be expected to have the double recessive if two carriers were mated. However, that's what it turned out to be. Every puppy with the condition has the double recessive, and no puppy without the double recessive has the condition. It's just that less than 50% of puppies with the double recessive develop the condition. So far as I know, nobody has yet figured out what else needs to happen to a puppy with the double recessive to make it develop the shunt.

Here we have a condition which (as I read the papers you posted) has a more complex, multi-gene causation. Also, the clinical condition is alleged to be triggered by a fever. So, I ask myself, is it possible that the condition may never be triggered in some genetically susceptible individuals? It seems a reasonable hypothesis that no child can get through childhood without such a fever, and indeed unvaccinated children may be more prone to fevers than vaccinated. Nevertheless, I would like to know. I really can't see that information anywhere.
The literature presents the genetics and how it affects people with it. It thus shows that it's impossible to not to get the disease with those genes.
I did see the first in the papers you linked to. I did not see any implication of the second. I wonder if you are reading more into the text than is actually there.

I'll leave Raven to the tender mercies of you guys, as it seems that some genuinely antivax sentiment is being revealed.

However, my curiosity as regards his initial post was twofold. First, what description of the sort of seizures that may be caused by pertussis is he relying on to conclude that his son's seizures were of that type? Second, what was the opinion of his son's doctor or paediatrician about the episode? Did he or she agree that the vaccine was probably responsible?

There are some (relatively rare) cases of adverse reactions to vaccines. And if such a reaction is supected then it may indeed be wise advice that that child should not receive any further doses, but should instead rely on herd immunity. The fallacy that has to be avoided at this point it to then go on and undermine herd immunity by suggesting widespread non-vaccination just because of the extreme reaction of a single individual. Counter-productive, or what?

Rolfe.
 
...I've also spent a great deal of time on farms, and if the animals are well cared/clean/fed, rampant illness is rarely a problem. Actually, it's the cheap farmers who DO vaccinate, ime, since it is much cheaper than providing adequate conditions for their animals.
Welcome Raven.

I agree that in some situations vaccination can be used as a substitute for sub-optimal management practices, particularly against pneumonia and some enteric infections although whan combined with improvement in management vaccines can be helpful in such conditions.

In many cases though, particularly with clostridial infections the level of disease has little or nothing to do with hygiene or levels of nutrition; infact many clostridial diseases in sheep affect the best fed and fastest growing lambs. Leptospirosis is another example, possibly more important as it can transmit to people.

Vaccination is the only means of control for these sometimes "rampant" diseases.

Yuri

PS can I add my two-pence worth to Rolfe's comments and request Raven is cut some slack; enough with the superior airs and condescension please.
 
... oh, and Skeptigirl, please keep on translating acronyms. Raven may understand them but I'm happy to admit I sometimes don't. When Eos said he had "hazel eyes (BH)" I thought it was email speak for saying "BooHoo" 'cos he didn't have blue eyes (Jeez!) - I got it eventually, some of the best things take time.

Yuri
 
Welcome Raven.

Vaccination is the only means of control for these sometimes "rampant" diseases.

Yuri

PS can I add my two-pence worth to Rolfe's comments and request Raven is cut some slack; enough with the superior airs and condescension please.

Hmmm, just try posting that rather non-immflammatory wording in the beginning of the quote to that mothering site Raven came from.

I'm suspecting the folks posting with the perceived "superior airs and condescension" have had the most experience with the anti-vax crowd's own superior airs and condescension. From seeing it all before and dealing with it all before, you yourself will see the exchanges with Raven coming to the inevitable tromping off without citing sources. WE vaxxers are close minded, brainwashed baffoons for not listening to likes of mercola. Our cited sources are merely puppets for "big pharma".

Have you noted that arrogant claims that vaccination is just an excuse to not take care of something adequately? Have you not seen that we are not educated on this matter? Have you noticed the lack of citing? You will learn that internet and the likes of scheibner will be seen as far more credible than diry ol' allopathy and closeminded science.
 
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... oh, and Skeptigirl, please keep on translating acronyms. Raven may understand them but I'm happy to admit I sometimes don't. When Eos said he had "hazel eyes (BH)" I thought it was email speak for saying "BooHoo" 'cos he didn't have blue eyes (Jeez!) - I got it eventually, some of the best things take time.

Yuri


Sorry, I didn't mention Mendelian genetics...I'll try to find something that makes sense on the net...

http://anthro.palomar.edu/mendel/mendel_2.htm

My watered down example was Heterozygous vs Monozygous, with the combinations having obvious outcomes.
 
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A little on epilepsy and genetics...
http://www.epilepsy.com/articles/ar_1064855875.html
How is microarray-based research likely to contribute to therapeutic advances in epilepsy?
The primary application of DNA microarrays in epilepsy research is to evaluate changes in gene expression that are associated with epilepsy. Using experimental epilepsy models in which epilepsy is induced in animals, two kinds of studies are being performed using DNA microarray technologies:
Broad-scale analysis of gene expression in brain regions that undergo significant structural changes during the development of epilepsy. Researchers hope to identify specific genes that contribute to changes in the brain that may cause seizures when they are inappropriately turned on or off.
Characterization of the expression of specific gene families within individual cells located in a region of the brain often involved in recurrent seizures. By combining this analysis with studies of the electrical properties of the cell, researchers hope to determine how gene expression may underlie cellular hyperexcitability that contributes to the development of epilepsy.

http://www.feinberg.northwestern.edu/igp/facindex/HerzingL.html
My laboratory focuses on gene expression, and how misregulation of expression, rather than gene mutation, can contribute to disorders including autism, epilepsy, and Rett syndrome. Our goals are to identify genes that are inappropriately expressed, either in amount, location or developmental timeframe within neurodevelopmental disorders. This will allow us to directly characterize the consequences of misexpression at the cellular and organismal level, and will highlight pathways critical to the development of these disorders that may be impaired in other individuals, leading to the identification of additional genetic defects, and to novel or more specific treatment options.

http://www.epilepsyfoundation.org/epilepsyusa/researchprojects.cfm
Identifying a gene associated with epilepsy aids in determining who may be at risk for having epilepsy.
Last year, a researcher funded through the Foundation’s research program identified specific factors that predict when febrile (fever-related) seizures and epilepsy within the same person and within families. This information may help in identifying who may be at risk for epilepsy, febrile seizures or both. This research will also help find the genes that increase the risk for epilepsy or febrile seizures and aid in genetic studies.
Another way genetics is used to help in studying epilepsy, is by looking at the chemicals produced by a gene. When a gene is turned on or “expressed”, it produces a chemical message. The ability to detect this chemical message is achieved through gene expression technology. This technology is being used to study how epilepsy and many other disorders occur. The idea is to identify the proteins (DNA encoded proteins) in the brain that are present where the seizure begins (epileptic foci) and to compare those areas to areas where seizures are absent. A scientist funded through the research program has identified some of these molecules. This important discovery will provide further insights into how seizures develop. And, in the future, may lead to more effective treatment

From what I understand, "genetic predispositions" are sort of a spectrum of coorelation, with "association" on one end and "absolute causation" on the other.
So, the Dravats gene might very well be one of the "absolute causation" ones, but we don't know right now.

Rolfe said:
There are some (relatively rare) cases of adverse reactions to vaccines. And if such a reaction is supected then it may indeed be wise advice that that child should not receive any further doses, but should instead rely on herd immunity. The fallacy that has to be avoided at this point it to then go on and undermine herd immunity by suggesting widespread non-vaccination just because of the extreme reaction of a single individual. Counter-productive, or what?
I agree.

While we're off in the no man's land of general vaccination debate, I was wondering if someone who perhaps understands bacteriology better than I do could explain what's going on with this...is it coincidence, or is there a "floral balance" factor at play, or something else I'm missing entirely...





http://jcm.asm.org/cgi/content/full/42/2/807

The aim of this study was to compare the phenotypes and genotypes of H. influenzae strains isolated from patients with invasive disease, according to the time of isolation, i.e., before the use of the Hib vaccine (1989 to 1993), during the period in which the vaccine was optional (1994 to 1999), and after the vaccine was included in the National Vaccination Plan (2000 to 2001).

We show that the introduction of the vaccine in Portugal led to changes in H. influenzae, particularly the decline in strains of serotype b (from 81 to 16%), which was accompanied by a relative increase of NC strains (from 19 to 80%). We also report for the first time a Portuguese serotype f invasive strain that was isolated during the vaccination period. The efficacy of the Hib conjugate vaccine (10) has been extensively studied, and it significantly reduces the incidence of carriage in immunized children, which may have several consequences, e.g., the isolation of other serotypes in cases of invasive disease, especially serotypes a and f (18, 19); an increase in virulence of non-b serotypes (15, 16); and a concomitant increase in NC strains (9).



So after implementing vaccination we went from 81 to 16% for the Hib strains there's a vax for, (which is shows that the vaccine was doing one of the things it was intended to do) but from 19 to 80 for the ones we don't.(which looks like an unexpected negative effect).


Surveillance of H. influenzae isolated from cases of invasive disease will be required to monitor developments concerning this pathogen, as it is likely that non-serotype-b encapsulated H. influenzae or NC strains will emerge as vaccination becomes prevalent worldwide.


One hundred nineteen strains of H. influenzae, isolated between January 1989 and December 2001 from patients with invasive infections (52 from cerebral spinal fluid, 63 from blood, 4 from pleural fluid) at 16 hospitals in Portugal and sent to the Antibiotic Resistance Unit at the National Institute of Health in Lisbon, were included in this study
...just in case anyone was wondering if this increase was only involving harmless gut flora.
Nope...we're talking septemia and bacterial meningitis here.


And the same phenomenon being quietly watched in Africa with the n.meningitidis bacteria…
http://www.cdc.gov/ncidod/EID/vol8no3/01-0308.htm#Table
http://www.cdc.gov/ncidod/EID/vol8no3/01-0308.htm
 
A little on epilepsy and genetics...
...snippy.. snip...

From what I understand, "genetic predispositions" are sort of a spectrum of coorelation, with "association" on one end and "absolute causation" on the other....

That may be the case with my son. My hubby's family has a history of migraines. His father and a grandmother were plagued by migraines, and one of his relatives has had chronic migraines for at least 20 years (of the type described in All in My Head). Also in Oliver Sacks' book Migraine, there are sometimes blurred lines between migraines and seizures.

Also, let us not forget that the infections can also be causes of seizures. I know of one child my son's age who almost died from Hib as a toddler, and the seizures he had gave him a similer disorder as my son (with a few other added things, like Tourette like characteristics). Also, my son's last seizure was when he was dehydrated from a bout of a gastrointestinal bug that may or may not be the type now preventable with the rotavirus vaccine. Oh, and one of the complications of pertussis the actual disease are seizures.
 
The stuff about the epilepsy/migraine connection is really interesting.
(I have had both, so it's a subject of interest to me).

I'll find the link on this if you're interested, HC...but this is crazy, what I stumbled across earlier looking up those links...
There's a journal of neurology paper where they found that sometimes a "statis seizure" can be the thing that causes the change in gene expression that makes some people inclined to have further seizures.
I always thought it was probably some kind of small structural damage or something like that (or the formation of deep neural pathways from a statis?) that was the only factor behind the "seizures beget seizures" rule.
Anyway, let me know if you want me to try to re-find it again. :)
 
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...Anyway, let me know if you want me to try to re-find it again. :)

Ooh... that would be cool! (we should probably start a new thread on migraines and seizures)

Not that we have to worry much anymore. Son started to get migraines at the end of 8th grade. Then at the beginning of 9th grade he was diagnosed with a genetic heart condition (from my side of the family!)... so he takes beta blockers, which now mostly keep the migraines away. (one reason why I know about both the www.efa.org and www.4hcm.org websites!)
 
Flange “overstated” to the point of distorting the conclusions of the study cited, as did the author of the article he/she linked to, not “a little”.
That constitutes a significant breach of critical thinking, imo, so I mentioned it.

Welcome Raven.

As you can see, I used the newspaper headline as the thread title.
Yes it is true that the newspapers often overstate things.
Critical thinkers can usually see past these overblown newspaper headlines, so there is no need to attack the messenger.

You have prompted some great discussions. For this: Brava!
 
Ooh... that would be cool! (we should probably start a new thread on migraines and seizures)

Not that we have to worry much anymore. Son started to get migraines at the end of 8th grade. Then at the beginning of 9th grade he was diagnosed with a genetic heart condition (from my side of the family!)... so he takes beta blockers, which now mostly keep the migraines away. (one reason why I know about both the www.efa.org and www.4hcm.org websites!)


I couldn’t find the one I read at first, but I found another one.
http://www.ncbi.nlm.nih.gov/entrez/...uids=15217381&query_hl=16&itool=pubmed_docsum

Epileptogenesis produced marked changes in expression of 27 of 1090 genes.


And this one is just interesting, in a weird way…I read one similar to it a while back called, I think, “signs of paranoia in rats with temporal lobe epilepsy”.
(and yes, haha…it is funny that an epileptic is posting this in this context…if you can’t laugh at yourself, etc.)
http://www.ncbi.nlm.nih.gov/entrez/...uids=16324784&query_hl=24&itool=pubmed_docsum
That one also mentions epileptogenesis causing a change in gene expression, and ties it in with “kindling theory”.
 
A person who completely ignores their own experience in favor of statistical or other abstract evidence which appears to contradict it is as big an idiot as one who completely ignores any evidence which appears to contradict their own experience, imo.

And yet it was people ignoreing their own experence that allowed them to come up with the sol centered model of the solar system

True critical thinking requires a balance between the two.

I'm sorry but Tychonic model of the solar system is incorrect.
 
Hydrogen Cyanide,

First, I know use to quote button, I just don’t prefer it, finding it more cumbersome than a more straightforward method. I apologize if this bothers you, but using the quote function really bothers ME, so I don’t.
I use ***s to enclosed quotations from YOU in my replies to YOU. ( I do my best to personally respond individually to others, not lump everyone into one post, so if you see a post with your name at the top, assume every passage with *** bracketing it is something YOU said, to which I am responding.)

***My son did not get pertussis (though he was hospitalized 4 times with croup)... but that was because we were very careful. You were probably protected by herd immunity. Many kids were not.***

Sorry to hear it. I sort of doubt herd immunity had much to do with it in our case, since we lived and circulated in a setting in which the pertussis vaccination rates were rather lower than average.

***It is often fatal to children under the age of one. So I was exaggerating with the "usually fatal".**

You are still exaggerating; a mortality rate of 1% to 2% in no way justifies the term “often”.
“Rarely” or “occasionally” would be more accurate terms.
FTM, the highest risk, represented by the up to 2% figure, are found in those under 6 months and the risks decline dramatically afterwards.

***Now give me the statistics that show the DTaP (DTP is now no longer used) is more dangerous than the actual disease for a child under the age of one year. You note that the mortality rate is less than 2%***

Did I ever claim that? Nope. So why do you now demand I produce evidence of it?
Really, could y’all please try to differentiate between my actual comments and what you assume I SHOULD say, based on pre-existing stereotypes of what an “anti-vaxer” is? FTM, I have never given an indication that I AM an “anti-vaxer”, only that I am a NON-vaxer. Much has been read into my comments which is not justified, imo.

***What kind of wonderful odds are those?... so are you saying that that complication rate with the vaccine is more than that! What is it, 3%, 5% or even 10%?***

The complication rate with the vaccine was 100% in MY SON, as it turned out. And, as it turned out, his complication rate from the illness was 0. I am, again, NOT saying the risk of the vaccine OVERALL, for EVERY child, is higher than the risks of the illness, but in certain cases, YES, the risks of the vaccine must be carefully balanced against those of the illness. Even the CDC and the manufacturer say this. Why is it taken to be some kind of radical position?

**I think that making sure that the child avoids the disease through vaccination is a better bet than hoping that he/she does not get from someone else.
But that is what you are doing, playing the odds with not only your kid's health, but other people too.***

If the child appears to tolerate the vaccine without extreme reactions, as most appear to do, your approach may indeed be best. If not, your approach constitutes “playing the odds” with my (or your, if yours was the one who reacted severely) “kid’s health”, something I am NOT willing to do, or even ask YOU to do, even IF it might benefit “other people”, even myself.

My children (or yours) are not sacrificial lambs to society. If you find that concept offensive, that is your prerogative, as it is mine to find the concept of individuals being compelled to assume serious risks against their will/better judgment on behalf of themselves or their children in the name of the “greater good” offensive. Just not into the whole tossing virgins into the volcano scene, myself. There are, imo, certain inalienable rights in a civilized society, including the right to decide what, if anything, is injected into your body or that of your children, esp. when the substance injected has the potential to maim or kill. I will stand up for your rights in this respect as vigorously as I will mine. JMHO.

Besides, let’s be real here. The primary risk of exposure to pertussis for infants is NOT from unvaccinated or even under vaccinated infants or young children. It is from FULLY vaccinated teens and adults whose immunity has waned. FTM, some studies have shown a significant risk from fully vaccinated PRESCHOOL children, who are capable of contracting sub clinical cases and transmitting them to others.

The reasons for the current rise in pertussis are pretty clear, despite the CDC and some others claiming to be “baffled” by it, in light of all-time high levels of vaccination. It is simply difficult and unpolitic for them to admit that this is a classic case of an epidemiological shift under the pressure of mass vaccination.
But the evidence is pretty clear, so clear that the working solution is a booster dose for teens and adults to try and remedy the problem of waning vaccine immunity.

Forgive me for quoting your response to someone else, but I feel the need to address this:

***Because one out of a thousand or ten thousand reaction does occur, that does not mean all vaccines are dangerous.***

I repeat, I NEVER sated OR implied any such thing. WHY does it seem several here have leapt to the conclusion that such is my position based on my pointing out what I considered to be an erroneous assumption re’ ONE vaccine and RARE events which may be associated with it? Hardly the same as adopting the position that ALL vaccines are “inherently dangerous” for ALL people. JFTR.

Raven
 
... oh, and Skeptigirl, please keep on translating acronyms. Raven may understand them but I'm happy to admit I sometimes don't. When Eos said he had "hazel eyes (BH)" I thought it was email speak for saying "BooHoo" 'cos he didn't have blue eyes (Jeez!) - I got it eventually, some of the best things take time.

Yuri
Just ask, I do. It isn't unusual to not know them all. I work with several different businesses and settings. They all have their own and they aren't the same. Psych uses different ones that the Fire Departments for example. Anyway..

ACIP Advisory Committee for Immunization Practices
CDC Center for Disease Control
VZV Varicella Zoster Virus -- virus that causes chicken pox and shingles
VZIG Varicella Zoster Immune Globulin -- like gamma globulin but specific for chicken pox or shingles
DPT Diphtheria Pertussis Tetanus
DT Diphtheria Tetanus
OTOH on the other hand
BTW by the way
vs verses
WHO World Health Organization

Don't know if I missed any others.

Raven used CP for chicken pox and wrt which I don't know if it was an acronym or a typo

I wore myself out and gave up on that post. After a while there was just too much to refute. The amount of incorrect information on the diseases was extensive. Then I saw others had covered much of it already.
 
Hmmm, just try posting that rather non-immflammatory wording in the beginning of the quote to that mothering site Raven came from.
My point exactly, why should we treat 'dissentors' on this list the same way?

I'm suspecting the folks posting with the perceived "superior airs and condescension" have had the most experience with the anti-vax crowd's own superior airs and condescension. From seeing it all before and dealing with it all before, you yourself will see the exchanges with Raven coming to the inevitable tromping off without citing sources.

I'm not unfamiliar with such debates myself on other lists and on a one to one level and I freely admit that on occasions I have got carried away, hot under the collar and used intemporate language myself but I have usually regretted it both from a personal point-of-view as being plain rude and more importantly because it gets the debate nowhere. If you insult someone just because they disagree with you all you're going to do is make them dig their heels in further & confirm their prejudices about "closed minded sceptics".

Yuri
 
Raven 1, the reason I conclude you are against all vaccines for all people is because you have posted that you thought vaccines were pushed with fear campaigns, that you read whatever and chose not to vaccinate you child after 1 or? dose(s). Have you posted anything supporting the use of vaccines?

But it wouldn't matter. Most of the posts refute very specific statements you have made. Your beliefs about who is at risk and which age groups get this or that and the nonsense that we hear all time that somehow deadly diseases offer better protection than vaccines (against those same deadly diseases) are based on bad facts. As an infectious disease specialist I can say with total confidence you don't know what you are talking about. Just get a good book on infectious diseases and read it. Or at least stop spreading your misinformation around without a little fact checking. What a shame that you would give your unqualified inaccurate opinions to some person who might not vaccinate their children.

You are still exaggerating; a mortality rate of 1% to 2% in no way justifies the term “often”.
“Rarely” or “occasionally” would be more accurate terms.
FTM, the highest risk, represented by the up to 2% figure, are found in those under 6 months and the risks decline dramatically afterwards.
And you cannot justify why the safer option of a vaccine with a lower risk should not be used for everyone it is clinically indicated for. (In other words, what the ACIP recommends.)

The complication rate with the vaccine was 100% in MY SON, as it turned out. And, as it turned out, his complication rate from the illness was 0. I am, again, NOT saying the risk of the vaccine OVERALL, for EVERY child, is higher than the risks of the illness, but in certain cases, YES, the risks of the vaccine must be carefully balanced against those of the illness. Even the CDC and the manufacturer say this. Why is it taken to be some kind of radical position?
That part isn't. It's the next part, that somehow if a child reacts to one vaccine all vaccines are bad for that child. And the part after that. All the inaccurate beliefs you posted that you have about these infections. And the nonsensical assumption that diseases are better because they provide better immunity from those diseases. That's nuts. If the diseases are not bad, who cares about providing immunity? The diseases are bad, there is no advantage in allowing your child to have these infections at a particular age. There is no safe age to get any of these vaccine preventable diseases.

if the child appears to tolerate the vaccine without extreme reactions, as most appear to do, your approach may indeed be best. If not, your approach constitutes “playing the odds” with my (or your, if yours was the one who reacted severely) “kid’s health”, something I am NOT willing to do, or even ask YOU to do, even IF it might benefit “other people”, even myself.
The problem with what you say here is that when a child reacts to a single vaccine, it isn't recommended that they get more doses. You act as if someone wanted to give your child doses of vaccine that the child may have reacted to.

OTOH, if your child reacted to a DPT and you decided to not give any vaccines, that would be the fear reaction you claim everyone else is being subjected to. It is you who have an unwarranted fear of vaccines, not the public that has an unwarranted fear of certain infections.

My children (or yours) are not sacrificial lambs to society. If you find that concept offensive, that is your prerogative, as it is mine to find the concept of individuals being compelled to assume serious risks against their will/better judgment on behalf of themselves or their children in the name of the “greater good” offensive. Just not into the whole tossing virgins into the volcano scene, myself. There are, imo, certain inalienable rights in a civilized society, including the right to decide what, if anything, is injected into your body or that of your children, esp. when the substance injected has the potential to maim or kill. I will stand up for your rights in this respect as vigorously as I will mine. JMHO.
As if the diseases didn't maim or kill.

Why, if the vaccines prevented disease, would the kids who the government recommended the vaccines to be "sacrificed for society"? And if the vaccines didn't work, why would the government want to sacrifice the kids by using the vaccines? Your logic isn't logical.

Besides, let’s be real here. The primary risk of exposure to pertussis for infants is NOT from unvaccinated or even under vaccinated infants or young children. It is from FULLY vaccinated teens and adults whose immunity has waned. FTM, some studies have shown a significant risk from fully vaccinated PRESCHOOL children, who are capable of contracting sub clinical cases and transmitting them to others.
Well duh! Because those other kids are vaccinated!!! If they weren't then the risk would be from all kids not just the ones we couldn't (until recently) vaccinate.

The reasons for the current rise in pertussis are pretty clear, despite the CDC and some others claiming to be “baffled” by it, in light of all-time high levels of vaccination. It is simply difficult and unpolitic for them to admit that this is a classic case of an epidemiological shift under the pressure of mass vaccination.
But the evidence is pretty clear, so clear that the working solution is a booster dose for teens and adults to try and remedy the problem of waning vaccine immunity.
I'm not sure why you think no one at CDC knew this. Perhaps you misunderstood some popular article because CDC has been well aware of it for a decade or more. In fact, now that I think about it, I've known about it since at least 1985 when a physician friend of mine came down with Pertussis. We were also able to manage those exposed and no additional cases occurred directly from exposure to him.

Yes, the Pertussis vaccine successfully protected the youngest members of society, the ones at most risk. Yes, the infection epidemiology shifted to an older age group. If we were only able to do that we still would be preventing a lot of deaths with the vaccine. But not all kids were protected. Now we have a vaccine booster for teens and adults. We can protect more children. Why would we not want to do that?
 
Thanks for that expert view, Skeptigirl. One of your points needs saying again, with emphasis:
If childhood diseases are so benign, and catching them actually makes children healthier, WHY THE (RULE 8) WERE VACCINES DEVELOPED IN THE FIRST PLACE???

Thank you for reading.
 
Hydrogen Cyanide,

First, I know use to quote button, I just don’t prefer it, finding it more cumbersome than a more straightforward method. I apologize if this bothers you, but using the quote function really bothers ME, so I don’t.
I use ***s to enclosed quotations from YOU in my replies to YOU. ...

It is not that hard to type in "[/quote]" or to cut and paste the first part. I actually think you are purposely trying to make your posts hard to read and follow.
 
Thanks for that expert view, Skeptigirl. One of your points needs saying again, with emphasis:
If childhood diseases are so benign, and catching them actually makes children healthier, WHY THE (RULE 8) WERE VACCINES DEVELOPED IN THE FIRST PLACE???

Thank you for reading.

I can give the standard "John Scudamore" answer (owner of oft used Whale.to website with all sorts of scaremongering articles): "To create profits for Big Pharma. The vaccines are made by Big Pharma to make people sicker so that they can buy more drugs from Big Pharma. Which is all part of the Tri-Lateral Commission and the Illuminati to control the world".
 
....The vaccines are made by Big Pharma to make people sicker so that they can buy more drugs from Big Pharma. Which is all part of the Tri-Lateral Commission and the Illuminati to control the world".
Whoa! And here with my Master's degree and 30 years of practice (pay no attention to how old that makes me, school and practice did overlap), my insatiable appetite to read and explore everything, my concern about how corporate profit motives and political influence do indeed impact society, and my US and world travels I missed that! Oh my!

And BTW, not using the quote command indeed makes it harder to follow posts. Guess that goes with how dumb I am in general.
 
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