Covid-19 cases are starting to rise again as a result of the JN.1 Covid variant, which appeared last September in France. The variant accounts for around 60% of new infections in early January, according to a data tracker from the US Centers for Disease Control and Prevention (CDC).
At the same time, data from both the CDC and the UK Health Security Agency shows that hospitalisations and deaths from Covid-19 are markedly lower compared to January 2023. Primary care physicians say they are finding it virtually impossible to distinguish Covid-19 symptoms from influenza without the help of a PCR test....
While this might all suggest that the virus is evolving to become progressively less pathogenic, epidemiologists believe that the reality of the situation is more nuanced.
"The virus isn't necessarily less pathogenic," says Greg Towers, professor of molecular virology at University College London, UK. "Rather, it's infecting a population that are less inclined to become sick, because they've seen Sars-CoV-2 before, and they're better at regulating [their] immune response against it."...
Denis Nash, an epidemiologist at the City University of New York, US, says that people now experiencing Covid-19 for the very first time are at greater risk, especially if it has been a while since their last booster vaccine.
"There are still people who have somehow managed to remain completely Covid-näive," says Nash. "If they are unvaccinated or under vaccinated, they stand to have the highest risk of severe and protracted symptoms."...
This all indicates the ongoing importance for all age groups of remaining up to date with vaccine boosters, but while politicians have long been keen to move on from Covid, Strain says it is vital to keep monitoring how different variants continue to infect us.
"Symptoms do seem to change from one variant to another," he says. "We've had periods where the earliest symptom is headache, and others where it's more gastrointestinal. We all to go back to life as normal, but the reality is, Covid isn't going anywhere."