Well goal does have a crucial intentional component when used in the context of the mind. I still don't see what incompatibility that could have with materialism. I am unaware of any tradition that makes intention incompatible with materialism, and don't understand why it should be. Under materialism an intention is a state or process of the brain.
I would be interested in following up the Wittgenstein reference if you have it to hand, I would have thought that he would have considered any statement regarding Materialism as being meaningless.
Donald Davidson tries to make the case for intranslatability, he has (famously) shown that there is no problem
redescribing reasons as causes in the article "Actions, Reasons, Causes" from 1963. He then goes on to argue in "Mental Events" (1970) that there are no strict laws relating mental and physical events. And that therefore sentences about mental events cannot be losslessly translated into sentences of neuro-physiology. It is crucial to note that he nowhere denies that the mind is in essence a property of a physical system. What he argues is that the way the language we use to refer to mental events evolved has given rise to conceptual structures that cause problems for a strict reduction of true statements about mental events into physical ones. Generalisations are possible, just not strict laws. It is this latter sense in which I have problems with the suggested possibility for reduction, though not redescription.
With regards to Wittenstein I would hazard a guess to say that he would argue that the
grammar (see for instance Philosophical Investigations par. 371/373) of the term goal (the way we use the term on a day-to-day basis) carries with it a set of implicit assumptions (certainties he calls them in "On Certainty") that are incompatible with strict materialism. For instance the fact that people in general are
presumed to be free to act and could have chosen a different goal. Under a materialistic rediscription the notion "choice" would (maybe) be unrecognizable
as choice. In other words while we may redescribe "choice" as "the process by which our brains are caused to select a course of action" the fact that the latter phrase uses the passive mode belies the idea that choice is active, is causative not caused. [Note however that I don't think Wittgenstein ever explicitely argues this particular point, but it follows from his (later) works.]
Wittensteins view on the debate on materialism would (following the Tractatus) in all likelyhood not be that it is meaningless, but that it is non-sense.
All references are courtesy of the
Stanford Ecyclopedia of Philosophy. (My books are at home)