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Fake science is out of control

Apparently this Alzheimer's treatment was known to be without any merit long before the trials in which it apparently failed miserably. This is an article by Charles Piller who apparently has a book out about all kinds of other false promises when it comes to Alzheimers. Seems that fraud and hype are rife in this area.

The biopharma company Cassava Sciences announced today its experimental Alzheimer’s disease drug simufilam showed no signs of working in a phase 3 clinical trial. Volunteers who took the drug performed no better in cognitive or everyday-life activities than those who received a placebo. The announcement appears to mark the end of the company’s development of simufilam for Alzheimer’s, which has been marked by scandal and controversy.

“This is an expected result,” says Matthew Schrag, a Vanderbilt University neuroscientist who discovered many of the apparently doctored images cited in the complaint to FDA. “It remains alarming to me that the trial was permitted to continue to completion in view of the serious ethical concerns around the underlying science.” Schrag, who has conducted his assessments of Cassava’s work separately from his university duties, provided much of the basis for the citizen’s petition to FDA and has tracked the company since.

Elisabeth Bik, a leading forensic image sleuth, also identified many of the problems in Cassava’s studies—and was relentlessly attacked by boosters of the company on social media. The self-described “SAVAges,” a play on the company stock-ticker symbol, had for years lambasted Bik and other Cassava critics, including journalists who wrote about the company, in often-caustic and at-times threatening terms.

The company has only one drug in development, making its future uncertain at best. Its stock plummeted by more than 80% on the news—dropping about $1 billion in value.

“This is by no means the news we were hoping for,” Rick Barry, the company’s CEO, said in a conference call.

 
Apparently this Alzheimer's treatment was known to be without any merit long before the trials in which it apparently failed miserably. This is an article by Charles Piller who apparently has a book out about all kinds of other false promises when it comes to Alzheimers. Seems that fraud and hype are rife in this area.
This part:
Elisabeth Bik, a leading forensic image sleuth, also identified many of the problems in Cassava’s studies—and was relentlessly attacked by boosters of the company on social media. The self-described “SAVAges,” a play on the company stock-ticker symbol, had for years lambasted Bik and other Cassava critics, including journalists who wrote about the company, in often-caustic and at-times threatening terms.
So who are these "SAVAges"? Perhaps they'd like a little taste of their own medicine (pun intended ;))?

Bik is a hero.
 
This part:

So who are these "SAVAges"? Perhaps they'd like a little taste of their own medicine (pun intended ;))?

Bik is a hero.
This part:

So who are these "SAVAges"? Perhaps they'd like a little taste of their own medicine (pun intended ;))?

Bik is a hero.
Yeah, she is.

Apparently some of those boosters of Cassava have lost billions. Good!
 
Maybe this is something positive that RFK Jr's efforts can be actually employed to eradicate. If he concentrates solely on cleaning up this field properly, I'll give him props. Rather than dicking about killing US children by stupidly slowing or even withholding proven vaccines.
 
Maybe this is something positive that RFK Jr's efforts can be actually employed to eradicate. If he concentrates solely on cleaning up this field properly, I'll give him props. Rather than dicking about killing US children by stupidly slowing or even withholding proven vaccines.
He'll be more likely to make it easier for the fraudsters to thrive. He has a serious grá for fraudulent "medicine".
 
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