Of course, I support everyone's right to do whatever they please with their own bodies.
However, I can't really get myself to consider surgical or hormonal 'sex change' treatments sensible or advisable.
I can very well understand if someone does not want to follow the 'expected' dress code of his or her gender. Or if someone does not want to follow 'expected' gender behaviour. This is something I support politically and also instinctively. I'm not saying all gender 'roles' are absolute social evils, but it's good for everyone if this stuff becomes more optional.
However, when it comes to changing a perfectly functional body, this appears to me to fall in the same category as an anorectic woman removing some ribs to become unnaturally thin, or a man operating himself to get a gigantic penis because he somehow believes this is necessary for his self-esteem. The way I see it, it is not the body that is the problem.
I know there are studies suggesting that sex-change operations improve the well-being of patients. I'm a bit doubtful of these studies, because they all seem to have a very low response rate. If the people responding claim to have had their lives improved, that does not tell us that much, because there may be a very strong correlation between responding to the survey, and having had a positive change. Also, because it's a 'sunk cost' situation, self-evaluation after the fact is not a good measure. Rather, I would like to see a study where patients' well-being is first evaluated before treatment, and then re-evaluated with identical questions after the treatment, with serious efforts made to get a response from all patients.
The way I see it, we may be happy or unhappy with our bodies, but we are what we are. If we do not like our bodies, the solution must be to get ourselves to reconcile ourselves with them anyway, not to make attempts at surgically altering the bodies to somewhat better suit our wishes. If we want to engage in fantasies that we belong to the opposite sex, that is fine. If we want to involve others in that fantasy, that is also fine. I have no problem with that and I do not consider it wrong or pathological or anything. I respect that, absolutely. But I really doubt surgery or hormonal treatment is a solution.
Of course, this does not in any way excuse or mitigate the very widespread and serious persecution against transgender people. Such hatred seems to stem from people being themselves extremely unsure of their own sexuality, having a morbid fear of being 'fooled' by a person's gender appearance. Clearly, if one finds a person attractive, it could not reasonably matter one bit if that person has undergone a sex change operation, or has an appearance not typical of his or her genetic sex, or is dressing contrary to social norms. I consider myself heterosexual, but if one day I found myself romantically involved with someone who turned out to be equipped with a penis, or who was born with one, I'd simply draw the conclusion that I'm actually bisexual. The idea that the shape of someone's genitals should somehow be relevant in a situation where sexual attraction is already a fact, is beyond me.
However, I certainly understand that spouses of people undergoing a sex change operation are often not accepting. I do not believe I would be. Perhaps in the end I might tolerate it, perhaps not. I'm sure I would not be 'estranged' from a spouse for this reason, but I would expect it to probably lead to separation.