When I was fourteen, I tried on my sister's bra. That was the last time I ever did anything like that as I soon discovered that while being a fairly attractive male (when young), I made one ugly female.
In the scientific community, the way that a theory is disproved is to find ONE exception to the theory. Only one is necessary. Then it is up to the supporters of the theory to prove why their theory is still valid.
The prosecution's theory that the LCN DNA on the bra clasp meant that Raffaele participated in the murder is only a THEORY - and not a very good theory at that.
The theory that Guede's bloody palm print at the scene of the murder meant that he was there shortly after the murder, and therefore killed Meredith is very plausible. Guede was asked for an explaination of how his bloody print happened. He then gave the implausible explaination that we've all heard. A bloody print at the murder scene usually, and appropriately, results in a conviction.
However, the Bra String Theory is fraught with holes that need to be explained before anyone should believe it.