Stem Cells & Healing?

[PixyMisa]

There are multipotent and even pluripotent stem cells everywhere. It can even be found on skin and the blood stream although the number is exceedingly minute.

Thanks. I stand corrected on that point.

This still does not change the fact that Kumar is talking nonsense.

Yep.

 

[paximperium]

Thanks. I stand corrected on that point.

The number of pluripotent stem cells in blood is exceedingly small and a bit more limited. They are...not as pluripotent(yeah a bit of an oxymoron) which is why "adult stem cell" research is somewhat more difficult than using embryonic stem cells.

Placental cord blood is a great source for pluripotent stem cells.

 

[Kumar]

No. "Stem Cell" therapy as practiced by quacks is quackery and fraudulent nonsense.

Surprising? Even concentional medical educated people are involved in frauds. How regulating agencies can allow it?

 

[Kumar]

What about it?

Do you want to suggest that all other cells in body than blood cells are either don't need replacement or multiplied and replaced on their own?

 

[Kumar]

I stand corrected.

What's your point?

Thanks.

My point is that, other stem cells should also heve role in replacing old, worn out and damaged cells obiously where those dofferenciated normal cells can't compensate.

 

[Kumar]

There are multipotent and even pluripotent stem cells everywhere. It can even be found on skin and the blood stream although the number is exceedingly minute. This still does not change the fact that Kumar is talking nonsense.

In view of stem cells can be onmi-potent(!!), any number can serve the purpose. It is different issue that we mignt had resisted or restriced their interventions in healing & development due to our odd interventions & prefered modern lifestyle.

 

[Kumar]

Sure, the concepts do; but homoeopathy itself doesn't, which is why it doesn't work.

Being delicate(self body controlled not concentrated chemical & hard practices controlled) & individual, it may need faith, trust, dedication, placebo, reward expectation, dopamine etc. Even no real medicines, still it can have better cost benefit ratio in about 70% disorders(as told).

 

[Kumar]

This is true.

What you are missing is the difference between multipotent stem cells - such as those found in bone marrow - and pluripotent stem cells - such as those found in embryos.

Can't blame you for that; it's not obvious.

Where I am missing? I know in one post you intentionally mentioned pluripotent cells.. I mentioned stem cells--mean all type of stem cells are included.

Multipotent stem cells can turn into certain other types of cells. That's why they list the specific types of cells that bone marrow stem cells can produce.

Pluripotent stem cells can turn into any other type of cell. That's how we develop from an egg. Adult mammals don't have these.

Yes, there are many type of stem cells line(as explained in most links I provided).

In any case:


What may be beyond my scope? Your lack of understanding of biology and medicine? Perhaps, but we have plenty of biologists and doctors here on the forum if I ever get out of my depth.

Not true. You have to have something to teach. So far, your just plain wrong.[/quote]

Uptill now I could not be yet sure. Knowledge is not the property of academic educated people any one can learn or teach. In view of many unclarities as yet, research people do need brain storming points.

Three, specifically.


It's not "my preferred system", it's FACT.

We do at least know who is a fraud. The people who are promoting stem cell therapy for injuries? They're frauds. No such treatment exists.


Stem cell research is real, mainstream science.

Stem cell therapy is currently only used for some types of cancer.

Due to still many miss or weaknesses, atleast we can keep ourselves updated & dynamic to recognize & find gems among many coloured stones collected be our previous contributors.

 

[PixyMisa]

Surprising?

Sadly, not really.

Even concentional medical educated people are involved in frauds.

Yes.

How regulating agencies can allow it?

They don't, for the most part. But regulations are generally inadequate. For example, in the US there is a special loophole specifically for homepathy, so homeopathy is not subject to the same regulations as real medicine. If it were, there would be no practicing homeopaths in the US; they would all be in jail.

 

[PixyMisa]

Do you want to suggest that all other cells in body than blood cells are either don't need replacement or multiplied and replaced on their own?

Basically, yes, that is exactly what happens.

Some cells are never replaced at all; brain cells for the most part don't get replaced if they die.

 

[PixyMisa]

Thanks.

My point is that, other stem cells should also heve role in replacing old, worn out and damaged cells obiously where those dofferenciated normal cells can't compensate.

They don't. See above.

Being delicate(self body controlled not concentrated chemical & hard practices controlled) & individual, it may need faith, trust, dedication, placebo, reward expectation, dopamine etc.

No.

Homeopathy has been tested. It does not work.

It's also physically impossible, but most importantly, it does not work.

 

[Kumar]

The number of pluripotent stem cells in blood is exceedingly small and a bit more limited. They are...not as pluripotent(yeah a bit of an oxymoron) which is why "adult stem cell" research is somewhat more difficult than using embryonic stem cells.

Placental cord blood is a great source for pluripotent stem cells.

"multipotent-stem-cell-rich blood found in the umbilical cord has proven useful in treating the same types of health problems as those treated using bone marrow stem cells and PBSCs.

Umbilical cord blood stem cell transplants are less prone to rejection than either bone marrow or peripheral blood "
http://learn.genetics.utah.edu/content/tech/stemcells/sctoday/

I think multipotent cells are found in umbilical cord blood, pluripotent may not. People now are concentrating more on this source as embryonic stem cells becoming unethical & may even bring odd/uncalculated results.

 

[PixyMisa]

Where I am missing? I know in one post you intentionally mentioned pluripotent cells.. I mentioned stem cells--mean all type of stem cells are included.

The stem cells that could potentially allow us to regenerate are the pluripotent ones. Since adult mammals basically don't have any, we can't regenerate.

That's what you're missing. Well, one of the things.

Yes, there are many type of stem cells line(as explained in most links I provided).

None of which allow us to regenerate lost limbs. None of which are in circulation or take part in the normal healing process or in fighting disease.

Uptill now I could not be yet sure. Knowledge is not the property of academic educated people any one can learn or teach. In view of many unclarities as yet, research people do need brain storming points.

No they don't. At least, not such painfully wrong ones.

Due to still many miss or weaknesses, atleast we can keep ourselves updated & dynamic to recognize & find gems among many coloured stones collected be our previous contributors.

You are not presenting coloured stones. You are presenting bits of bark, leaves, dead insects and so on, and asking us each time if you've found a gem. We explain to you that you have not only not found a gem, you haven't even found a stone, and off you go again.

Here, Kumar, this is what your thinking leads to:

Stem Cell Tourist Dies From Treatment In Thailand

Last week, news that Costa Rica was shutting down a large stem cell clinic sparked a debate here on Slashdot about whether patients should be allowed to take the risks that come with untested treatments. Now comes news of what can happen when patients go looking for a shortcut. A patient suffering from an autoimmune disease that was destroying her kidneys went to a Bangkok clinic, where doctors injected her own adult stem cells into her kidneys. Now she's dead, and a postmortem revealed that the sites of injection had weird growths — 'tangled mixtures of blood vessels and bone marrow cells.' Researchers say the treatment almost certainly killed her.

The people researching stem cells are mostly good, honest scientists. The people pushing stem cell therapies are all too often outright frauds - and murderers. (Though it's likely this unfortunate woman would have died from her disease anyway, since autoimmune diseases can be very difficult to treat.)

 

[Kumar]

Sadly, not really.


Yes.

I liked on your unbiased reply.

They don't, for the most part. But regulations are generally inadequate. For example, in the US there is a special loophole specifically for homepathy, so homeopathy is not subject to the same regulations as real medicine. If it were, there would be no practicing homeopaths in the US; they would all be in jail.

It is not due to inadequacy or weaknesses of regulatory agencies. These agencies & even US govt. site on alternative medicines and other goverments all over the world suggest that they are well aware about homeopathy & even support & encourage it.

 

[Kumar]

Basically, yes, that is exactly what happens.

Some cells are never replaced at all; brain cells for the most part don't get replaced if they die.

I think it not there. Even neural cells are now getting regenarated(somewhat axon extension?). Simply, sten cells should be junping in when normal cells can't serve the purpose, otherwise normal cells involvements should be prefered in regenarating therapies instead of stem cells. This may suggest, stem cells system, if not compromised, scope should be beyong normal cells capacity/capability. Limited multiplication capacity & cell line is there for normal cells.

 

[Shadowdweller]

Pluripotent stem cells can turn into any other type of cell. That's how we develop from an egg. Adult mammals don't have these.

Minor, minor nitpitck, but you seem to be confusing pluripotence and totipotence here. Pluripotence just means that the cell has the capacity to become many other types - although from a research standpoint, the term frequently is used for cells (that are not normally found in adult mammals, as you say) that can differentiate into nearly any other cell type.

Totipotent cells, which are basically the first few that arise after conception, really CAN differentiate into any other cell of the organism in question. They're the ones that split away to form identical twins.

 

[Kumar]

They don't. See above.


No.

Homeopathy has been tested. It does not work.

It's also physically impossible, but most importantly, it does not work.

Limited multiplication & cell line capacity should be there for normal cells. Later, I shall give some referance justifying limited capacity of normal cells. Otherwise we would had not experianced wasting, atrophy or chronic wasting.

Whatever, homeopathy subject is just time wasting for us as both sides have their own but uncommon words .

 

[PixyMisa]

Minor, minor nitpitck, but you seem to be confusing pluripotence and totipotence here. Pluripotence just means that the cell has the capacity to become many other types - although from a research standpoint, the term frequently is used for cells (that are not normally found in adult mammals, as you say) that can differentiate into nearly any other cell type.

Totipotent cells, which are basically the first few that arise after conception, really CAN differentiate into any other cell of the organism in question. They're the ones that split away to form identical twins.

Oops. Yes, you're absolutely right, I was confusing pluripotent with totipotent.

 

[PixyMisa]

I liked on your unbiased reply.

Thanks.

It is not due to inadequacy or weaknesses of regulatory agencies.

Yes it is.

These agencies & even US govt. site on alternative medicines and other goverments all over the world suggest that they are well aware about homeopathy & even support & encourage it.

That's exactly what makes them inadequate.

Homeopathy doesn't work. That means that homeopaths are either deliberate frauds or at best are practicing medicine without a licence and promoting untested drugs. All of which are illegal - except for this stupid loophole that was slipped into the legislation decades ago.

Under a proper regulatory system, all homeopaths, naturopaths, chiropractors, reiki-whatevers, iridologists, and so on and so on would be in jail.

 

[PixyMisa]

I think it not there. Even neural cells are now getting regenarated(somewhat axon extension?).

There is some regeneration of neural cells, yes. But for the most part, they don't regenerate - for a long time it was thought they didn't regenerate at all.

Simply, sten cells should be junping in when normal cells can't serve the purpose

There is no "should be". They DON'T. End of story.

otherwise normal cells involvements should be prefered in regenarating therapies instead of stem cells.

Normal cells can't regenerate lost limbs either. That's why WE DON'T REGENERATE LOST LIMBS.

This may suggest, stem cells system, if not compromised, scope should be beyong normal cells capacity/capability.

The "scope" of stem cells is beyond that of normal cells. That's what makes them stem cells. For example, bone marrow produces blood cells.

But stem cells are not magic fairies. They do not regenerate lost limbs in mammals, and never have. They do not circulate. They do not take part in the normal process of healing or of fighting disease.

Limited multiplication capacity & cell line is there for normal cells.

Most of them, yes.