It would be very rare for two individuals to share exactly the same birth chart. Twins share similar charts, but they would be very slightly different - their ascendants would be a few degrees different (I degree every every 4 minutes), so would their Moon position and all the house cusps.
You've said this before, but my glance at astrodatabank.com---at least the comments section---I saw not one mention of features below the 15-degree level. Everyone was quoting the big features of the diagram: "square" seemed to mean "between 80 and 100 degrees", "opposition" seemed to mean "between 170 and 190 degrees" or so. No one was deriving anything from the fast-changing details; I'm a biased observer, but it looks to me like the "cusps" are ignored except when astrologers need a handy excuse for a failed prediction.
Since fate is not determined by karma, as explained above, thier vastly different lives would be explained by different environmental stimuli reacting with natal karma and changing it.
Take 100 people and put them in a burning warehouse. Take another 100 people and put them at a palm-lined beach resort. You might say, "I have no way of knowing who will escape the fire and be stronger for having faced death, nor who might drown in the ocean or choke on a fresh-picked fig. Environment doesn't predict everything." Then imagine that 30 years later you're given 200 biographies, and we ask you, "Can you tell which ones were in the burning-building cohort and which were in the oasis?" You wouldn't get them 100% right but you'd be able to do better than chance. Suppose that you can have either pro (+A) or anti (-A) astrological influence on something; you can also have pro (+E) or anti (-E) environmental. Some people will be +A+E, some will be -A-E. Your objection is simply to point out that there are also +A-E and -A+E. Well, unless the enviroment is correlated with the sign, then the set of +A people (a mix of +A+E and +A-E) will on average have "more pro" than the set of -A people (a mix of -A+E and -A-E). That's the point of the test---by using many subjects, the environment averages out while the astrology would add up.
Unless, of course, the "influences" are incredibly fragile---for example if "A" is zero. Look, a baby born under Mars square Neptune and the Great Red Spot under Ganymede! That means existential tendencies, strong loyalties, and crippling fear of insects. Oh ... wait, the infant was hit by a nitrogen molecule. That erases the loyalties, I'm afraid, so its 'loyalty' bit is random. Could be good, could be ... Ooh, darn it! They put a diaper on it, that's an environmental influence that could counter the existentialism. Or not. Hard to say! Ah, there they go, talking in baby talk which pretty much erases the lot. Sorry, parents, your baby's horoscope has been out-influenced by the environment and is no longer predictive, statistically or otherwise.
Happens every time.
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