More Fun with Homeopath Dana Ullman, MPH(!)

... snip ,,,

But heck, don't just listen to me...listen to your hero, Charles Darwin.

...snip ...

Good-bye for now...

Ok then,

You speak about Homœopathy; which is a subject which makes me more wrath, even than does Clair-voyance: clairvoyance so transcends belief, that one's ordinary faculties are put out of question, but in Homœopathy common sense & common observation come into play, & both these must go to the Dogs, if the infinetesimal doses have any effect whatever. How true is a remark I saw the other day by Quetelet, in respect to evidence of curative processes, viz that no one knows in disease what is the simple result of nothing being done, as a standard with which to compare Homœopathy & all other such things.It is a sad flaw, I cannot but think in my beloved Dr Gully, that he believes in everything— when his daughter was very ill, he had a clair-voyant girl to report on internal changes, a mesmerist to put her to sleep—an homœopathist, viz Dr. Chapman; & himself as Hydropathist! & the girl recovered.—
Letter to W.D. Fox, September 4th, 1850
 
Dana,

First comment on the Elia paper- even if true, what bearing do you think it has on the issue of homeopathy? It has no relevance whatsoever.

Second comment:

What is your opinion of the statistical methods used?

By the way, I would really hate to be wasting my time with this. I have paid real money, £28.43 to be precise, to download this paper and I would not be happy to be attempting to discuss its contents with a bullsh!tter who has not read the paper, but just tries to bluff his way using abstracts and second-hand quotations. So, simple question, what is the penultimate word on page 823?
 
I am reiterating part of my old posting to this list (and adding to it) because all of these issues below remained unanswered by skeptics

...

Sadly, I've grown tired of you, primarily due to your intellectual dishonesty.
Since you are so keen on "intellectual honesty", I'll assume that it's your comprehension skills that are the problem. I'll reiterate what I posted here (and add to it). I'll try to type slowly this time.


But heck, don't just listen to me...listen to your hero, Charles Darwin.
At least you aren't referring to him as anyone's God this time. That's progress, I guess.

Sometimes study with an N=1 provide important substantiation.

I take great pleasure to telling you a historical fact. Our greatly beloved Charles Darwin not only sought care from a highly respected homeopathic physician, it is unlikely that Darwin could have completed his seminal work, Origin of Species, in 1859, if he didn't receive this homeopathic care 10 year prior to its publication.
Do you have any evidence to support this assertion?

Just read Darwin's letters to read about this story and learn something about his life...
A good idea.

From 1837 onwards Darwin was frequently incapacitated with episodes of stomach pains, vomiting, severe boils, heart palpitations, trembling, and other symptoms. In 1847, Darwin's illness worsened. He was again experiencing frequent episodes of vomiting and weakness, but he now was also experiencing fainting spells and seeing spots in front of his eyes. Darwin wrote that he was so sick that he was “unable to do anything one day out of three.” He was so ill that he wasn’t even able to attend his father’s funeral when he died on November 13, 1848.

He went a month without vomiting, a very rare experience for him, and even gained some weight. One day he surprised himself by being able to walk seven miles. He wrote to a friend, “I am turning into a mere walking & eating machine” (Quammen, 2006, 112)
Here's the letter, dated 18th April 1849, from which that quotation was taken. Note the description of Gully's treatment: "the Water Cure".

And after just a month of treatment, Charles had to admit that Gully’s treatments were not quackery after all. After spending 16 weeks there, he felt like a new man, and by June he was able to go home to resume his important work (Grosvenor, 2004). Darwin actually writes that he is “of almost perfect health” (Burkhardt, 1996, 108).
And only 15 months later, in September 1850, he wrote:
You speak about Homœopathy; which is a subject which makes me more wrath, even than does Clair-voyance: clairvoyance so transcends belief, that one's ordinary faculties are put out of question, but in Homœopathy common sense & common observation come into play, & both these must go to the Dogs, if the infinetesimal doses have any effect whatever. How true is a remark I saw the other day by Quetelet, in respect to evidence of curative processes, viz that no one knows in disease what is the simple result of nothing being done, as a standard with which to compare Homœopathy & all other such things. It is a sad flaw, I cannot but think in my beloved Dr Gully, that he believes in everything— when his daughter was very ill, he had a clair-voyant girl to report on internal changes, a mesmerist to put her to sleep—an homœopathist, viz Dr. Chapman; & himself as Hydropathist! & the girl recovered.—
He doesn't seem to have been very convinced of the merits of homoeopathy, does he?

Although some medical historians have referred to Gully as a hydrotherapist, this is just the historians way of writing homeopathy out of history. Gully considered himself to be a homeopath, and while his staff provided various treatments to Darwin, Gully's treatment was primarily homeopathic medicines.
Note that in the letters above, Darwin refers to Gully's regime as "the Water Cure". Note that he describes Gully as acting as a "Hydropathist", who needed a second "doctor", one "Dr. Chapman", to provide homoeopathic treatment for his daughter. Note the description of Gully's regime in this letter, from which you quoted the last time you told your Darwin story:
As you say you want my hydropathical diary, I will give it youf1 —though tomorrow it is to change to a certain extent.— 1⁄4 before 7. get up, & am scrubbed with rough towel in cold water for 2 or 3 minutes, which after the few first days, made & makes me very like a lobster— I have a washerman, a very nice person, & he scrubs behind, whilst I scrub in front.— drink a tumbler of water & get my clothes on as quick as possible & walk for 20 minutes—f2 I cd. walk further, but I find it tires me afterwards— I like all this very much.— At same time I put on a compress, which is a broad wet folded linen covered by mackintosh & which is “refreshed”—ie dipt in cold water every 2 hours & I wear it all day, except for about 2 hours after midday dinner; I don't perceive much effect from this of any kind.— After my walk, shave & wash & get my breakfast, which was to have been exclusively toast with meat or egg, but he has allowed me a little milk to sop the stale toast in. At no time must I take any sugar, butter, spices tea bacon or anything good.—f3 At 12 oclock I put my feet for 10 minutes in cold water with a little mustard & they are violently rubbed by my man; the coldness makes my feet ache much, but upon the whole my feet are certainly less cold than formerly.— Walk for 20 minutes & dine at one.— He has relaxed a little about my dinner & says I may try plain pudding, if I am sure it lessens sickness.—

After dinner lie down & try to go to sleep for one hour.— At 5 olock feet in cold water—drink cold water & walk as before— Supper same as breakfast at 6 oclock.— I have had much sickness this week, but certainly I have felt much stronger & the sickness has depressed me much less.— Tomorrow I am to be packed at 6 oclock A.M for 1 & 1⁄2 hour in Blanket, with hot bottle to my feet & then rubbed with cold dripping sheet;f4 but I do not know anything about this.— I grieve to say that Dr Gully gives me homoœopathic medicines three times a day, which I take obediently without an atom of faith.
The homoeopathy seems to have been only a small component of these shenanigans.

In your earlier post on this subject, you posted,
After being at Dr. Gully’s spa for just nine days, Darwin laments that Gully had prescribed homeopathic medicine to him, “I grieve to say that Dr. Gully gives me homeopathic medicines three times a day, which I take obediently without an atom of faith.”

And even though Darwin was extremely skeptical, just two days later (March 30, 1849) Darwin acknowledged, “I have already received so much benefit that I really hope my health will be much renovated”
Thus giving the impression that he ascribed his "cure" to the homoeopathic treatment. Here's the letter from which your quotation comes; the whole sentence, of which you quoted only part, reads:
I am now not at home (though I have so dated this letter) but have come to Malvern for two months to try the cold water cure, and I have already received so much benefit that I really hope my health will be much renovated.
Does he attribute his improvement to homoeopathy?

Even Gully does not seem to have been entirely convinced about the merits of homoeopathy. From here:
Gully was strongly against the administration of medical drugs for chronic disorders (Gully 1846, p. 513 n.) and cautious in his use of homoeopathic remedies: ‘although I might be induced to try to subdue a passing but troublesome symptom, I could not trust to remove the essential nature of a chronic malady by homœopathic means’ (Gully 1846, p. 83 n.).
He "might be induced to try" homoeopathy to "subdue a passing but troublesome symptom"? Hardly a resounding endorsement of a "holistic" therapy.

And, just in case you missed it the second time I posted it, I'll repeat what Darwin wrote about a year and a half after you claim he conceded that homoeopathy had cured him:
You speak about Homœopathy; which is a subject which makes me more wrath, even than does Clair-voyance: clairvoyance so transcends belief, that one's ordinary faculties are put out of question, but in Homœopathy common sense & common observation come into play, & both these must go to the Dogs, if the infinetesimal doses have any effect whatever. How true is a remark I saw the other day by Quetelet, in respect to evidence of curative processes, viz that no one knows in disease what is the simple result of nothing being done, as a standard with which to compare Homœopathy & all other such things. It is a sad flaw, I cannot but think in my beloved Dr Gully, that he believes in everything— when his daughter was very ill, he had a clair-voyant girl to report on internal changes, a mesmerist to put her to sleep—an homœopathist, viz Dr. Chapman; & himself as Hydropathist! & the girl recovered.—
 
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I took a look at the Elia paper. It does relate to an homeopathy concept indeed ('structure of water'). I have a slight problem however :

The actual experimental procedure, ie, materials & methods, type of water used ('bidistilled' looks cool, but does not tell me much), containers, ect. is incomplete.

The thing is that ultrapure water (water that has been purified up to having a resistance around 18 MOhms) will dissolve pretty much anything. Even some of the boron contained in ordinary glass (I personnaly have measured this). If walls of container were attacked somehow, it could explain slight deviation in calorimetric testing, without resorting to 'structure of water'.
 
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First of all it’s in Pediatr Infect Dis J. not PEDIATRICS :D
Pediatric Inf Dis J. : Impact factor 1.819
Pediatrics : Impact factor 2.710

BTW the article can be found here you might want to show it so we can all see what we are discussing.


But you are right, indeed most of the research in it is based on data from Nicaragua, from previously published data. It has been looked at quite extensively…

A report in May 1994 examined the homeopathic treatment of diarrhea in children who lived in Nicaragua [7]. On Day 3 of treatment the homeopathic group had one less unformed stool than the control group (3.1 Vs 2.1; p <.05). However, critics [8] pointed out that not only were the sickest children excluded, but there were no significant differences on Days 1, 2, 4, or 5. This suggests that the conclusion was not valid. Further, there was no assurance that the homeopathic remedy was not adulterated (contaminated). Finally, standard remedies which halt diarrhea were not used for comparison purposes.

And : The Nepal trial was not significant p=0.06 as you may have read in the paper you suggested

WELL...LOOK AT THE ENTIRE SET OF STUDIES...OR DO YOU PREFER TO SQUINT YOUR EYES SO MUCH THAT YOU CANNOT SEE THEM?

Just a few questions right of the bat… :)

1) Why do you think it is relevant or a good study?
BECAUSE THE TREATMENT GROUP DID SIGNIFICANTLY BETTER THAN THE PLACEBO GROUP, VERIFYING THAT THE PLACEBO "EXPLANATION" TO HOMEOPATHIC TREATMENT IS INADEQUATE.

2) What conclusion would you attribute to the fact that on day 3 there were less then 2 unformed stools but on the days before day 3 and after day 3 there was no significant difference?

ACTUALLY...FROM THE 1ST DAY TO THE 5TH DAY, THE TREATMENT GROUP EXPERIENCED LESS DIARRHEA (p=0.013).

3) What do you think has a better effect ORS or a homeopathic drug (yet undefined, since it changed according to the prescriber)


YOU MEAN ORT...SOMETIMES, IT IS NOT EITHER/OR. IN THIS CASE, THE GROUP WHO GOT HOMEOPATHY AND ORT DID BETTER THAN THOSE WHO JUST GOT ORT.

SYL :)

Here's the letter, dated 18th April 1849, from which that quotation was taken. Note the description of Gully's treatment: "the Water Cure".

DARWIN COULD NOT SEEM TO BE A SUPPORTER OF HOMEOPATHY IF HE WANTED ANY SUPPORT FROM ORTHODOX SCIENTISTS AT THAT TIME. AND YET, THE RESULTS SPEAK FOR THEMSELVES. AFTER 12 YEARS OF VERY SERIOUS PROBLEMS WITH HIS HEALTH AND AN INABILITY TO WORK ONE OUT OF THREE DAYS, HE EXPERIENCED REAL RELIEF FOR THE FIRST TIME. HMMMMM.

IT IS INTERESTING TO NOTE THAT NO ONE HERE HAS COME FORWARD TO DECLARE THAT HYDROTHERAPY IS AN IMPORTANT TREATMENT. COME ON NOW...EVERYONE INTO COLD WATER TREATMENT NOW!

IN THE MEANTIME, I WON'T DISCLOSE THE "HOMEOPATHIC STUDIES" THAT DARWIN CONDUCTED UNTIL MY FORTHCOMING BOOK IS PUBLISHED.

Note that in the letters above, Darwin refers to Gully's regime as "the Water Cure". Note that he describes Gully as acting as a "Hydropathist", who needed a second "doctor", one "Dr. Chapman", to provide homoeopathic treatment for his daughter. Note the description of Gully's regime in this letter, from which you quoted the last time you told your Darwin story:
The homoeopathy seems to have been only a small component of these shenanigans.

YOU HAVE TO LOVE THE FACT THAT YOU CALL SOMETHING THAT PROVIDED IMPRESSIVE BENEFITS TO CHARLES DARWIN AS "THESE SHENANIGANS."

ONCE AGAIN, DARWIN COULD NOT ADMIT OPENLY THAT HE SOUGHT OUT HOMEOPATHIC TREATMENT. COULD HE? LOOK AT WHAT YOUR REACTIONS HAVE BEEN.

Even Gully does not seem to have been entirely convinced about the merits of homoeopathy. From here:
He "might be induced to try" homoeopathy to "subdue a passing but troublesome symptom"? Hardly a resounding endorsement of a "holistic" therapy.

BY THE WAY...I HAVE A COPY OF GULLY'S 1846 BOOK, AND THERE IS NO REFERENCE TO THAT STATEMENT ON PAGE 83...AND THE BOOK ENDS ON PAGE 405, SO ANOTHER PERSON'S STATEMENT ABOUT PAGE 500+ IS DUBIOUS TOO.

MEDICAL HISTORIANS CONFIRM THAT GULLY WAS A HOMEOPATHY AND A HYDROTHERAPIST...BUT HECK, PEOPLE HERE HAVE BLINDERS ON AND HAVE NO SENSE OF HISTORY.
 
An awful lot of shouting from someone who has yet to answer some simple questions, including mine.

I won't copy them all (again)... I'll just ask one simple one:

What is the success rate for syphilis with Hahnemann's homeopathic methods versus antibiotics? (knowing that one of the miasms that Hahnemann thought that existed was "syphilis").
 
Understanding Samuel Hahnemann, MD

Hey HC...
I apologize for the shouting. I haven't figured out how to do the quoting with a posting. I instead chose to differentiate my words from others by using capital letters.
Hahnemann was respected enough that he was voted as an honorary member of the NY medical society in 1832, though he was voted out in 1843 just one week after his death because the medical society said that homeopathy was too much of an ideological and "economic" threat.
Although many people who were uninformed about homeopathy make fun of Hahnemann's concept of miasms, this concept were some of the earliest sophisticated insights about genetic disease. Hahnemann determined that people with syphilis, gonorrhea, and TB didn't die immediately, but during their disease process they gave birth (or sperm), and this new human being's health was influenced by the diseases of the mother and father. Such child would not have syphilis, gonorrhea, or TB, but they would have specific symptoms that were associated with each of their "miasms."
As for other biographical info about the man, here's an excerpt from my forthcoming book:

In America’s capital city, Washington, DC, the only monument honoring a physician is one to the founder of homeopathic medicine, Samuel Hahnemann, MD (1755-1843). This monument was dedicated in 1900 by President William McKinley.
Although trained as a medical doctor, Hahnemann was a learned chemist and author of the leading German textbook for apothecaries (pharmacists) of the day. He was conversant in at least nine languages and even supported himself in his mid-20s teaching languages at the famed University of Leipic.
Learning these languages enabled him to become familiar with the latest developments in medicine and science throughout the western world. He further expanded his knowledge and his growing prestige by translating 22 major textbooks, primarily medical and chemistry textbooks (several of which were multi-volume works). Over a 29 year period, Hahnemann translated a total of 9,460 pages.
Prior to his discovery of homeopathy, Hahnemann’s respect as a physician brought German royalty to seek his medical care, and modern medical historians confirm that Hahnemann “showed sound balance and good judgment” in his advocacy of proper diet, fresh air, and exercise as a method of treatment. His promotion of hygienic measures during epidemics won him praise as a public health advocate, and his kind rather than cruel and harsh treatment of the insane granted him a place in the history of psychiatry (Rothstein, 1972, 152).
It is not surprising to know that Hahnemann was a Freemason, the esoteric fraternal organization and secret society of men who shared certain moral and metaphysical ideals.
Hahnemann stopped practicing conventional medicine of that day because he felt that he was doing more harm than good. Instead, he made a living for his family of 11 children as a translator. During the translation of a book by William Cullen, the leading physiologist of that time, Hahnemann noted that Cullen asserted that the reason that Peruvian bark was an effective drug for malaria was due to its bitter and astringent properties. Hahnemann thought this was a peculiar statement because he knew more bitter and astringent medicines, but they provided no benefit in the treatment of malaria. He then conducted an experiment upon himself where he took this herb twice a day until he developed symptoms of its toxicology, and here he discovered that it created a fever with chills as well as other symptoms that were similar to malaria. Hahnemann proposed that Peruvian bark (which contains quinine) may be effective for treating people with malaria because it has the capacity to cause similar symptoms.
Hahnemann ultimately conducted upon himself experiments with 90 other substances, and his colleagues and friends also engaged in these experiments. He had found a consistent pattern from these experiments, that is, he found that various substances in overdose create their own unique syndrome of symptoms and that whatever syndrome a substance causes in toxic dose, it can and will elicit a healing response when given in specially prepared small doses to people who have similar symptoms of pathology.
Hahnemann observed that sick people were hypersensitive to the medicine to which might cause similar symptoms as they were experiencing, and because of this, Hahnemann began using smaller and smaller doses. Being a chemist, he experimented with various ways to make these doses of medicines both safe and effective. At different times over the next 40 years, he diluted the medicines 1:10, 1:100, or 1:50,000, with vigorous shaking in-between each dilution, and he consistently found that exceedingly small doses of medicines had powerful therapeutic effects when prescribed according to his principle of similars.
Being the incredibly avid experimenter, Hahnemann did not come easily or quickly to his conclusions about the exceptionally small doses he and his colleagues found effective. In fact, he first wrote about homeopathy in 1796, and for the next 30 years (!) he primarily used doses that are today considered “low potencies.” Further, in 1829, a homeopathic physician wrote him about his successes in using potencies that were dilution 1:10 over 200 times, and Hahnemann expressed several skepticism for such actions until he himself found that these “higher potencies” were surprisingly effective Bradford, 1895, pp 455-6).
Although people who are unfamiliar with homeopathy have questioned the logic and the efficacy of the doses that homeopaths use, these people are inevitably inadequately informed of the history of development of homeopathy and are similarly ignorant of the body of scientific and empirical evidence of homeopathy’s successes.
Ultimately, Hahnemann authored three major books on homeopathy, including six editions of his seminal work on homeopathy, The Organon of the Healing Art, continually updating and refining this science and art.
Christoph Wilhelm Hufeland, MD (1762-1836), Germany’s most well known and respected physician of his day, was as famous as Goethe and Schiller in the early 19th century. As the editor of the leading medical journal in Germany called Journal of Practical Medicine, Hufeland published some of Hahnemann’s writings, and he held an extremely high regard for him. “I have discovered in him an amplitude of knowledge, clearness of mind, and a spirit of tolerance, which last is the more worthy of notice in him.” Hahnemann is “one of our most distinguished, intelligent and original physicians” (Everest, 186).
Even though Robert Koch first discovered the cholera bacteria in 1883, as early as 1831 Hahnemann ascribed the cause of the cholera epidemics that raged during that time to a “an enormously increased brood of those excessively minute, invisible, living creatures so inimical to human life, of which the contagious matter of the cholera most probably consists” (Hahnemann, 1831).
Nicholas Von Hoffman, a columnist for the Washington Post, wrote, “Samuel Hahnemann lived from 1755 to 1843 and, although this German physician never visited the U.S., for 70 years or more his ideas tore up and divided American medicine. No other single individual causes the settled and comfortable structures of this profession the trouble Hahnemann did, and even now many of the questions he raised have not been answered.”
Even many of homeopathy’s most severe critics have had kind words for Samuel Hahnemann. Morris Fishbein, the Executive Director of the American Medical Association, wrote that “the influence of Hahnemann was, on the whole certainly for the good. He emphasized the individualization of the patient in the handling of disease…and he demonstrated the value of testing the actual virtues of a drug by trial” (Fishbein, 1925, 37).
Despite Hahnemann’s significant contributions to medicine, pharmacy, chemistry, psychiatry, and public health, he remained a humble man. “I do not ask during my lifetime any recognition of the beneficent truth, which I, without any thought of myself, offer. What I have done, I did from higher motives for the world. Non inutilis vixi (I have not lived in vain).”
On the Hahnemann Monument in Washington, DC, are those Latin words. Indeed, Dr. Samuel Hahnemann did not live in vain.
 
Syl:
First of all it’s in Pediatr Infect Dis J. not PEDIATRICS
Pediatric Inf Dis J. : Impact factor 1.819
Pediatrics : Impact factor 2.710

BTW the article can be found here you might want to show it so we can all see what we are discussing.


But you are right, indeed most of the research in it is based on data from Nicaragua , from previously published data. It has been looked at quite extensively…

A report in May 1994 examined the homeopathic treatment of diarrhea in children who lived in Nicaragua [7]. On Day 3 of treatment the homeopathic group had one less unformed stool than the control group (3.1 Vs 2.1; p <.05). However, critics [8] pointed out that not only were the sickest children excluded, but there were no significant differences on Days 1, 2, 4, or 5. This suggests that the conclusion was not valid. Further, there was no assurance that the homeopathic remedy was not adulterated (contaminated). Finally, standard remedies which halt diarrhea were not used for comparison purposes.

And : The Nepal trial was not significant p=0.06 as you may have read in the paper you suggested

James:
WELL...LOOK AT THE ENTIRE SET OF STUDIES...OR DO YOU PREFER TO SQUINT YOUR EYES SO MUCH THAT YOU CANNOT SEE THEM?

Syl:
Just a few questions right of the bat…

1) Why do you think it is relevant or a good study?

James:
BECAUSE THE TREATMENT GROUP DID SIGNIFICANTLY BETTER THAN THE PLACEBO GROUP, VERIFYING THAT THE PLACEBO "EXPLANATION" TO HOMEOPATHIC TREATMENT IS INADEQUATE.

Syl:
2) What conclusion would you attribute to the fact that on day 3 there were less then 2 unformed stools but on the days before day 3 and after day 3 there was no significant difference?

James:
ACTUALLY...FROM THE 1ST DAY TO THE 5TH DAY, THE TREATMENT GROUP EXPERIENCED LESS DIARRHEA (p=0.013).

Syl:
3) What do you think has a better effect ORS or a homeopathic drug (yet undefined, since it changed according to the prescriber)

James:
YOU MEAN ORT...SOMETIMES, IT IS NOT EITHER/OR. IN THIS CASE, THE GROUP WHO GOT HOMEOPATHY AND ORT DID BETTER THAN THOSE WHO JUST GOT ORT.

SYL :)
:) Indeed a screemer, but I'll take your word for it that you were trying to differentiate the text. There are other ways to do that then using CAPS lock. (CAPS lock is basically considered rude/ bad behaviour)


I suggest you play with the method of quoting, copying and pasting for a while. You just have to click the add quotation square before you reply. Then you move the /quote to the point you want to quote something. Move the start of the quotation to the start of the next part you want to quote.
If this sounds to complicated… Just select the add quotation square and edit out the parts you are not responding or which you want to skip for brevity. You can do this several times by copying and pasting the same original quote.

I have especially tried to be nice by asking the simple questions that would invite you into the discussion. There are a lot more general damning questions that can be asked about homeopathy…
So I propose you remain civil and try to look at them from an open point of view as we have.

----------------

Now for my questions… :D
Let me explain what is said here so you understand the criticism:

“A report in May 1994 examined the homeopathic treatment of diarrhea in children who lived in Nicaragua [7]. On Day 3 of treatment the homeopathic group had one less unformed stool than the control group (3.1 Vs 2.1; p <.05).”

I'll get back to this further down...

“ However, critics [8] pointed out that not only were the sickest children excluded, but there were no significant differences on Days 1, 2, 4, or 5.”

This points to something called selection bias. The significance of time is something I will get back to in a minute.

“ This suggests that the conclusion was not valid. Further, there was no assurance that the homeopathic remedy was not adulterated (contaminated).”

We don’t have a guarantee of what was actually given, so the actual effect and composition of the medication is at best dependent on hearsay. Remember that IR spectroscopy can identify crystals and salts, but needs preparation of the sample and the end result merely states that there was no difference between them, not what was in it.

“ Finally, standard remedies which halt diarrhea were not used for comparison purposes.”

So what was the benefit? If both ORT (=ORS in my part of the world) was given in together with homeopathic solutions, how do you know the effect was to be attributed to the homeopathic solution? How do you know it did better or worse than ORT?
The effects were compared in a meta-analysis of different population groups in different parts of the world with different causes of diarrhea, different water supply, general health etc…
They say they have no reason to think there was a difference between the groups, but show no data, furthermore cultural and socio-economic differences are to be expected between Nepal and Nicaragua. No data, just a statement without any foundation for it. Basically microbiological agents in different parts of the world are different with different virulence. No data again, not even a statement this time. Some of these are endemic, some are not, but I'll leave that out of this discussion. You have enough to worry about.

If we would compare the effect of homeopathic treatment here and in a third world country, I recon that in third world countries the effects might be better. At least they are getting clean water and enough attention… ;)

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In response to :” WELL...LOOK AT THE ENTIRE SET OF STUDIES...OR DO YOU PREFER TO SQUINT YOUR EYES SO MUCH THAT YOU CANNOT SEE THEM?”

I am looking at the total picture… and at the details of the study like anyone with a critical mind would do. Since the criticism above is on half of the data, this is relevant to address.

-----------------

In response to: “2) What conclusion would you attribute to the fact that on day 3 there were less then 2 unformed stools but on the days before day 3 and after day 3 there was no significant difference?

ACTUALLY...FROM THE 1ST DAY TO THE 5TH DAY, THE TREATMENT GROUP EXPERIENCED LESS DIARRHEA (p=0.013).”

The p=0.013 tells you there is a difference between the two curves, but it does not tell you the end-result. It merely tells you that the curves are significantly different. When you look at the curves, they diverge on day 3, but come together on day 4 at day 5 they are almost the same as on day 2. This is why many of the better Infectious Disease Jornals require that you also give the percentiles table, which shows you the survival distribution for the first, median and third quartile of the survival distribution.

Kaplan Meier curves are often used to evaluate survival, this has a purpose because you can tell at a certain point in time that more or less people have survived after treatment. In this case the divergence of the curve occurs in the middle of the disease process during treatment. The end result however, does not seem to be affected.

By placing the cut-off point the way the authors did, a significant difference in the curves resulted is a difference achieved on day 3.1 vs 3.8, but looking at the curves of patients with diarrhea, you see they converge after day 3. This is questionable. Furthermore the reporting was done by the parents. This is not a very reliable way of doing so, and by measuring the number of stools, not volume or diaper weight. Furthermore, daily visit concerning the health of the child may lead to observer bias by the parent. So double blind

110 controls x 51.4%= 57 diarrhea , 53 cured
120 cases x 38.1%= 46 diarrhea, 74 cured

If you want to get this exact table the probability of the getting this exact table is p=0.013, but the significance of the Chi Square value for the Odds ratio’s (which is is Pearson uncorrected if you want it to be significant is 4.22 with p=0.047 in SPSS) is questionably significant (Yates corrected Chi-Square= 3.693 with a p= 0.055 this is normally done when one of the cells reaches 10 and df =1 because Pearson uncorrected Chi-Square becomes too unreliable, not strictly necessary but reveals a more certain evaluation of significance) and resembles the major contribution to the meta-analysis, the Nepal trial. This last trial was not significant. These numbers tell you something about the differences between the groups ( not the chance of getting the exact distribution, which has little to do with the effect of a drug). If you think I'm wrong, let me know... :)

Basically there is no or a barely significant improvement on day 5 when you look at it objectively and their results all pivots on what you call diarrhea, who you exclude, when you exclude them, who does your evaluation and how they do it, not to mention dredging for statistically significant results at all cost.

Furthermore the repeated study by the same author( presented by fls in her post) corrects her statements and says there is no significant difference. That should tell you enough... :)
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In response to:
3) What do you think has a better effect ORS or a homeopathic drug (yet undefined, since it changed according to the prescriber)

YOU MEAN ORT...SOMETIMES, IT IS NOT EITHER/OR. IN THIS CASE, THE GROUP WHO GOT HOMEOPATHY AND ORT DID BETTER THAN THOSE WHO JUST GOT ORT.

Now they both got a drug ORT and were treated for parasites and bacteria and all other diseases, yet the difference that was seen was attributed to the homeopathic solution….

These other things could be called confounding factors and they disrupt the analysis of the effect of the homeopathic solution, which does not seem to be very strong in the first place.

It also raises the question, what differences in the cause of the diarrhea were observed. A general remark is made but the numbers are absent. The cause of the diarrhea and the type of diarrhea seem important in the design of the study… Don’t you agree?

---------------
Now you said something interesting while answering the question why you thought this study was relevant or a good study: "BECAUSE THE TREATMENT GROUP DID SIGNIFICANTLY BETTER THAN THE PLACEBO GROUP, VERIFYING THAT THE PLACEBO "EXPLANATION" TO HOMEOPATHIC TREATMENT IS INADEQUATE."
You are saying that it is relevant or good merely because 1) homeopathy did better then the placebo 2)because the placebo explanation seemed inadequate.
This says nothing about the quality of the study or it's relevance to medical practice. It does however say something about the way you look at a study. The study was poorly designed, not well executed and poorly analyzed with the intent to show a significant result, overstating the significance and meaning of the results. Your answer to my question was not about the quality of the study or the relevance to medical practice or science as a whole, but about the importance of the study to the endorsement of homeopathy.
So let's not lecture about science, but rather try to contribute to it. We are all fallible, even scientists... :D

I don’t want to swamp you. So I’ll leave the other questions for the other members.

SYL :)
 
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BTW James

Many are aware of the medical history surrounding both conventional medicine and homeopathy. I don't think many of us would contradict that Hahnemann did some good in his time, when medicine was built on different foundations as modern medicine and used things such as blood letting and mercurochrome solutions. It is very well possible that his brand of medicine compared to the medical practice of his time was less bad for the patient and led to better results. Many things have changed, modern medicine has evolved using science to better itself. Homeopathy hasn't. There is the rub.

You might want to leave the past and look into the present and future...
It's more productive...

SYL :)
 
DARWIN COULD NOT SEEM TO BE A SUPPORTER OF HOMEOPATHY IF HE WANTED ANY SUPPORT FROM ORTHODOX SCIENTISTS AT THAT TIME.
you chose Darwin's letters as the text to consider, and claimed that they showed that he supported homoeopathy.
JamesGully said:
Just read Darwin's letters to read about this story and learn something about his life...
Can you produce any evidence that this is the case?

IN THE MEANTIME, I WON'T DISCLOSE THE "HOMEOPATHIC STUDIES" THAT DARWIN CONDUCTED UNTIL MY FORTHCOMING BOOK IS PUBLISHED.
Drosera?
 
DARWIN COULD NOT SEEM TO BE A SUPPORTER OF HOMEOPATHY IF HE WANTED ANY SUPPORT FROM ORTHODOX SCIENTISTS AT THAT TIME.


Of course, Darwin is famous for never publishing anything that he feared might upset prevailing viewpoints. ;)

On the origin of Species... also shows us Darwin's approach to ideas he thought plausible but feared might be controversial: while reluctant to publish, he discussed the idea of evolution by natural selection in his private correspondence. If, as you claim, he supported homoeopathy but was reluctant to do so publicly, his letters would be the very place we would expect to see statements of his views on the matter.

What we actually find there is:
You speak about Homœopathy; which is a subject which makes me more wrath, even than does Clair-voyance: clairvoyance so transcends belief, that one's ordinary faculties are put out of question, but in Homœopathy common sense & common observation come into play, & both these must go to the Dogs, if the infinetesimal doses have any effect whatever. How true is a remark I saw the other day by Quetelet, in respect to evidence of curative processes, viz that no one knows in disease what is the simple result of nothing being done, as a standard with which to compare Homœopathy & all other such things. It is a sad flaw, I cannot but think in my beloved Dr Gully, that he believes in everything—

If he wished not to be seen as a supporter of homoeopathy, all he had to do was not support it. However, what we find is a clear opposing statement.
 
IN THE MEANTIME, I WON'T DISCLOSE THE "HOMEOPATHIC STUDIES" THAT DARWIN CONDUCTED UNTIL MY FORTHCOMING BOOK IS PUBLISHED.
Not a publication in Nature then?
 
DARWIN COULD NOT SEEM TO BE A SUPPORTER OF HOMEOPATHY IF HE WANTED ANY SUPPORT FROM ORTHODOX SCIENTISTS AT THAT TIME. [...] ONCE AGAIN, DARWIN COULD NOT ADMIT OPENLY THAT HE SOUGHT OUT HOMEOPATHIC TREATMENT. COULD HE? LOOK AT WHAT YOUR REACTIONS HAVE BEEN.

So Charles Darwin, who was not afraid to shock the world by asserting that humans and apes descended from a common ancestor, would have been afraid to admit that he did something as daring as using a homeopathic treatment?
 
IT IS INTERESTING TO NOTE THAT NO ONE HERE HAS COME FORWARD TO DECLARE THAT HYDROTHERAPY IS AN IMPORTANT TREATMENT. COME ON NOW...EVERYONE INTO COLD WATER TREATMENT NOW!

Well after reading his "hydropathical diary", I find that part of the hydrotherapy treatment included an increase in exercise and an improved diet. Both (now) well known to be helpful in the promotion of good health...
 
It is not rigmarole - it is consultation leading to an individualized remedy or series of remedies to be decided as the case progresses that we are talking here - and the series would nearly always be different for each person.

Well, yes. Homeopathic procedure.

So we are not testing a remedy - we are rather testing homeopathy against placebo( and I have noted that some here call the remedy placebo!).

Yes, we are testing the remedy, because the only difference between the placebo group and the verum group is that the latter receives remedies.

Both groups are subjected to the "homeopathic procedure". So, if there is a difference, it must be due to a property of the remedies. If there is no difference, the conclusion is that the remedies have no properties different from placebo.

And yes, one of the claims of the skeptics is that homeopathic remedies equal placebo.

Such are the difficulties in deciding "proper testing conditions "

I still fail to see the difficulties. Admitted, a properly conducted trial, with individualized treatment, will be fairly complex. More complex than a single drug trial, but there are certainly no insurmountable problems.

If there is consensus that randomly allotting patients to receive placebo and homeopathy (series of remedies as required) (placebo?) is acceptable proof - then if there is any significant difference (favourable to the latter) - would it be acceptable proof that homeopathy is not placebo?

A properly designed and executed double blinded, randomized, placebo controlled trial of homeopathy with a positive result would be considered important evidence that there is reason for further research.

The reason for this rather reserved position is that IF homeopathy works, a considerable part of present science will have to be revised, thus overthrowing the very solid body of evidence that exist for it. Therefore, such a revision will require extremely strong evidence (remember, even a statistical 99% confidence still leaves a 1% possibility of a spurious result)

Therefore, I don't think a single trial result, even if well conducted, will immidiately convert the scientific world in favor of homeopathy. It will, however, no doubt motivate further serious research. And it will certainly open the door to widespread publication.

Hans
 
On the discussion regarding India and its homeopathic goodness:

India is the scam artist's dream land. Every sort of quackery imaginable is practiced there. It is a land of incredible superstitions and mass quantities of poor, uneducated people. Given the incredible corruption of the wonderful socialist government of India, competent medical care is available only for the select few. Often times, whether a person will receive good medical care depends upon his caste; low caste people lose. In fact, those Indians who can afford the expense will travel to Europe or (their favorite place to go) the U.S. for serious problems. Furthermore, aspiring Indian medical students do all they can to get out of India and study abroad. Why is this? Visit India sometime and it will become apparent to.

It is no wonder that in a land where superstition rules the mind and credible medical care is unavailable to the plebs sordida that homeopathy and faith healing should flourish. After all, there are no alternatives. Of course, this sort of stupidity is reinforced by the likes of Deepak Chopra; a man who has one set of spiritual and scientific convictions for those in his homeland but an alternative set for his Western prey.

Beware Indian made homeopathic remedies as they may kill you. Indian water represents some of the most polluted water in the world.

Of course, let us not forget that the famed homeopathic Greek quack "professor" George Vithoulkas was trained in homeopathy in India. Vithoulkas' writings are nearly incomprehensible, always bitter, and reflect a confused, afflicted mind. Search youtube for some of his "teaching" clips and be astounded at how little sense it all makes. Vithoulkas is exactly the type of quality loon that one would expect from an Indian university of quackery.
Unfortunately we all have our scam artists, whether it is the U.S., U.K., Canada, Australia, India, China etc but there is a legal system which does catch and at times punish such scamsters. The enforcement standards vary and we in India are gradually improving the standards of enforcement - aka India is the only country where PepsiCo is being compelled to put a seal of quality assurance "One Quality Worldwide" across all its product labels.

Good Manufacturing Practices have been legislated in India for manufacturing Homeopathic drugs. Homeopathic education is standardised under the relevant legislation. Homeopathic clinical field units and research centres have been set up across the country.

India takes quality in health very seriously - the Courts have stepped in very often on complaints of the public about poor standards in government health facilities - they are being upgraded and improved - re-usable needles are banned/ phased out.

As for the private sector this article from Canada is quite revealing about the high standards achieved in India:

"Medical tourism: Need surgery, will travel
CBC News Online | June 18, 2004
India

India is considered the leading country promoting medical tourism-and now it is moving into a new area of "medical outsourcing," where subcontractors provide services to the overburdened medical care systems in western countries.

India's National Health Policy declares that treatment of foreign patients is legally an "export" and deemed "eligible for all fiscal incentives extended to export earnings." Government and private sector studies in India estimate that medical tourism could bring between $1 billion and $2 billion US into the country by 2012. The reports estimate that medical tourism to India is growing by 30 per cent a year.

India's top-rated education system is not only churning out computer programmers and engineers, but an estimated 20,000 to 30,000 doctors and nurses each year.

The largest of the estimated half-dozen medical corporations in India serving medical tourists is Apollo Hospital Enterprises, which treated an estimated 60,000 patients between 2001 and spring 2004. It is Apollo that is aggressively moving into medical outsourcing. Apollo already provides overnight computer services for U.S. insurance companies and hospitals as well as working with big pharmaceutical corporations with drug trials. Dr. Prathap C. Reddy, the chairman of the company, began negotiations in the spring of 2004 with Britain's National Health Service to work as a subcontractor, to do operations and medical tests for patients at a fraction of the cost in Britain for either government or private care.

Apollo's business began to grow in the 1990s, with the deregulation of the Indian economy, which drastically cut the bureaucratic barriers to expansion and made it easier to import the most modern medical equipment. The first patients were Indian expatriates who returned home for treatment; major investment houses followed with money and then patients from Europe, the Middle East and Canada began to arrive. Apollo now has 37 hospitals, with about 7,000 beds. The company is in partnership in hospitals in Kuwait, Sri Lanka and Nigeria.

Western patients usually get a package deal that includes flights, transfers, hotels, treatment and often a post-operative vacation.

Apollo has also reacted to criticism by Indian politicians by expanding its services to India's millions of poor. It has set aside free beds for those who can't afford care, has set up a trust fund and is pioneering remote, satellite-linked telemedicine across India."
 
Well, yes. Homeopathic procedure.



Yes, we are testing the remedy, because the only difference between the placebo group and the verum group is that the latter receives remedies.

Both groups are subjected to the "homeopathic procedure". So, if there is a difference, it must be due to a property of the remedies. If there is no difference, the conclusion is that the remedies have no properties different from placebo.

And yes, one of the claims of the skeptics is that homeopathic remedies equal placebo.



I still fail to see the difficulties. Admitted, a properly conducted trial, with individualized treatment, will be fairly complex. More complex than a single drug trial, but there are certainly no insurmountable problems.



A properly designed and executed double blinded, randomized, placebo controlled trial of homeopathy with a positive result would be considered important evidence that there is reason for further research.

The reason for this rather reserved position is that IF homeopathy works, a considerable part of present science will have to be revised, thus overthrowing the very solid body of evidence that exist for it. Therefore, such a revision will require extremely strong evidence (remember, even a statistical 99% confidence still leaves a 1% possibility of a spurious result)

Therefore, I don't think a single trial result, even if well conducted, will immidiately convert the scientific world in favor of homeopathy. It will, however, no doubt motivate further serious research. And it will certainly open the door to widespread publication.

Hans
Valid point.
 
Yes. And that is one of the main criticisms of homeopathy - that rather than measuring true cures, they measure "cure" only by symptom suppression.



We have made no requirements for the material presence of the drug. And both individualized and single treatments are amenable to the kind of study that allows us to remove the effects of chance and wishful thinking.



Yes. These are exactly the kinds of results one would expect if homeopathic treatments have no real effect.

Linda
Symptom suppression!!! Apparently you have no knowledge of homeopathy.

Homeopathy individualizes treatment based not only on symptoms - in addition to symptoms a homeopath needs to consider mentals, generals, pathology and sometimes genus epidemicus.
 

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