I think we're also faced with a political and social issue, which is the idea that one's very life, and quality of life, is threatened when certain choices are threatened: the quintessential myth of the free American, the rugged individual. This is not consistent, of course. People who resist vaccines and masks, and whatnot, are unlikely to see a parallel in the requirement to wear shoes in the grocery store, or to stop at stop signs, or other familiar and traditional compromises with society. But it takes a bit more insight to cope with novelty, so when a new social obligation comes up, people balk, and suddenly consider that their very existence as free Americans is negated, their very life threatened.
Of course individual choices often have public impact, and even most of those now resisting Covid measures probably see some validity in rules like requiring children to go to school, and requiring that their teachers wear clothes, or that grocery stores post prices, or that we don't settle arguments by beheading our opponents, and so forth. But, bolstered by bad science and political nonsense, they see no parallel in the idea that in the midst of a pandemic you should not be free to ignore the disease and spread it mindlessly, not be free to invent your own personal truth.
We see the libertarian myth in threads like this, where people who adhere to the public weal are sheep. The superior folks go their way, swinging their figurative sabres as they saunter down the street. Watch out, sheeple, here comes the herd-master.
