Correction... they have to satisfy almost ALL the republicans... if a couple are otherwise indisposed, or if a couple decide that the nominations by an incompetent racist orangutan are bad for the country and actually decide that treason is not cool, and none of the democrats vote with them, some of these appointments could be lost.
Devos was confirmed by only a vote of 51-50, and that was with a senate that had 1 more sitting republican. Now things are even tighter, and a few republicans who are facing re-election may decide tying themselves to a treasonous white house may hamper their campaigns.
Gorsuch is a perfect example. Trumps judges will do fine.