Would be interested in hearing Blutoski's thoughts on this
http://www.salon.com/2015/04/12/you_should_never_diet_again_the_science_and_genetics_of_weight_loss/
In particular the prison experiment and the conclusions the author draws from it.
I'm looking forward to reading the book.
Regarding the prison studies: I'd have to read the actual papers. I expect there are citations in the book. They're saying they fed subjects 10,000 calories per day for months and prohibited exercise, but saw no change in body fat percentage. Sounds improbable at face value, and I'd like to read the material. I'd be curious about wastage, for a start. Meaning: they could have been
offered 10,000 calories per day, of which they ate as much (or as little) as they chose, and may have maintained body fat percentage that way. We're talking prison food here, I probably wouldn't eat more than I absolutely had to. And it could be a demonstration of environment's effects that way as well, rather than genetics per se.
Other experiments have been conducted that have similar goals and structures, volunteers who are not prisoners, and the results were different. So it'd be interesting to identify whether there was a systematic confounder with these.
The author does work with the Minnesota Twin Study database, and I've noticed those guys have a bias toward genetics and tend to gloss over the database's primary weaknesses. Specifically selection bias - the less similiar twins are, the less they get along. The ones that don't get along don't join or continue with the study and don't have much impact in the database. There is an uncorrected selection bias toward similarity.
However: the percentage the author reports (70% genetic predictability) is consistent with other analyses.
So for the most part, I'm in pretty good agreement. We have biological predispositions that at in an environment. (not the least of which is that we are drawn to eat sugar, fats, salt) The environment has changed over the last X years to become more obesogenic. Ergo we have become more obese. No argument there.
The author also advises against 'dieting' and off-limits foods &c, and that's my stance as well, although it becomes semantics a bit. Lifestyle changes with an eye to sustainability seem to be the recipe for weight management success.
Here's where I think I diverge a bit: my compromise regarding 'dieting' is that since fullness is not entirely dependent on calories, there are opportunities to eat 'less' and not go into the starvation-obsession mode she describes in the conclusion. As mentioned above, finding recipes that goose up the grams of fiber/water at the expense of fat, sugar/starch, and ethanol does seem to reduce the incidence. As is creating realistic rates of fat loss. No lentil soup recipe will salvage a 1000 calorie day. Secondly, I think the author's article is probably skimming what must be a richer discussion of environmental management.
So, not sure what to make of it without really reading the book, but worried that the author may unintentionally fall into the trap that a lot of geneticists do: accidentally give readers the impression that genetics have power outside our environment.