Simulations require accurate descriptions of the physical process you are trying to model. Without that, all the simulations in the world won't tell you anything.
The point of all this is that a simulation is only as good as the model it uses. If the model is wrong, your simulation will be wrong.
In order to have an accurate model, you must investigate the real object in extreme detail - which eliminates some of the advantages (savings in time and effort) you would hope to have from the simulation.
all models are wrong, so all simulations are wrong in that sense. but i would agree you need observations to see if the model is of any use. we do not "accurate descriptions of the physical process" to build weather models, but we have lots of forecasts and corresponding observations to learn how to use the models.
but in seasonal forecasting, for example. we really only have 20, maybe 40 years of good observations on which to run/test our models. and those tests are all in-sample (we used insights from those years to build the model. our models have 10^7 degrees of freedom and thousands of parameters to be specified.
all with 40-ish data points...
i bigger computer would help a lot; a little more understanding would go a long way too. but even with both, it will take time to verify whether or not we have made real improvements.