No, we are not, because none of us know what "human nature" is.
If you think so, what did you mean to say by referring to "people trying to reconcile human nature with religious doctrine"?
The vast majority of suffering has been caused by the dominance hierarchies of society.
So much for disaster, disease, and the thousand natural shocks that flesh is heir to.
Don't the vast majority of effective efforts to alleviate suffering of all sorts also depend to a significant extent on the "dominance hierarchies of society"?
As the most prevalent one in human history, organized religion must bear the brunt of criticism directed at such entities.
First, what do you mean by most prevalent (for it has rarely been the most dominant)? Second, why can't we critique such entities on their own merits? Why why would we attribute to some "dominance hierarchies" vicarious liability for the acts of other ones?
You might be able to argue that religion is the least damaging of the dominance hierarchies, but you cannot offer any evidence that religion abates or mitigates the consequences of "human nature," because "human nature" has for thousands of years been the learned behavior of setting up and operating within dominance hierarchies like organized religion.
It makes no more sense to me to lump all religions together than it does to lump all "dominance hierarchies" together. But my point was that certain religious doctrines are directly or indirectly concerned with mitigating suffering, and I think it is clear that that the existence, promulgation and pursuit of such doctrines actually has achieved that result in many instances.
Still waiting to hear your view of which major advancements in human didn't contribute ad majorem dei gloriam, and how they were all opposed by the Church.