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Stem Cells & Healing?

Ixion,

Thanks for detailed explaination.

Healing is explained here;-

http://en.wikipedia.org/wiki/Healing

However stem cells involvement in this process of healing, can be important to understand. They should be involved in clearing the wound, repairing & replacing the injured/damaged tissues.
 
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Kumar said:
Ixion,

Thanks for detailed explaination.

Healing is explained here;-

http://en.wikipedia.org/wiki/Healing

However stem cells involvement in this process of healing, can be important to understand. They should be involved in clearing the wound, repairing & replacing the injured/damaged tissues.
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Kumar, stop pretending you understand the explanations. You don't.

Hans
 
Complexity said:
Kumar is a homeopathy troll.

I, for one, do not welcome him back.
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These were the good words I read sometime back on pubmed:-

"One who can't do or don't want to do should not interfere in other's doing"
 
Kumar said:
Mr Hans, you also stop pretending that you can explain it. This is not your field.
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Exactly where did I even attempt to explain anything in this topic?

You are not even a good liar.

Hans
 
Kumar said:
These were the good words I read sometime back on pubmed:-

"One who can't do or don't want to do should not interfere in other's doing"
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Nice. Now Kumar, what have you EVER done except wasting other people's time? All you ever do is come in, ask stupid questions, and ignore or misinterpret the answers.

Hans
 
Kumar said:
My basic questions are:-

1.Can antiinflammatory interventions by NSAIDs, steriods(anti-microbials & antioxidants?) interfere in normal stem cell activities?

2.Does compromising or weaking of stem cells activities related to weaking of immune & healing system?

3.How this system is weakened or compromised?

4. Whether weakening or compromising of stem cells activities result into compromised healing eg. scar formations, fibrosis etc.?

5. What are the factors which can cause weakening or strengthing of stem cell system?
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Before I bother to waste my time with these question, as I know your infamous posting history, which take about...a few minutes of googling to do...why do you want to know?
 
MRC_Hans said:
Exactly where did I even attempt to explain anything in this topic?

You are not even a good liar.

Hans
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Then simply read & learn but avoid stop doing others if you can't do or don't want to do.
 
MRC_Hans said:
Nice. Now Kumar, what have you EVER done except wasting other people's time? All you ever do is come in, ask stupid questions, and ignore or misinterpret the answers.

Hans
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When you don't know about a topic, you can't evaluate & comment.
 
paximperium said:
Before I bother to waste my time with these question, as I know your infamous posting history, which take about...a few minutes of googling to do...why do you want to know?
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It is not wrong to have additional knowledge. Moreover anyone can need it.
 
Stem cell niche is a phrase loosely used in the scientific community to describe the microenvironment in which stem cells are found, which interacts with stem cells to regulate stem cell fate. The word 'niche' can be in reference to the in vivo or in vitro stem cell microenvironment. During embryonic development, various niche factors act on embryonic stem cells to alter gene expression, and induce their proliferation or differentiation for the development of the fetus. Within the human body, stem cell niches maintain adult stem cells in a quiescent state, but after tissue injury, the surrounding micro-environment actively signals to stem cells to either promote self renewal or differentiation to form new tissues. Several factors are important to regulate stem cell characteristics within the niche: cell-cell interactions between stem cells, as well as interactions between stem cells and neighbouring differentiated cells, interactions between stem cells and adhesion molecules, extracellular matrix components, the oxygen tension, growth factors, cytokines, and physiochemical nature of the environment including the pH, ionic strength (e.g. Ca2+ concentration) and metabolites, like ATP, are also important. The stem cells and niche may induce each other during development and reciprocally signal to maintain each other during adulthood.
http://en.wikipedia.org/wiki/Stem_cell_niche
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Above look to be quite interesting to me to find awnser to my questions. Can you add?
 
The role of oxygen availability in embryonic development and stem cell function
M. Celeste Simon & Brian Keith

Abstract
Low levels of oxygen (O2) occur naturally in developing embryos. Cells respond to their hypoxic microenvironment by stimulating several hypoxia-inducible factors (and other molecules that mediate O2 homeostasis),
http://www.nature.com/nrm/journal/v9/n4/full/nrm2354.html

Oxygen control of stem cell niches and cell fates
Posted by attilachordash on April 2, 2008

Did you know that physiological normoxia generally falls in the 2-9% O2 (14.4-64.8 mm Hg) range for most adult cells in vivo? 3 remarkable exceptions are thymus, kidney medulla and most importantly bone marrow which can exist at 1% O2 (7.2 mm Hg). On the other hand, stem and progenitor cells are frequent residents of hypoxic niches and low O2 regulates their differentiation. Conclusion?
http://pimm.wordpress.com/2008/04/02/oxygen-control-of-stem-cell-niches-and-cell-fates/
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Above quotes can also be interesting in finding the awnsers.
 
MRC_Hans said:
Let me translate this for you all: Kumar wants to know if stem cell thory can be used as an argument for homeopathy, and aurvedic medicine and to show that conventional treatment for diabetes is flawed.

He has therefore googled some stuff, but cannot understand more than 1/3 of the words in it, so he wants us to provide him with nicely digested information, which he can then cherrypick and distort so he thinks it supports his ideas.

Been there, done that, bought the T-shirt.

Oh, and: Hi Kumar!

Hans :rolleyes:
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HAha, thanks. I honestly couldn't even figure out what was being asked.
 
Kumar said:
Above look to be quite interesting to me to find awnser to my questions. Can you add?
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I can add.

Homeopathy is fraud. It's dangerous and potentially deadly in that patients might die because they do not seek out real medical attention.

Ayurvedic medicine is fraud. It's dangerous and potentially deadly, not only in that patients might die because they do not seek out real medical attention, but also in that the medicines themselves can be poisonous.

Both are entirely without scientific basis and are promoted only by the supremely ignorant and the criminally negligent.
 
Also, India has some of the worst healthcare statistics of any country. Kumar, I'll give you three guesses as to why.
 
PixyMisa said:
Ayurvedic medicine is fraud. It's dangerous and potentially deadly, not only in that patients might die because they do not seek out real medical attention, but also in that the medicines themselves can be poisonous.
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It is also, with its use of the concept of humours (called "doshas" in Ayurveda), far closer to the Hippocratice medicine that Hahnemann derided as "allopathic" than anything in real medicine nowadays. Although not as close as "Unani", which is administered by the same Indian governmant department as homoeopathy and Ayurveda and is explicitly based on Hippocratic "allopathy".
 
Yep, it's not fundamentally nonsensical the way homeopathy is, it's just untested, unscientific, and potentially lethal.
 
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