Questions about Diabetes?

My observation & logics indicate it accordingly. Moreover, real /basic cause ti IR is not yet known ALSO reducing or discontinuing of medications are also not yet clinically tried.
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He just continues to make up "the facts" as he goes along, folks.
 
Kumar said:
"The body manufactures insulin to transport sugar (glucose) into cells so they can use it for energy. Obesity worsens insulin resistance, making it increasingly difficult for cells to respond to insulin. The body reacts by releasing more insulin to "override" the insulin resistance."

Exactly. Thus: IR is the cause of high insulin production, not the other way around.

Hypo shots may be after when insulin & glucose can be fully used by cells & then no furthur glucose is available.

Hypo episodes happen when the BG for whatever reason falls below a certain level.

I am not sure whether hypo shot can also be experianced as glucose not used due to IR/Over IR condition?

No. That does not gove a hypo reaction.

Anyway in IR condition both BG & insulin can be excessive, still hypo shots are not experianced.

Of course not, since BG is high.

I think hypo shots can also be dependant on 'how cells are able to take sugar other than how much sugar in available'.

But you are wrong. Hypoglucheamic episodes means that BG is LOW, and the characteristic symptoms of a hypo come only in that situation.

I think in IR excess insulin as well as excess glucose is there.

Yes, early in the developement of type 2 that is the case (as we have discussed endlessly). This is because the body reacts to the glucose starving of the cells by "shouting"; it raises BOTH insulin and BG levels, in order to force glucose into cells. This is the correct and only survival strategy the body has, but unfortunately it has adverse long-term effects.

Occasional Exposure of insulin in large amount to cells can make them bored and unwilling to take more glocose & insulin effect. If we eat more & iregularily, the digestive secretions can be said to be necessary but still imbalanced/excessive & so can cause progressive damages.

No, despite extensive research, we have no indication that this should be the case. The progression of IR is indeed lifestyle dependent, but the important factors are dietary lipids (fats), overweight, hypertension, smoking, and lack of exercise.

To my knowledge, an excess consumption of sugar has not been observed to lead to diabetes, except through overweight (which is an indirect effect).

It may depend upon predisposition of a person/constitution.

Yes, there might be some isolated cases, we can never know that. But it is not a general mechanism.

How did you get the idea that excess insulin can lead to IR and why do you want it so badly to be true?

My observations & logics indicate this concept accordingly.

Which observations?

Moreover, real /basic cause to IR is not yet known.

That does not mean that any daft idea has merit.

ALSO by reducing or discontinuing of medications are also not yet been clinically tried.

It has certainly been tried in practice. Plenty of cases are on record where patients discontinued medication for one reason or the other. There are parts of the world where patients often have to choose between buying medicine or food. The results are always the same: High BG and irreversible long-term damages :(.
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Hans
 
MRC_Hans said:
Exactly. Thus: IR is the cause of high insulin production, not the other way around.

It can be a vicious circle.

I am not sure whether hypo shot can also be experianced as glucose not used due to IR/Over IR condition?

No. That does not gove a hypo reaction.

Can it give sudden severe hypo reaction at some long intervals?


Yes, early in the developement of type 2 that is the case (as we have discussed endlessly). This is because the body reacts to the glucose starving of the cells by "shouting"; it raises BOTH insulin and BG levels, in order to force glucose into cells. This is the correct and only survival strategy the body has, but unfortunately it has adverse long-term effects.

Since,IR condition raises BOTH insulin and BG levels or excess of ANY or BOTH of insulin and BG levels may lead to IR--can't be decided. Do the other hormones also become resistant as IR?

No, despite extensive research, we have no indication that this should be the case. The progression of IR is indeed lifestyle dependent, but the important factors are dietary lipids (fats), overweight, hypertension, smoking, and lack of exercise.

These are not universal factors. These factors can lead to high insulin secretions & so probably progression of IR.

Which observations?

I personally observed in few cases as I indicated previously.

It has certainly been tried in practice. Plenty of cases are on record where patients discontinued medication for one reason or the other. There are parts of the world where patients often have to choose between buying medicine or food. The results are always the same: High BG and irreversible long-term damages .
In view of consideration risk involvements, it has not yet been clinically tried. Can you give me some referances?

Furthur, I am not sure but I think these is some link with low total cholesterol level & persistance og high BG levels. Do you have any idea that it is easy top control BG level if TC are bit higher but difficult if TC are lower say 100-140 mg/dl?
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Can you give me some referances?
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Kumar, can you give us some references to prove that homoeopathy works?

Why do you dismiss Hans' anecdotal evidence regarding the effects of discontinuing diabetes medication (which are a lot more mass observed than any effect of homoeopathy, let me tell you), but expect us to give credence to your even more hazy anecdotes?

Rolfe.
 
Rolfe: *SLAP!*

(You asked us to slap you if you fell to the temptation to join again ;)).

Kumar: None of your last arguments have merit. Go directly to jail, don't pass GO, don't collect 10$. .... Seriously, I'm giving you factual information; use it or not, I don't give a damn.

Hans
 
Ok, let us leave it as we don't want to think & understand an unclear aspect differantly & just want egoistic contradictions. We can read tons of regular informations available on internet, then why to waste each others time.:o
 
Kumar said:
Ok, let us leave it as we don't want to think & understand an unclear aspect differantly & just want egoistic contradictions. We can read tons of regular informations available on internet, then why to waste each others time.:o
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No, Kumar. You deliberately refuse to understand a perfectly clear aspect and just want egotistically to follow your own agenda.

Carry on, but don't expect people who really do understand it to follow you.

Rolfe.

OK Hans, you can slap me again.
 
Mr.Hans, Rolfe,

If you say so, please tell me the real & basic cause of getting insulin resistance. What is the relation of low total cholesterols & BG levels? What is the relation of Sulphur with diabetes in view of both diabetic oral medicine & insulin's one constituent is Sulphur?
 
Kumar said:
Mr.Hans, Rolfe,

If you say so, please tell me the real & basic cause of getting insulin resistance. What is the relation of low total cholesterols & BG levels? What is the relation of Sulphur with diabetes in view of both diabetic oral medicine & insulin's one constituent is Sulphur?
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No reply!!

It was told to me that:-

"When target cell become loaded with excess glucose, they do start down-regulating the number of insulin receptors on their surfaces. & they behave just opposite when cells become normal or deficient to glucose exposure"

What you can add to it?
 
The amount of cortisol present in the serum undergoes diurnal variation, with the highest levels present in the early morning, and lower levels in the evening, several hours after the onset of sleep. Serum cortisol levels fluctuate in response to a number of other variables, including ACTH levels, psychological stress, and such physiological stressors as hypoglycemia, illness, fever, trauma, surgery, fear, pain, physical exertion or extremes of temperature.

Cortisol is usually released in response to long term stress. Some effects of cortisol being secreted into the bloodstream are an increase in blood pressure and glucose concentrations. Also it increases the glycogen formation in the liver. (Freeman, 853) The release of cortisol inhibits functioning of the immune system, and bone formation.
http://en.wikipedia.org/wiki/Cortisol
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Cortisol looks to be important homone related to BG levels. Can you add some more information to it?
 
Kumar said:
"When target cell become loaded with excess glucose, they do start down-regulating the number of insulin receptors on their surfaces. & they behave just opposite when cells become normal or deficient to glucose exposure"

What you can add to it?
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As part of the many processes in NIDDM down regulation of insulin receptors occurs. You have to have a much beter grasp of the basic processes than you have or have been willing to acquire to place it in context.
 
Kumar said:
Cortisol looks to be important homone related to BG levels. Can you add some more information to it?
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Adrenal corticosteroids have a huge range of effects among which is a tendency to raise blood sugar, but unless you want to get a better grasp of the basics that have been presented to you previously there is no point in discussing this further.
 
BSM, previous discussions were lost in this & that types of talks. You may tell now some usefull informations.

Cortisol levels are related to Cushing syndrome (too much cortisol, obesity, muscle wasting, and muscle weakness) and Addison disease (too little cortisol, weakness, fatigue, increased pigmentation, among others), two serious adrenal disorders. Cortisol levels may also increase as a result of hyperthyroidism or obesity & Hypothyroidism may decrease cortisol levels. It is synthesized from cholesterol.
 
Try a good hot cup of tea, Kumar, then a drive down to the seaside. That should do the trick!

What? This isn't relevant to your discussion? Well, neither is your drivel in this and other threads, but I thought I'd stick with you method of discussion so you didn't feel lonely.
 
Zep said:
Try a good hot cup of tea, Kumar, then a drive down to the seaside. That should do the trick!
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I do not 'manipulate in driving' & want to remain natural. Do you have any knowledge to contribute?
 
Badly Shaved Monkey said:
Sulphur is an atom that is part of several amino acids. End of story.
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That is common understanding that Sulfur Containing R-Group a.a Cysteine, Methionine are there. But, what are their role & relation to diabetes? What is the role of disulfide bonds in insulin? Is sulphur freed on insulin usages?

"Glutathione concentrations in liver and lung fall when food intake or sulphur amino acid intake is inadequate. However, concentrations may be restored during inflammation, despite anorexia, provided that prior sulphur amino acid intake is adequate."
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9093011&dopt=Abstract

??
 
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