4. More importantly, for me, was the question not raised, which seems to be coming up these days: at what point do we start deliberately and selectively breeding people for certain traits? We do it with animals of many sorts: dogs, cows, horses, cats. We do it with plants.
Socially, if not scientifically, any number of "desirable traits" inform the general breeding process. Smart. Pretty. Healthy. Fast. Strong. Nice hooters. Agile Whatever.
What list (and it would be thousands of items long, given the need for resistance to diseases and various syndromes and birthdefects) of attributes would a human need to be bred for to place its potential (still has to be raised and potential tapped) in the second and third standard deviation from the mean? the fourth? The fifth? (For whoever answers "one from Column A, two from column B," on the list, I'm a step ahead of you.

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How many generations would it take to move the mean one, two, or three standard deviations to the right? For all humans?
For the record: I am not a huge of all the thinking behind 4. That said, look at what pre natal procedures have developed into, and how invitro procedures allow a certain amount of discretion over "the old fashioned way." See also the use of so primative a technology as ultrasound to inform decisions to abort female fetuses (some news on that in the past decade, China and India). Hee hee, in twenty years, how are they gonna get a date? I can see it now: The Sex Wars, and the root causes of the Great Chinese Civil War.
I don't see there being some invisible barrier beyond which humans won't advance to gain greater control of the outcomes of the reproductive process. (Me, I'm all for getting a little wine, taking the missus out into the hills, and the two of us going at it under a full moon, but I wouldn't insist that a control freak feel bound to that regimen.)
The vulnerability to discrete diseases found in the Askenazim study h8ighlights, at least to me, one of the many hazards of pursuing the path of genetic manipulation.
DR