Actually, in most cases I can show a 90 pound woman how to handle a situation with a 200 pound attacker, yes. Lack of imagination isn't an excuse.
And this is why I advise women to never take a 'women's' self defense class; stuff like this actually gets believed.
The only true defense there without a weapon is to run. Yes, you might have to make some mai before you can effectively run and that is where tactics like the foot stomp, eye gouge, and balls kick can come in handy. However, that doesn't mean that the 90 pound woman is 'safe' and the overconfidence that comes from training only with other women is dangerous.
Every time I've trained with women they have been seriously surprised that their defensive tactics didn't work. I'm a big guy, and all of the stagger moves do just that, if anything. The real surprise comes when these women are shown that not only does stomping on my foot and elbowing me in the forehead only stop me for a split second, but I can outrun them as well. I'm not even exceptional.
Make distant, get help. Otherwise, no, you're not going to 'win' in a fight against a much stronger opponent.
I've never been in a match with a woman who posed much of a threat to me, and that includes the blackbelts. Even the 150lbs women get physically dominated. I'm sure there are women out there who could easily kick my ass, but that doesn't mean women can learn a few 'moves' and be 'safe'.
On a side note, the 'a man kicked in the balls is defenseless' is one of the biggest myths out there. Not only is it not very easy to hit there in the first place, but a lot of men just get very pissed off from the pain.
EDIT: I should add that this really doesn't have much to do with guns, but that women's self defense has more to do with cell phones and being aware than with moves, guns, or mace. Just don't think you can take on someone a lot bigger than you.