Study
The setting was 120 adult patients attending a cardiac rehabilitation clinic after bypass surgery or myocardial infarction, and taking simvastatin or atorvastatin. The only exclusions were inability to read or where first language was not English.
There were two variables. Two different adverse events of statins were chosen, constipation and pancreatitis, and the adverse event information was presented using words or numbers (Presentation Box below), using EU guidelines (Table 1). Half of the participants received information about constipation, and the other half information about pancreatitis (atorvastatin users only). Within each group, half received the information using words, and half using numbers. Allocation was random.
Results
The age range of participants was 35 to 74 years (median 63), and they had been taking a statin for one to 70 months (median six). The majority (56%) had no formal educational qualifications.
For both constipation and pancreatitis, participants overestimated the percentage chance of the adverse event affecting them (Figure 1). The degree of overestimation was far higher using words than using numbers. Using words rather than numbers also increased patient estimates of the event happening to them using a six point scale, with small differences in some other questions, and satisfaction with information presented was somewhat higher with numbers than with words.