A common misconception about HFCS is that it is sweeter than sucrose and that this increased sweetness contributed to the obesity crisis by encouraging excessive caloric food and beverage consumption. HFCS is not sweeter than sucrose. The sweetness of several common nutritive sugars in crystalline and liquid or syrup form is compared in
Table 2.
Sweetness intensities of crystalline compounds were reported in pioneering work by Schallenberger and Acree in 1971. They determined that fructose in the crystalline, β-d-fructopyranose anomeric form has
1.8 times the sweetness of crystalline sucrose; the relative sweetness of crystalline glucose is lower at 0.7–0.8. Note that the sweetness of HFCS cannot be determined in crystalline form because HFCS does not crystallize.
It is this marked difference in sweetness between fructose and sucrose in crystalline samples that is often confused and inappropriately attributed to HFCS, a blend of equal amounts of glucose and fructose in liquid or syrup form.
Once in solution, β-d-fructopyranose undergoes rapid mutarotation to give a mixture of several tautomers with lower and differing sweetness intensities. White and Parke reported the sweetness values of liquid and syrup samples relative to the sucrose standard as established by trained, expert food industry taste panels.
In syrup form at 10% solids (the approximate sweetener concentration in most carbonated beverages), HFCS-55 and sucrose yield the same relative sweetness. Under the same experimental conditions, HFCS-42 is less sweet than sucrose, with a value of
0.9.
In 2000 Schiffman et al reported the absolute sweetness of syrups at various concentrations and temperatures. The HFCS absolute sweetness value reported in Table 2http://www.ajcn.org/cgi/content-nw/full/88/6/1716S#T2 was calculated by regressing Schiffman's data for fructose and glucose to 10% solids and then substituting the resulting values into the known compositions of HFCS-55 and sucrose. Using sucrose once again as the standard by setting its sweetness equal to 100, a sweetness value of 97 was calculated for HFCS-55, providing independent validation for the value reported by White and Parke. Schiffman's work also confirmed the earlier work of Hyvonen et al and White that temperature has little effect on sweetness intensity. These data confirm what the food industry has claimed for more than 20 y: the sweetness intensities of HFCS-55 and sucrose are equivalent. The replacement of sucrose by HFCS-55 did not change the sweetness intensity of foods and beverages, nor did it lead to a "sweetening of America"