Oh, I think that's all true: the problems of interstellar travel, while I think they are soluble, are orders of magnitude greater than, for instance, global warming.
My suspicion is that they are not solvable or if they are solvable civilizations are destroyed before there is much interstellar travel.
1. Fermi's paradox kind of makes sense to me here. If interstellar is possible where are the little green men? OK, it's not a proof but there's been a lot of time for the little green men to build their space ships and visit us, so far they've left no evidence that they were here but maybe they've been here and the evidence was destroyed I suppose
2. Even if limited interstellar space was possible I'm not sure that a civilization is going to put the resources into blasting a very few people into the great unknown for perhaps multiple generations.
3. Long term exposure to space radiation looks like it might be a difficult problem to solve. I could envision some giant space ship surrounded by a massive water and lead barrier. That might help with the pesky problem of any tiny particles hitting the ship with massive kinetic energy and blowing huge holes in it. But the need for thick heavy radiation shielding will substantially increase the resources required for this venture and that already looks like a major stumbling block.
4. My guess is that at least some of amb's pessimism is well placed and the goldilocks type planets are uncommon and there just may not be one near enough to us to get to in even a few generations.
Still as I wrote this I was kind of amazed by all the things I don't know about the future and the unpredictable ways things might go. Maybe people end up with greatly lengthened lives and traveling through space for a few hundred years seems like an ok thing to do, Maybe mass launchers turn out to be pretty easy to do and getting big chunks of stuff into space isn't that big a deal. Maybe the giant space based planet hunting telescopes get built and people learn enough about a target planet some place that finding a planet with conditions adequate for human life becomes possible.
Or maybe we just kill ourselves before any of this stuff becomes possible in some massive nuclear exchange.
I'm old enough that I don't expect to have gained much insight as to the viability of any of the technology needed for interstellar space before I breath my last breath. Maybe some of the youngin's in this forum might get a glimmer of insight in their lifetimes, but I'm pretty sure none of them will live to see somebody blast off for another star in their lifetimes either.