Fibromyalgia- Lab test! and a Vaccine!

Skeptic Ginger said:
You pay for the screening lab work.

You ask for a physician diagnosis and you list the criteria for the diagnosis.

Those would be typical ways of recruiting volunteers.
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You don't have to join the study if you don't want to get the test. The test has been out for a while, they can recruit from people who've already taken the test.
 
Skeptic Ginger said:
Here's how a valid study works. This is a RCT using BCG that is in phase 2 but not yet recruiting:

Phase II Clinical Trial: Multi-dosing the BCG Vaccine for Fibromyalgia

I didn't search through the 193 open studies to look for the one with the company selling $1,080 lab tests.
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EpicGenetics is the company selling the $1,080 lab tests. Isn't this their study? If it isn't though, this study you are citing as valid has the same inclusion criteria that you said made the "other" one invalid.

And you mentioned a study that started in 2018, what study is that?

https://www.precisionvaccinations.c...ctive-both-diabetes-and-fibromyalgia-patients
https://www.biospace.com/article/-c...spital-to-launch-fibromyalgia-clinical-trial/
 
casebro said:
That is EXACTLY the study from the OP. It doesn't even start until 2022.
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Phase 2 doesn't start, phase 1 isn't mentioned in that entry.

I also note the lack of a requirement to pay for a $1080 lab test.

In addition I find it suspicious the lab claims to have a special test for fibro but describe it as a certain combination of tests.

You said it was patented. I wonder how one patents a combo of tests that are otherwise not patented. Do you have any more information on this combo?
 
casebro said:
Well yeah, before they do a study they will want subjects that do have the disease. There is only one test for FM. How would you expect them to recruit?
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Is there really a test? Because it's my impression that the disease is diagnosed from a lack of results from other tests.

In fact I'm not sure they really know what the disease is, so how can they test for it?
 
RecoveringYuppy said:
EpicGenetics is the company selling the $1,080 lab tests. Isn't this their study? If it isn't though, this study you are citing as valid has the same inclusion criteria that you said made the "other" one invalid.

And you mentioned a study that started in 2018, what study is that?

https://www.precisionvaccinations.c...ctive-both-diabetes-and-fibromyalgia-patients
https://www.biospace.com/article/-c...spital-to-launch-fibromyalgia-clinical-trial/
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The OP cite says they approached Mass General who is doing at least the phase 2 part of the test.

I don't see any requirement for the lab work listed on the Clinical Trials site.

2018 was the date on the OP article.

The Mass Gen study looks perfectly legit. The OP cite is where I find things that are red flags.
 
Skeptic Ginger said:
The OP cite says they approached Mass General who is doing at least the phase 2 part of the test.
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Right, read the OP link and then read at least the headline of the second link I just cited. MGH is where the Phase 2 trial we are discussing is going to happen as far as I can tell.
 
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Belz... said:
Is there really a test? Because it's my impression that the disease is diagnosed from a lack of results from other tests.

In fact I'm not sure they really know what the disease is, so how can they test for it?
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There is a test. It's called FM/a (I believe that's already been cited). It's produced by a company called EpicGenetics. I'm not exactly sure what it's status is, it's apparently not generally accepted. They are (maybe were at this point) working with the Mayo Clinic and University of Illinois College of Medicine. I'll find some links I saw earlier.

Mayo Clinic Link
Pub Med article from 2012
 
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Link to patent abstract:L https://patentscope.wipo.int/search/en/detail.jsf?docId=WO2012051317

Fig 1 graphs rates of cytokines: IL-10, mip-1b, mcp-1, mip1-a

Also, from else where re: the data on which the patent is based:

In December 2012 ‘Unique immunologic patterns in fibromyalgia’ was published as Behm et al. BMC Clinical Pathology 2012, 12:25 http://www.biomedcentral.com/1472-6890/12/25. The authors measured cytokine levels in the blood of 201 subjects (110 with fibromyalgia). They concluded ‘The cytokine responses to mitogenic activators of PBMC isolated from patients with FM were significantly lower than those of healthy individuals, implying that cell-mediated immunity is impaired in FM patients. This novel cytokine assay reveals unique and valuable immunologic traits, which, when combined with clinical patterns [italics mine], can offer a diagnostic methodology in FM.’
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(What is "PBMC"?) eta: A peripheral blood mononuclear cell (PBMC) is any blood cell having a round nucleus such as lymphocyte, monocyte or a macrophage. These blood cells are a critical component in the immune system to fight infection and adapt to intruders. /eta ..........so FM is caused by something the body does not fight? And TB vax triggers the body to fight it? I wonder what "it" is? Some kind of TB Lite?

So how bonafide is biomedcentral.com ?
 
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Are there other vaxs that also prevent un-targeted diseases? I think anydamn vax helped fight covid?
 
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