The first thing to do is determine the meaning of "High Crimes and Misdemeanors", so what it meant to the writers of the US Constitution.
Form most sources I have located, these are not actual crimes and violations of specific statues as such, but rather term refers back to an English concept which was the mishandling, misuse, or abuse of the powers of a high office.
Under this, then the question becomes, did the President abuse the powers of his office?
So the next question is, what are the powers of his office?
So under the US Constitution the President is given the power of execution of the Laws created by the Legislature. These laws are to be executed for the public good, i.e. for the good of the country.
So is it a misuse or abuse of power to use those powers for self promotion and gain?
The writers of the Constitution answered this one quite emphatically, yes it is.
Thus the next questions are;
1) Is getting a foreign Government to investigate your political opponents an action that is for personal gain?
2) Did Trump use or attempt to use the powers of the Executive and the State Department to force the Ukraine to investigate Biden?
3) Is such use of Executive Power and the mechanisms of the State Department for self gain a misuse of power?
I think that most people would say that 1 and 3 are certainly true, so that leaves question 2.
From the evidence currently on hand, then it does appear that he did, so on the current evidence then yes he should be Impeach, and where the decision to be non-partisan, he should probably be removed as well. However, since there is a powerful partisan split right now, I suspect that while he will be impeached, currently he is unlikely to be removed. This may change is the GOP grows some balls.