I don't know, same reason you use a computer to balance your checkbook? Why not do a lot of stuff with paper and pencil?T'ai said:In that case, why don't you just use the real world? Do a lot of stuff with flys in jars.
Not evolution as a whole, but macroevolution. Whatever macroevolution is, there is not enough time for it to happen, because Ev's simulation of 1/1000 of 1% of the evolutionary landscape shows that it can't happen in the unspecified timeframe of punctuated equilibrium. Something like that.Level said:So let me get this straight, Kleinman is saying evolution is bunk because it is incompatible with certain results of a simulation? That's rich.
That’s a simulation written by evolutionist Dr Tom Schneider, head of computational molecular biology at the National Cancer Institute and peer reviewed and published in the Oxford University Press journal Nucleic Acids Research. The java version of the program is available online and was written by Moderator Paul Anagnostopoulos. Paul is an excellent java programmer but we have got to work on his arithmetic.Level said:So let me get this straight, Kleinman is saying evolution is bunk because it is incompatible with certain results of a simulation? That's rich.
You almost got it right. This is a three trick pony. Ev shows that huge populations do not markedly accelerate evolution by random point mutations and natural selection. Ev shows that evolution by random point mutations and natural selection is far too slow for punctuated equilibrium as described by Stephen Gould to be mathematically possible. Ev shows that macroevolution by point mutations and natural selection is mathematically impossible.Level said:So let me get this straight, Kleinman is saying evolution is bunk because it is incompatible with certain results of a simulation? That's rich.Paul said:Not evolution as a whole, but macroevolution. Whatever macroevolution is, there is not enough time for it to happen, because Ev's simulation of 1/1000 of 1% of the evolutionary landscape shows that it can't happen in the unspecified timeframe of punctuated equilibrium. Something like that.
With sufficient computing resources, you could run Ev with huge populations and determine how many generations are required. Neither you nor I have run Ev with any more than about 128,000 creatures. Furthermore, Ev does not simulation multiple nearly-independent populations.Kleinman said:You almost got it right. This is a three trick pony. Ev shows that huge populations do not markedly accelerate evolution by random point mutations and natural selection.
This is absurd. How long did Gould say that punctuated equilibrium episodes last, what sort of biological mechanisms was he talking about, and how many generations of Ev simulation is equivalent to that time period?Ev shows that evolution by random point mutations and natural selection is far too slow for punctuated equilibrium as described by Stephen Gould to be mathematically possible.
This is so absurd it's not even worth analyzing.Ev shows that macroevolution by point mutations and natural selection is mathematically impossible.
That’s a simulation written by evolutionist Dr Tom Schneider, head of computational molecular biology at the National Cancer Institute and peer reviewed and published in the Oxford University Press journal Nucleic Acids Research. The java version of the program is available online and was written by Moderator Paul Anagnostopoulos. Paul is an excellent java programmer but we have got to work on his arithmetic.
Warning, this ride is not for evolutionists who are faint of heart.
For the fearless evolutionist, here is the URL: where you can access and run the program:
http://www.ccrnp.ncifcrf.gov/~toms/paper/ev/evj/evjava/index.html
Use this program at your own risk.
That’s not quite accurate, I have been able to run a 1000 base genome with a population of just over 1,000,000 using the pascal version of ev. In theory you can run larger cases but my computer only has 512 meg of memory and larger cases use a disk page file which slow the calculations a 1000 fold and would probably destroy my hard drive.Kleinman said:You almost got it right. This is a three trick pony. Ev shows that huge populations do not markedly accelerate evolution by random point mutations and natural selection.Paul said:With sufficient computing resources, you could run Ev with huge populations and determine how many generations are required. Neither you nor I have run Ev with any more than about 128,000 creatures. Furthermore, Ev does not simulation multiple nearly-independent populations.
I posted Gould’s estimates for punctuated equilibrium, earlier on this thread. He uses a range of values up to 20 million years but as low as 10-100,000 years. In one of Gould’s publications he even supposes a length of time of only 5-10,000 years. Read the quotes I posted from Dr Schneider’s references from his ev publication. If you consider your case of the evolution of 16 binding sites (96 loci) on a 100,000 base genome in 200,000,000 generations (over 500,000 years at one generation per day), you have already exceeded a large portion of the time span that Gould proposes and you still haven’t reached a realistic genome length. If you are talking about reptiles evolving into birds, not only will you have a genome much larger than 100,000 bases, you will have much longer generation times than 1 per day.Kleinman said:Ev shows that evolution by random point mutations and natural selection is far too slow for punctuated equilibrium as described by Stephen Gould to be mathematically possible.Paul said:This is absurd. How long did Gould say that punctuated equilibrium episodes last, what sort of biological mechanisms was he talking about, and how many generations of Ev simulation is equivalent to that time period?
That’s ok, I’ll post the data from ev that shows this.Kleinman said:Ev shows that macroevolution by point mutations and natural selection is mathematically impossible.Paul said:This is so absurd it's not even worth analyzing.
The first thing I did was discuss this directly with Dr Schneider and Paul Anagnostopoulos who is Dr Schneider’s java programmer for ev. Paul is the one who started this thread. I then asked Dr Schneider if he was willing to discuss this publicly because he had in the past but said no to my request, however Paul was willing to take up the banner. Dr Schneider had started a thread on the Evolutionisdead web site so I went ahead and started a discussion there. That went on for several months and there were a couple of evolutionists (including Paul) who were willing to debate this issue but they ran out of ideas on how to counter the data that was coming out of the model. Paul’s argument has gone from saying that ev simulates reality to it simulates a small portion of the rich evolutionary landscape. I also contacted the editors of Nucleic Acids Research who originally published Dr Schneider’s results based on unrealistic parameters in his model. I hoped to submit a letter to the editor. I told them that when realistic parameters are used in his model that it predicts that random point mutation and natural selection is too slow to account for macroevolution. They gave the usual evolutionist argument and said I was setting up a strawman, in addition they don’t take letters to the editor and to publish in their journal costs over $1000. So here we are James Randi educational forum.Level said:Thank you for the link. So if this proves, as you keep claiming, that large-scale evolution is impossible, what steps will you be taking in order to prove this to the scientific community? Are you going to organize a formal argument or is posting in a few online forums the extent of your evolution rebuttal?
What does any of this have to do with what I posted?First thing you have to be aware of is that the sickle-cell gene represents an example of microevolution which I believe occurs. The optimum is determined by the selective pressure. What people who believe in macroevolution have failed to explain is the de novo evolution of the hemoglobin gene. What kind of selective pressure could be sustained for a long enough period of time that would cause a series of microevolutionary steps to generate such a gene, especially when virtually all the preliminary steps would not yield a molecule that can selectively bind oxygen and carbon dioxide based on the partial pressures. Random mutations and natural selection do not explain the formation of such a gene and corresponding protein. Dr Schneider’s ev computer model shows how slow random point mutations and natural selection is.
I may be stupid, but I don't see how that addresses what I said at all.Recombination without error can never create a new gene. Recombination with natural selection can cause the loss of alleles.
I don't know, same reason you use a computer to balance your checkbook? Why not do a lot of stuff with paper and pencil?
Although you must realize a computer spreadsheet is not a simulation of a checkbook- it is in fact doing the same exact thing as a checkbook. Programs that model real world evolution, on the other hand, have many assumptions built in for simplification purposes.
Why would you shy away from doing experiments on real biology to prove your point? Wouldn't that be more effective than appealing to an intelligently designed assumption laden simulation?
Ooh, cool. Exactly which parameters did you use and how many generations did it take?Kleinman said:That’s not quite accurate, I have been able to run a 1000 base genome with a population of just over 1,000,000 using the pascal version of ev. In theory you can run larger cases but my computer only has 512 meg of memory and larger cases use a disk page file which slow the calculations a 1000 fold and would probably destroy my hard drive.
Exactly.So let me get this straight, Kleinman is saying evolution is bunk because it is incompatible with certain results of a simulation? That's rich.
That’s ok, Paul is Dr Schneider’s coworker and he is confoosed as well. Read my post #94 on this thread and I’ll walk you through the simulation.Gopi said:Pardon me if I'm a bit confused here, but... It seems to me that it is much easier to prove that something is possible with a simulation than to prove it is impossible.
If you stick with this discussion, this will make sense. You will get a little understanding of Information Theory which Dr Schneider used to write his computer simulation of evolution by random point mutations and natural selection. His simulation shows that it this mechanism can not account for macroevolution. Other evolutionists have tried to counter this finding by saying that recombination will speed up the macroevolutionary processes. Recombination can not create a new gene that is recombination can not add information to the gene pool.Kleinman said:Recombination without error can never create a new gene. Recombination with natural selection can cause the loss of alleles.Roboramma said:I may be stupid, but I don't see how that addresses what I said at all. It's quite possible that I just need things spelled out for me. It's happened before.
Cuddles said:Kleinman, I suggest you read ...
I couldn’t get you link to work. I do not believe in perpetual motion machines. Dr Schneider believes his simulation represents the real world.Cuddles said:I would be interested to know your views on AgingYoung, and if you believe a perpetual motion machine is possible. The argument is exactly the same as this one, that a simulation of one small part of the world is more accurate at representing the world than the world is itself.
I posted the results on the Evolutionisdead forum on the following page:Kleinman said:That’s not quite accurate, I have been able to run a 1000 base genome with a population of just over 1,000,000 using the pascal version of ev. In theory you can run larger cases but my computer only has 512 meg of memory and larger cases use a disk page file which slow the calculations a 1000 fold and would probably destroy my hard drive.Paul said:Ooh, cool. Exactly which parameters did you use and how many generations did it take?
There are four user modifiable controls below which allow the user to specify convergence conditions including when a Perfect creature has evolved which occurs when the random point mutations and natural selection process has located all gamma number of binding sites on any genome without erroneously identifying a binding site where one should not exist.
Yahzi said:An open question: Why isn't Kleinman simply settling for proving Schnieder wrong? "Look, your response to creationism fails. Try again." Instead, he wants to use a (possibly) failed argument by an evolutionist as a way to overturn all of evolution.
I believe prove my case that ev shows that macroevolution by point mutation and natural selection is mathematically impossible...