Kotatsu
Phthirapterist
The ev program only utilizes random base substitutions. Frame shifts, inversions, duplications and other forms of mutations as well as recombination are not used in the model
If so, all extrapolations as to the possibility of anything happening within a given timeframe made from the program where these mechanisms are not included to the real world where they are seem to be invalid.
It is like proclaiming that there are no possible prime numbers and then admitting that the program on which you base this claim only uses even numbers higher than 4.
It is like using a program on hydrogen bonding to disprove the existance of proteins, because hydrogen bonding, according to the program, is insufficient to account for the flexibility and integrity of something as complex and as large as a protein, ignoring that other known types of bonding may be relevant for the structure and function of a protein, rendering the computer program, not necessarily flawed, but too limited in scope as to the selection of applicable and available types of bondings, to be of any use other than as an exclusively mental exercise for people with small budgets who cannot afford more sophisticated programs (if such exist).
In each of these cases, it is the limitations of the program and its user that results in the strange conclusions. I believe the conclusion is simply reversed. It shouldn't be "Proteins cannot exist because hydrogen bonding is insufficient to maintain them", but rather "If hydrogen bonding was the only kind of chemical bond, proteins would not be able to be maintained". Similarly, not "Genes cannot have evolved to where they are today because point mutations are too slow", but rather "If using only point mutations, there is too little time in which to evolve the genes we see today".
Luckily, this sort of misapprehension can be corrected by a greater understanding and fuller inclusion of --- at least --- all known mechanism which influence the phenomenon.