Merged 2019-nCoV / Corona virus

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alfaniner said:
When the White House Chief of Staff suggests one solution to the concern about Covid-19 and the market is to turn off your TV for 24 hours, there is nothing so stupid that can be said that can't be assumed to be a person's belief.
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Yeah. At least King Canute knew he couldn’t stop the tide ... it seems Mulvaney believes he (and his boss) can ...
 
When I was in the US Army as a Redleg (artilleryman) if we had not had proper NBC suits and equipment for a drill or a deployment, heads would have rolled.
 
Skeptic Ginger said:
That is relapse, not reinfection, though your link has a good discussion of all sorts of hypothetical explanations, none of which there is actual evidence of given we don't have any widely used antibody tests yet. From your link:
Despite this also from your link, there's nothing to base this on given the available tests.
And this is true with dengue virus but there's no evidence people are getting a more serious second bout of disease:



It has implications though that persons deemed well might still be shedding virus and be contagious.

I looked into this:

I found one report (still from a news report) that a Dr Li QinGyuan was seeing the return of positive tests in people previously cleared. There was no mention of relapsing disease.

https://www.usatoday.com/story/news...00-deaths-can-you-get-virus-again/4804905002/


In another report which I cannot read all of:
https://www.caixinglobal.com/2020-0...uangdong-tested-positive-again-101520415.html
This version in Chinese that can be translated is an accessible version.
http://china.caixin.com/2020-02-28/101521885.html

Antibody production isn't likely to be being tested given how new that testing is:
https://www.sciencemag.org/news/202...se-antibody-test-track-coronavirus-infections
Singapore claims first use of antibody test to track coronavirus infections

https://www.cdc.gov/coronavirus/2019-ncov/about/testing.html


Initial work to develop a serology test for SARS-CoV-2 is underway at CDC.

What it appears is that they are using the PCR antigen testing that looks for the virus, not the antibodies. Those tests are using multiple serum samples from blood to saliva to feces. Without knowing how they determined the virus was clear and how it was found again we don't really know what is going on here.

Lancet has recently reported on research on serial testing of viral loads to track what happens with infected people.
https://www.thelancet.com/journals/...0)30113-4/fulltext?dgcid=raven_jbs_etoc_email
Sample sizes are small. Virus was found as much as 15 days after it was first detected. If you look at the graph for patient #2 their viral load went up and down before it cleared.

I don't think any of this suggests failed immune response, rather it looks more like people continue to test positive for virus after recovery. This is not unusual. For some viral pathogens it's common that they remain contagious after the symptoms resolve.

It's going to take more time before this is sorted out.
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I think you are confused about your terminology, or don't understand what you are posting about. PCR looks for DNA, or if you utilise a reverse transcriptase (rtPCR) you can look for RNA which is relevant for covid 19 which is caused by an RNA virus. Antigen testing is done using a monoclonal antibody technique such as an ELISA. This would be looking for viral proteins e.g. in respiratory secretions. I think what you are referring to is an assay for antibodies against SARS CoV 2 which would be done by using artificially produced viral antigens (proteins) in some type of sandwich ELISA to measure levels of antibodies in survivors of covid 19.
 
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Looking at the case numbers, I reckon Italy has at least 1000 more to come, South Korea looks to have stabilised the increase, and Iran is at least 3000 light.

Someone should be asking how Singapore went from sudden outbreak to no cases in a fortnight. We should start copying whatever they're doing. No deaths there, either.
 
The Atheist said:
Someone should be asking how Singapore went from sudden outbreak to no cases in a fortnight. We should start copying whatever they're doing. No deaths there, either.
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It probably just disappeared, miraculously ...
 
Washington Post has breaking news that there is now a second case of unknown origin in California. They say this suggests that it is on the loose in the wild.
 
Second case is in Santa Clara County..the heart of Silicon Valley.
Bad news. The first was in a small town in the central valley;this one if in a major population center.
 
JeanTate said:
Ahem ... that’s the FSM ... I’m not a big fan of FGM (but perhaps Pence is?).
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My error. When I say it, as I'm sometimes wont, I turn it into a kid's speak. Just wrote it that way w/o thinking.

"Flying ...Ghetty Monster"
 
Planigale said:

I think you are confused about your terminology, or don't understand what you are posting about. PCR looks for DNA, or if you utilise a reverse transcriptase (rtPCR) you can look for RNA which is relevant for covid 19 which is caused by an RNA virus. Antigen testing is done using a monoclonal antibody technique such as an ELISA. This would be looking for viral proteins e.g. in respiratory secretions. I think what you are referring to is an assay for antibodies against SARS CoV 2 which would be done by using artificially produced viral antigens (proteins) in some type of sandwich ELISA to measure levels of antibodies in survivors of covid 19.
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[snipped my actual reaction to this so the posts don't end up in AAH. You can guess what it was from this BS:]
you are confused about your terminology, or don't understand what you are posting about
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ELISA is a screening test. Do you have evidence that is what China is using?

And if you think they did an antibody assay, prove the test is even available. In the US only the test being used is PCR. And I don't think many people care if one prefaces PCR with rt in this forum.

Real-Time RT-PCR Resources
Processing of Sputum Specimens for Nucleic Acid Extraction
 
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The latest patient diagnosed with the coronavirus in England is the first to catch it in the UK.

It is unclear whether this was directly or indirectly from someone who recently returned from abroad, England's chief medical officer said.

The man is a resident of Surrey who had not been abroad recently himself.
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https://www.bbc.co.uk/news/uk-51683428
 
dann said:
We have case #2 in Denmark. Another Dane who's been to Italy. He's been running around with symptoms of Covid-19 for nine days before calling his MD.
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That's one.

William Parcher said:
Washington Post has breaking news that there is now a second case of unknown origin in California. They say this suggests that it is on the loose in the wild.
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Two.

Captain_Swoop said:
The latest patient diagnosed with the coronavirus in England is the first to catch it in the UK.
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Three.

This is going to get very, very ugly.
 
William Parcher said:
Paper towels can be used as toilet paper. You can cut or tear it so that it's almost identical.
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You don’t want to flush material down the toilet that isn’t meant to be flushed or you could block up the drains.

Besides, tissues and other kinds of paper towels are also disappearing off the shelves. Presumably people have a lot of colds, flus, hay fever etc...
 
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