Mach you are knowledgeable on many things, and your input here is helpful. But biology is not your forte, you really should not state as facts things that are not true. Bone and cartilage are connective tissue, cartilage in particular is almost cell free and will contain very little DNA. Bone cartilage and muscle would have been seen when the knife was examined, in fact did not Stefanoni in fact observe cellular material? Cellular material that turned out to be starch granules? The presence of which indicates that the knife had not been thoroughly cleaned? So the knife was examined for the type of material you refer to and it was absent. The catalytic tests for haemoglobin are very sensitive and can detect only a few molecules. to get a DNA profile you need intact many DNA molecules.
Haemoglobin is a 'tough' molecule it is resistant to cleaning and will get in to crevasses. DNA is relatively soluble, and degrades easily so no profile is extractable. The quantity of haemoglobin is massively greater than DNA in blood. If this knife were the murder weapon it cut a major vessel, causing massive bleeding, it would have been covered in blood. The ratio of haemoglobin to blood is orders of magnitude different than any differences in sensitivity testing, 30,000,000,000 : 1. Check the literature. Read the references given above.
As a simple sense check, take the luminol positive traces that you ascribe to being blood. They gave a strong presumptive test for blood, but they were negative for DNA.
As an aside I also would argue that the relative ratios of Knox and Kercher DNA also prove that Knox DNA could not have arisen at the time of the crime if the knife was used in the crime. To be put simply any knife used in the way proposed would contain far more DNA of the victim than the wielder, any cleaning would clean the DNA of victim and wielder equally. The ratios would remain the same. That there was a significant amount of Knox DNA on the handle is agreed. Using this observation to argue that Knox was the wielder of the knife is just wrong.
Exactly this - trying to wash blood of anything is incredibly difficult
And to quote C&V again
3. Taking into account that none of the recommendations of the international scientific community relative to the treatment of Low Copy Number (LCN) samples were followed, we do not accept the conclusions regarding the certain attribution of the profile found on trace B (blade of knife) to the victim Meredith Susanna Cara Kercher, since the genetic profile, as obtained, appears unreliable insofar as it is not supported by scientifically validated analysis;
And for this arguing for guilt, please explain why:
1) No evidence they were in the room where the murder took place - all the evidence, fingerprints, footprints and DNA was of Rudy Guede, Rudy Guede's DNA was also found inside of Meredith Kercher
2) No blood was found on the clothes Amanda had been seen wearing only a few hours earlier
3) The autopsy report indicates a likely time of death too early for Amanda and Raffaele to be involved, as there is computer evidence at Raffaele's flat
4) Suggesting that the burglary was staged is ludicrous - Rudy Guede was a known burglar who had a history of breaking into buildings by throwing rocks through second story windows. This is EXACTLY what happened at the cottage that night
5) The knife suggested as the murder weapon did not match the wounds and did not match the print of the knife at the scene
6) Independent experts who looked at the knife, did NOT find DNA of Meredith Kercher and widely discredited the prosecution's findings
7) the bra clasp found at the scene six weeks later was also discredited by independent experts
8) The pathologist who performed the autopsy believed there was no evidence from the wounds to conclude that there were multiple attackers
9) Meredith Kercher was killed and sexually assaulted by Rudy Guede, when she came home early and interrupted a burglary. This is far more believable than the multiple scenarios suggested by the prosecution, which now include a satanic ritual, a Fifty Shades of Grey style sex game and most recently am argument over Guede doing a poo