That made absolutely no sense.
I suspect you were able to figure this out by now, but just in case, I'll simplify it even further:
You observe that a substance has promise for the prevention or treatment of a dangerous disease. You clearly would like to help people who have the disease, but you also want to be certain the substance really works and is safe. So you test it, right? How does this testing scheme seem to you?
Test the substance in cells grown in a petri plate. If it looks like it works and doesn't hurt the cells:
Test the substance in a variety of different animals. If it looks like it works and doesn't hurt the animals:
Test the substance in a small number of human volunteers. If it looks like it works (recognizing the statistics of small samples are tricky) and if it doesn't hurt the volunteers:
Test the substance in a larger number of human volunteers. Study how the substance is metabolized, what it is converted into, how long it stays in the body, and how it is excreted. If it looks like it works and doesn't hurt this group:
Test the substance in a still larger group of volunteers. If it works and doesn't hurt this group:
Allow it to be used by doctors to treat the disease. But continue to monitor it and require any adverse effects to be reported. If there are problems, limit or ban further use of the drug.
Clayton, the question I asked you was: if this testing strategy was put into place, would it overcome your concern that a given "substance," when put in the body, might be dangerous? Remember, the substance has the promise to help treat a disease that itself is dangerous: you can't just say it is safer to do nothing...