I don't think many worlds is the simplest interpretation, and would argue that Copenhagen is.
As far as the mathematical formalism goes, they both require something of a collapse postulate. Unless some major breakthrough I have no awareness of has been made, the Born probabilities have not been deduced from the postulates of quantum mechanics sans collapse, and thus need to be put into the theory as a postulate. Many worlds and Copenhagen have a different interpretation of what the probabilities mean---Copenhagen just says they're the probabilities of getting some outcomes, while many worlds states that they're proportions of numbers of worlds---but both need them.
Both interpretations assume the existence of subjects, or observers. Copenhagen has the observer as what makes physical observables determinate. Many worlds has the observer as something that can only experience certain kinds of states, and so finds itself in one of many split worlds (rather than in one of the superposition states that cannot be experienced).
What many worlds does that Copenhagen doesn't is assume the existence of an unobservable entity---is asserts that the wave-function is a physical entity. In Copenhagen, the wave-function is just a mathematical tool for evaluating probabilities, which we are forced to use because particles don't have a determinate location in space. The mathematical formalism is actually quite natural: we can represent integrable probability distributions by square-integrable complex functions which return the distribution when multiplied by their conjugate. The position operator, its infinitesimal translation generator, and the infinitesimal time translation generator (assuming it doesn't explicitly depend on time, anyway---I'm not sure about the general case, I always have trouble with time-dependent Hamiltonians) obey Hamilton's equations right off the bat, and if the distribution has all finite moments it obeys the central limit theorem. In the limit of very small standard deviations (compared to the mean values of the observables themselves) it's fair to say that the observables "are" the mean values, giving a correspondence with the classical position, momentum, and Hamiltonian.
All of the postulates of quantum mechanics make sense in this interpretation. Born probabilities involve taking the square of the wave-function because the wave-function is defined that way. "Collapse" isn't an actual, objective physical process (unlike in von Neumann's interpretation). In contrast, if the wave-function is a "real" physical entity, it isn't at all obvious that taking its square should produce a probability, nor that the 'mean value' of some observable O should take the form <\Psi|O|\Psi>. In addition to this, since many-worlds seems to suppose that the wave-function is fundamental, it's curious that there should be certain states of subjective experience which can be experienced (and thus constitute worlds) and which cannot be (and thus don't constitute individual worlds---the world had to split). In Copenhagen, experience is at least taken as given.