It has already met common epidemiological definition of Pandemic.
I almost think WHO is waiting to make it level 6 because going directly from 4 to 6 would have made it look like either their level designations were not useful or they were late in upping the risk from 4. They are pretending there is actually a 5th step in there.
Think about the following time line and the evidence for how many cases are not in the official count. When this is over there is going to be an incredible amount of epidemiological data to analyze. The public is so expecting instant doom or there must be no threat. They seem to have little clue about the implications of how fast this strain has spread or about what such a pandemic should look like through observation tools never before seen in history.
I've posted links to this data or other people have in past posts so I'm not going to put cites for all the facts here.
The first inkling of this new strain entering the population occurred in early March when a town in Mexico, La Gloria, experienced widespread serious upper respiratory infections and 3 kids died. A small number of samples were recovered after the number of cases subsided and were positive for the new flu strain.
A woman with a job going door to door in the vicinity of La Gloria developed pneumonia with the onset of illness around the first week in April. She eventually died in Mexico City on April 13th.
An amplifying event occurred with a Mexican holiday, Semana Santa, the week of April 5th to the 12th when many people in Mexico travel in Mexico.
A second amplifying event probably took place during Spring breaks for US colleges when lots of students travel to Mexico and return to mix with large clusters of fellow students. This year's breaks began the week of February 16-20. The largest number of colleges were off March 16-20, the second biggest group, March 9-13 and the last break was April 6-10, 2009. Perhaps only the last week or two of travelers were affected.
There is continual travel between Mexico and the US because we have such a large overlapping population.
Swine-Origin Influenza A (H1N1) Virus Infections in a School --- New York City, April 2009
On April 24, 2009, CDC reported eight confirmed cases of swine-origin influenza A (H1N1) virus (S-OIV) infection in Texas and California (1)
On April 23, DOHMH was notified of approximately 100 cases of mild (uncomplicated) respiratory illness among students at an NYC school (high school A) with 2,686 students and 228 staff members. During April 23--24, a total of 222 students visited the school nursing office and left school because of illness. Given initial reports on April 24 of what was later determined to be a large S-OIV outbreak in Mexico, DOHMH decided to rapidly mobilize staff members to go to high school A to collect nasopharyngeal swabs from any symptomatic students. On April 24 (a Friday), DOHMH staff members collected nasopharyngeal swabs from five newly symptomatic students identified by the school nurse and four newly symptomatic students identified at a nearby physician's office.
Four patients reported travel outside NYC within the United States in the week before symptom onset, and an additional patient traveled to Aruba in the 7 days before symptom onset. None of the 44 patients [interviewed by phone] reported recent travel to California, Texas, or Mexico.
Illness onset dates ranged from April 20 to April 24; 10 (23%) of the patients had illness onset on April 22, and 28 (64%) had illness onset on April 23 (Figure). The most frequently reported symptoms were cough (in 43 patients [98%]), subjective fever (42 [96%]), fatigue (39 [89%]), headache (36 [82%]), sore throat (36 [82%]), runny nose (36 [82%]), chills (35 [80%]), and muscle aches (35 [80%]). Nausea (24 [55%]), stomach ache (22 [50%]), diarrhea (21 [48%]), shortness of breath (21 [48%]), and joint pain (20 [46%]) were less frequently reported but still common. Among 35 patients who reported a maximum temperature, the mean was 102.2°F (39.0°C) (range: 99.0--104.0°F [37.2--40.0°C]). In total, 42 (95%) patients reported subjective fever plus cough and/or sore throat, meeting the CDC definition for influenza-like illness (ILI) (2). At the time of interview on April 27, 37 patients (84%) reported that their symptoms were stable or improving, three (7%) reported worsening symptoms (two of whom later reported improvement), and four (9%) reported complete resolution of symptoms. Only one reported having been hospitalized for syncope and released after overnight observation.
Per WHO's last update,
"30 April 2009 -- The situation continues to evolve rapidly. As of 17:00 GMT, 30 April 2009, 11 countries have officially reported 257 cases of influenza A (H1N1) infection."
Now there are a couple important things to point out here. One is the short time span. In 2 months or maybe 2.5 or so this infection went from the first patient to world wide early phase pandemic. That's really really fast.
Compare that to SARS which festered in Guangdong China for 4 months (Nov, 2002 to Feb, 2003), broke out into Hong Kong in March and spread from Hong Kong to 18 countries in April but only Canada and the US had clusters of cases outside SE Asia. The other countries merely had citizens who were infected elsewhere and became ill after arriving home.
In addition, with SARS, most cases could be connected.
The second important thing to consider is how many people are really infected here. The NY school came to the attention of health authorities because so many kids were ill at the same time, (
"222 students visited the school nursing office and left school because of illness"). Only 7 were tested, (
"DOHMH staff members collected nasopharyngeal swabs from five newly symptomatic students identified by the school nurse and four newly symptomatic students identified at a nearby physician's office") That doesn't mean only 44 of the 222 kids had swine flu. By case definition, most if not all of them met the definition of a probable case.
And these were not kids who went as a group to Mexico. So on April 20th there were 10 sick kids and by 3 days later the total had reached 222 out of a population of 3,000.
To anyone who looks carefully at this evidence and understands the epidemiology we are seeing here, this organism is incredibly contagious. The absence of known exposure sources in many cases suggests many undetected infections. The speed of spread is unusual even for influenza.
We still don't have much of a clue how many serious illnesses we are going to see. It could be that because we have never tracked seasonal flu in this much detail, that there are many more mild cases of influenza during flu season than are typically recognized. To conclude nothing is going to come of this in the way of serious illness is naive.
At a minimum staffing shortages and closed businesses are going to affect lots of people. I wrote a sick leave policy yesterday and I started adding it up and the hospital I was writing it for is going to have some serious issues. If you are exposed to sick family members, you have to stay home. If the schools close some workers will have child care issues. If workers are ill, they can't return for 7 days even if they feel better. This is going to be a mess even if only a few serious cases occur.
There is already a local shortage of both Relenza and Tamiflu if you want to buy some to dispense from your office practice. I'm not sure how the supply is for filling individual prescriptions. Public health is triaging prophylaxis and treatment. If you are seriously ill or have a high risk condition, you get treated. If it's mild or you've been exposed but you don't have specific risks, no prophy for you. I think health care workers can get prophylaxis, but not if there is none to be had. The Feds are being quite stingy. I say they didn't stockpile enough. Hopefully this pandemic will be a nice dry run to see what problems we might encounter when a more lethal phase or strain comes around.