gumboot
lorcutus.tolere
- Joined
- Jun 18, 2006
- Messages
- 25,327
Skeptigirl I just want to reiterate that my remarks are specifically in regards to the likelihood of a catastrophic Influenza pandemic. I am not debating the likelihood of an especially deadly strain of Influenza, nor the likelihood of an influenza epidemic.
I have no dispute with the information you have provided (Which incidentally I have read). I am not trying to propose an alternative hypothesis for the evolution of the Spanish Flu.
The bottom line is, in order for any infectious disease pandemic to be catastrophic, a lot of people have to be infected. If you set a figure that 2% of world population would be a catastrophic event, as an absolute minimum 2% of the world's population have to be infected. As the mortality rate of the infectious disease decreases, the percentage of people that need to be infected to reach that 2% also increases.
The only two documented catastrophic pandemics in human history that I am aware of are the Black Death of the mid 14th Century and the Spanish Flu of 1918/1919. I would classify the Black Death as significantly more catastrophic than the Spanish Flu.
My issue, therefore, with the H5N1 virus (or any other future infectious disease) is not that it could be deadly, and not that it could be a pandemic. My issue is with the idea that it will be catastrophic. Not to see there won't be future catastrophic pandemics. There could very well be. But I think it is exceedingly unlikely. I think figures such as billions dead - which some people have claimed are a possible outcome from an H5N1 pandemic - are even less likely.
My reasoning for this is that both the Black Death and the Spanish Flu did not appear in isolation. Certain event-specific conditions pushed the pandemic into the catastrophic category.
Half of the equation is the disease itself. How infectious is it, and how deadly? A highly infectious and very deadly disease is more likely to produce a catastrophic pandemic than a disease that is hard to transmit and has a low mortality rate. H5N1, for example, certainly appears to have the potential to be both deadly and highly infectious.
This aspect deals with spread of the virus between individual humans. Is it spread through body fluid? Blood only? Coughing? Physical contact, etc. This aspect comes into play once a disease enters one member of a specific social group. How quickly will it spread to other members of the same social group. This has to do with the biology of the virus itself, but also the biology of the members of the social group.
For the purposes of this, a social group is considered a group of people with frequent direct contact - people you live with, friends, work colleagues, family, etc.
But the other half of the equation is how rapidly the virus is spread amongst different social groups. This aspect it not a matter of the biology of the virus itself. It is a product of human behaviour and social dynamics.
I maintain, in the example of the Black Death, specific factors (mass starvation and malnourishment) within the biology of the social groups contributed significantly to the catastrophic progression of the pandemic. Once a member of the social group became infected, the weak and sick members of the social group would quickly succumb.
In the example of the Spanish Flu, unique factors (starvation, sickness, stress, tiredness, malnourishment, injury, poor medical treatment, etc) within the biology of one particular social group (WWI soldiers) contributed significantly to the progression of the disease within that social group.
In the modern day, I do not believe specific factors of this nature are likely to be present in all social groups. Most of the western world is relatively healthy, hygienic (except my flatmates
), and has access to reasonable medical care.
However, in the modern world, specific social groups are more vulnerable. For example refugees, people suffering from famine, people living in areas with poor medical care and sanitation, and so forth.
In the example of the Black Plague, unique aspects of the social groups and their interaction also contributed to the catastrophic progression of the pandemic. Medieval European communities were dense networks of villages, and the members of these communities had constant close interaction with other members of the community. The Great Famine resulted in displacement of large populations, and an increase in criminal activities and overall population movement.
In the example of the Spanish Flu, again the soldiers of WWI are a key social group. They were a highly concentrated social group, allowing for high rates of transmission between members. But a normal social group is relatively stable. In contrast, this particular social group completely dispersed and ceased to exist at the end of WWI. The members returned to their former social groups, allowing for high rates of transmission between social groups.
What was significant about this was how significant a percentage of the population it was.
In contrast, there is the modern age.
A large percentage of the modern population move between social groups. However, unlike in the example of WWI soldiers, these travellers do not originate from a single social group. Thus infection of a single large social group is less capable of quickly spreading to infect multiple social groups. In In addition, people are less likely to travel when sick, thus an infected person is less likely to travel. In addition, those social groups which are more vulnerable to infection are also less likely to travel. In the example of the Spanish Flu, the especially vulnerable and highly infected group - WWI soldiers - were the most likely to travel.
Social dynamics of today are very different to Medieval Europe. Social group interaction is significantly decreased. For example, in Medieval times a typical peasant would closely interact with 400 - 1000 people on a daily basis. In contrast, most modern citizens of western nations only interact on a daily basis with a very small group of people (very close friends, people we live with, and people we work with).
Essentially, while there is greater interaction between social groups, there are many more social groups, and they are much smaller. This limits the disease's ability to spread.
A final key factor is advancements in medical science, understanding of pandemics, and infectious diseases, and a generally better understanding of hygiene.
As we saw with the SARS virus, humans are capable of significantly restricting the spread of a virus. When an outbreak occurs, they are capable of quickly limited the spread. This happens both an an inter-group level and an intra-group level. For example governments can limit air travel, or establish quarantines, and individuals can restrict their own movements, to reduce spread between social groups. And individuals on a daily basis restrict the spread of illness between members of the same social group (not going to work when you're sick, not visiting friends, etc).
The specific study of pandemics and particular infectious diseases continually offers up a wealth of new information which will aide in the prevention of future pandemics.
For the reasons outlined above, I argue that a catastrophic epidemic in the modern world is exceedingly unlikely.
-Gumboot
I have no dispute with the information you have provided (Which incidentally I have read). I am not trying to propose an alternative hypothesis for the evolution of the Spanish Flu.
The bottom line is, in order for any infectious disease pandemic to be catastrophic, a lot of people have to be infected. If you set a figure that 2% of world population would be a catastrophic event, as an absolute minimum 2% of the world's population have to be infected. As the mortality rate of the infectious disease decreases, the percentage of people that need to be infected to reach that 2% also increases.
The only two documented catastrophic pandemics in human history that I am aware of are the Black Death of the mid 14th Century and the Spanish Flu of 1918/1919. I would classify the Black Death as significantly more catastrophic than the Spanish Flu.
My issue, therefore, with the H5N1 virus (or any other future infectious disease) is not that it could be deadly, and not that it could be a pandemic. My issue is with the idea that it will be catastrophic. Not to see there won't be future catastrophic pandemics. There could very well be. But I think it is exceedingly unlikely. I think figures such as billions dead - which some people have claimed are a possible outcome from an H5N1 pandemic - are even less likely.
My reasoning for this is that both the Black Death and the Spanish Flu did not appear in isolation. Certain event-specific conditions pushed the pandemic into the catastrophic category.
Half of the equation is the disease itself. How infectious is it, and how deadly? A highly infectious and very deadly disease is more likely to produce a catastrophic pandemic than a disease that is hard to transmit and has a low mortality rate. H5N1, for example, certainly appears to have the potential to be both deadly and highly infectious.
This aspect deals with spread of the virus between individual humans. Is it spread through body fluid? Blood only? Coughing? Physical contact, etc. This aspect comes into play once a disease enters one member of a specific social group. How quickly will it spread to other members of the same social group. This has to do with the biology of the virus itself, but also the biology of the members of the social group.
For the purposes of this, a social group is considered a group of people with frequent direct contact - people you live with, friends, work colleagues, family, etc.
But the other half of the equation is how rapidly the virus is spread amongst different social groups. This aspect it not a matter of the biology of the virus itself. It is a product of human behaviour and social dynamics.
I maintain, in the example of the Black Death, specific factors (mass starvation and malnourishment) within the biology of the social groups contributed significantly to the catastrophic progression of the pandemic. Once a member of the social group became infected, the weak and sick members of the social group would quickly succumb.
In the example of the Spanish Flu, unique factors (starvation, sickness, stress, tiredness, malnourishment, injury, poor medical treatment, etc) within the biology of one particular social group (WWI soldiers) contributed significantly to the progression of the disease within that social group.
In the modern day, I do not believe specific factors of this nature are likely to be present in all social groups. Most of the western world is relatively healthy, hygienic (except my flatmates
However, in the modern world, specific social groups are more vulnerable. For example refugees, people suffering from famine, people living in areas with poor medical care and sanitation, and so forth.
In the example of the Black Plague, unique aspects of the social groups and their interaction also contributed to the catastrophic progression of the pandemic. Medieval European communities were dense networks of villages, and the members of these communities had constant close interaction with other members of the community. The Great Famine resulted in displacement of large populations, and an increase in criminal activities and overall population movement.
In the example of the Spanish Flu, again the soldiers of WWI are a key social group. They were a highly concentrated social group, allowing for high rates of transmission between members. But a normal social group is relatively stable. In contrast, this particular social group completely dispersed and ceased to exist at the end of WWI. The members returned to their former social groups, allowing for high rates of transmission between social groups.
What was significant about this was how significant a percentage of the population it was.
In contrast, there is the modern age.
A large percentage of the modern population move between social groups. However, unlike in the example of WWI soldiers, these travellers do not originate from a single social group. Thus infection of a single large social group is less capable of quickly spreading to infect multiple social groups. In In addition, people are less likely to travel when sick, thus an infected person is less likely to travel. In addition, those social groups which are more vulnerable to infection are also less likely to travel. In the example of the Spanish Flu, the especially vulnerable and highly infected group - WWI soldiers - were the most likely to travel.
Social dynamics of today are very different to Medieval Europe. Social group interaction is significantly decreased. For example, in Medieval times a typical peasant would closely interact with 400 - 1000 people on a daily basis. In contrast, most modern citizens of western nations only interact on a daily basis with a very small group of people (very close friends, people we live with, and people we work with).
Essentially, while there is greater interaction between social groups, there are many more social groups, and they are much smaller. This limits the disease's ability to spread.
A final key factor is advancements in medical science, understanding of pandemics, and infectious diseases, and a generally better understanding of hygiene.
As we saw with the SARS virus, humans are capable of significantly restricting the spread of a virus. When an outbreak occurs, they are capable of quickly limited the spread. This happens both an an inter-group level and an intra-group level. For example governments can limit air travel, or establish quarantines, and individuals can restrict their own movements, to reduce spread between social groups. And individuals on a daily basis restrict the spread of illness between members of the same social group (not going to work when you're sick, not visiting friends, etc).
The specific study of pandemics and particular infectious diseases continually offers up a wealth of new information which will aide in the prevention of future pandemics.
For the reasons outlined above, I argue that a catastrophic epidemic in the modern world is exceedingly unlikely.
-Gumboot