I think that unless someone can get the Military and Police on board, it'd be a very short revolution.
Consider all of the modern State vs Militia where it has come down to a shooting match, who won?
And you have to remember that in all those cases, the State was generally trying to minimise casualties, what do you think it would be like it they decided that casualties didn't matter?
Another issue is that States these days are far more integrated between Republican and Democrats. Yes many have more of one than the other, but unlike in 1861, there is no contiguous set of States who have an overwhelming population that are supporting one side or the other. This means that any violence would not involve States, but rather would end up being more neighbour vs neighbour, and as such there would be a broader ability for the Federal State to declare emergency powers and and then treat those fighting their supporters as Terrorists.
Armed action against the US Government is really not an option these days, and against a Tyrannical Government that is willing to do anything it wants, it would be little more than suicide.