Ok, let's quote an other study:
"Drs. Carhart-Harris, Nutt, and colleagues used functional magnetic resonance imaging (fMRI) to study the effects of psilocybin on brain activity in 30 experienced hallucinogen users. In this study, intravenous administration of 2 mg of psilocybin induced a moderately intense psychedelic state that was associated with reductions of neuronal activity in brain regions such as the medial prefrontal cortex (mPFC) and the anterior cingulate cortex (ACC).
The mPFC and ACC are highly interconnected with other brain regions and are believed to be involved in functions such as emotional regulation, cognitive processing, and introspection. Based on their findings, the authors of the study concluded that hallucinogens reduce activity in specific “hub” regions of the brain, potentially diminishing their ability to coordinate activity in downstream brain regions. In effect, psilocybin appears to inhibit brain regions that are responsible for constraining consciousness within the narrow boundaries of the normal waking state, an interpretation that is remarkably similar to what Huxley proposed over half a century ago."
https://www.scientificamerican.com/article/do-psychedelics-expand-mind-reducing-brain-activity/