The Man
Unbanned zombie poster
As I understand it, the brain undertakes considerable unconscious processing of ongoing data, already establishing meaning at this level, and then decides which streams should amplified and propagated across multiple brain modules (consciousness).
While there certainly is a considerable amount of unconscious processing that takes place and it would seem unlikely that at least some extent of meaning doesn’t get established there, we can still consciously interrogate, discern and assign meaning. Even to the point of considering and applying the meanings ascribed by others. However, regardless of where meaning may or may not be assigned and what might or might not get amplified and propagated, that active suppression is a specific function of certain neurons and neurotransmitters should be a fundamental part of any understanding of brain function, if it isn’t already.
But I don't follow how the presence of a brain chemical like GABA could really be central to the creation of consciousness. Isn't it more likely that how neurons are interconnected is more in the central role? If the pattern of interconnection facilitates the generation of more information then wouldn't this be more the nub of it?
This is specifically about how neurons interconnect via neurotransmitters. GABA isn’t just present, like any neurotransmitter it is specifically released and then reabsorbed (reuptake) before it can be released again. Of course reuptake can never be absolute so some amount of neurotransmitters remain present in the synaptic gap. As GABAergic neurons (neurons that release GABA) are different they have their own interconnections (axon terminals) to other neurons. I have seen some indications that GABA receptors are more concentrated along the postsynaptic dendrite stem with the typical excitatory neurotransmitter receptors being more concentrated at the dendrite tip. However I’ve yet to review sufficient current literature to confirm that configuration. None the less, still different action and different presynaptic neurons so different interconnections. If I recall correctly something like 30 to 40% of all synapses involve GABA and they are located in all regions of the brain.
GABAergic-synapse
https://en.wikipedia.org/wiki/Gamma-Aminobutyric_acid#/media/File:GABAergic-synapse.gif
Some other helpful links
https://en.wikipedia.org/wiki/Neurotransmitter
https://en.wikipedia.org/wiki/Reuptake
http://www.mrcbndu.ox.ac.uk/publica...ed-basket-and-dendrite-targeting-interneurons
https://en.wikipedia.org/wiki/Neuron
https://en.wikipedia.org/wiki/GABA_reuptake_inhibitor
The last link refers to GABA reuptake inhibitors,. Chemicals that prevent or slowdown the reuptake of GABA. The “indications” portion gives an idea of the result of too little GABA floating around while the “effects” portion give an ideas of the results of perhaps too much GABA.. From them and the overdose portion the potential influence of GABA on consciousness should be obvious.