They only have a few observations yet to predict the orbit - and these have uncertanties of measurement.
So you run the calculation lots of times, using all the most extreme possible values for the observations. For example, if you measure a speed as 60 +/- 2, you run the calcs for 58 and 62.
The uncertain orbit of the NEO (Near Earth object) puts it somewhere in a cone from its present position - sort of like a shotgun spread pattern. At some point in the future, you can predict a certain sized sphere (or elipsoid) of space that the object will be in - the further into the future, the bigger that sphere gets.
So you work out how big the sphere is at the time when it comes close to the Earth, and divide the cross sectional area of the place it might be in by the cross sectional area of the Earth, using suitable probabilty weightings (the object is more likely to be near the centre of the cone than the edges). The ratio of the areas, weighting adjusted, gives the chances of a hit.
As they take more measurements over the next few weeks, the uncertainty will grow less. Pretty soon, they will be able to say it is definitely going to miss (we hope).