Johnny Pneumatic
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I've been so busy lately and my genetics paper for Biology has slipped up on me. My topic is Sickle Cell Anemia. I need informational sources on it, please help!
Sickle Cell Genetics Paper
- Thread starter Johnny Pneumatic
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geni
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SkepticJ said:I've been so busy lately and my genetics paper for Biology has slipped up on me. My topic is Sickle Cell Anemia. I need informational sources on it, please help!
well this should give you an idea what to look for
http://en.wikipedia.org/wiki/Sickle_Cell_Anemia
Paul C. Anagnostopoulos
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Don't forget to discuss the relation between sickle cell and malaria.
~~ Paul
~~ Paul
http://www.innvista.com/health/ailments/anemias/sickhist.htm
Paul is right. Anthony Allison had , I believe, lived in East Africa. He suspected that the distribution of SCA was related to malaria.
It appears that the mutation responsible for SCA confers resistance to malaria and so could spread through west Africa although itself a harmful mutation. Among descendants of west African slaves in the US, the condition has no positive benefit , while retaining it's negative effects.
Check out Thalassaemia too- another form of amaemia, widespread around the eastern Mediterranean. It seems to confer similar resistance to malaria.
It seems probable that many other human genes have evolved in response to selective pressure from malaria and other endemic disease. The SCA mutation is just a good example .
Paul is right. Anthony Allison had , I believe, lived in East Africa. He suspected that the distribution of SCA was related to malaria.
It appears that the mutation responsible for SCA confers resistance to malaria and so could spread through west Africa although itself a harmful mutation. Among descendants of west African slaves in the US, the condition has no positive benefit , while retaining it's negative effects.
Check out Thalassaemia too- another form of amaemia, widespread around the eastern Mediterranean. It seems to confer similar resistance to malaria.
It seems probable that many other human genes have evolved in response to selective pressure from malaria and other endemic disease. The SCA mutation is just a good example .