Jon-Kar Zubieta from University of Michigan have published a study which seems to show that placebos for pain actually cause your body to produce pain killers.
CBL
http://www.economist.com/displaystory.cfm?story_id=4316165THE placebo effect, long considered nothing more than psychological suggestibility, does now appear to be genuine. Researchers this week demonstrated that when a person is treated with a substance which he or she believes to have the power to relieve pain, the brain can be tricked into setting in motion some of that pain relief.
...
What he [Zubieta] found was that when the placebo was being administered—and the subjects were informed when it was—their brains released significantly more endorphins, the brain's natural painkillers. The researchers knew this because they had introduced a radioactive tracer that selectively binds to the same type of receptor in the brain, the mu-opioid variety, as the endorphins. More of the tracer was floating around unbound, suggesting the receptor sites were occupied by the endorphins. The work was published this week in the Journal of Neuroscience.
CBL