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Leukaemia - experimental treatment

Scientists used the gene-editing technique - previously only tested on mice - to create designer immune cells to hunt down the drug-resistant cancer.

Neat
 
My bro was diagnosed with liver/colon cancer this week. Maybe current treatments will keep him alive until this gets refined?
 
As a colon cancer survivor (15 years next May) and one who is constantly aware that it might bite me again, this is fantastic news.

Radiation treatments left me prone to another blood cancer, Multiple Myeloma. A treatment for leukemia may well transfer to treating MM as well.
 
JDH, have you had a genetic test? My bro's next step is to check for the gene for HNPCC. If he has the bad one, us siblings will need to be tested, and our offspring too. My interpretation of my own 23andMe test is that I am OK. Our oldest bro died of pancreas cancer too, which might be the same gene.

Looks like my sisters and I will need to get scoped more often. Except that the newest tech is an at home fecal swab that looks for cancer DNA. I guess if that is +, then you get the loong loong tailer.
 
JDH, have you had a genetic test? My bro's next step is to check for the gene for HNPCC. If he has the bad one, us siblings will need to be tested, and our offspring too. My interpretation of my own 23andMe test is that I am OK. Our oldest bro died of pancreas cancer too, which might be the same gene.

Looks like my sisters and I will need to get scoped more often. Except that the newest tech is an at home fecal swab that looks for cancer DNA. I guess if that is +, then you get the loong loong tailer.

No, no genetic test.
My mother had colon cancer and her father died of an impacted colon but there was no autopsy to look for why. (30 years ago).
My brothers have both had colonoscopies that were always clear.
Colonoscopy is still the gold standard , yes if fecal occult blood or cancer cell tests are positive then its time to take a video if the long pink wet tunnel.

I have Monoclonal Gammopathy of Unknown Significance - MGUS. A blood disorder that has some immune system products, immunoglobulins , that are nonfunctional clones of each other, which is very much like cancer.
Its not fully known how it develops but is in greater incidence in persons exposed to high levels of ionizing radiation.
I have a 1% chance per year of it going further and becoming MM or a form of leukemia.

Your bro has the advantage of advances that have occured since 2001 when I had surgery, chemo, and radiation.
 
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Your bro has the advantage of advances that have occurred since 2001 when I had surgery, chemo, and radiation.

The advantages of the gene test won't be his. It'll be for his living three siblings, 11 nieces and nephews, 14 grand N&Ns...

I'll wait for his result to get into cousins.

15 hears survivor? Colon only? His was already in his liver, they tested the cancer DNA, said it is colon cancer, so up went the scope. Yup.

I ought to try to find case histories of liver/colon for him. He is pretty fatalistic. If you can believe it, he said I'm the most up beat person he has talked to. He thought 6 months, like my other bro with pancreas cancer. Fastest liver prob I knew of is two years, and we had a friend make it several. He forgot those.
 
The advantages of the gene test won't be his. It'll be for his living three siblings, 11 nieces and nephews, 14 grand N&Ns...

I'll wait for his result to get into cousins.

15 hears survivor? Colon only? His was already in his liver, they tested the cancer DNA, said it is colon cancer, so up went the scope. Yup.

I ought to try to find case histories of liver/colon for him. He is pretty fatalistic. If you can believe it, he said I'm the most up beat person he has talked to. He thought 6 months, like my other bro with pancreas cancer. Fastest liver prob I knew of is two years, and we had a friend make it several. He forgot those.

Rectal actually, yes confined to that location. No invasion found in lymph node but had spread through the rectal wall. Lost my rectum and a lot of nearby bits & pieces just to be sure. I now lie on my back for colonoscopies, if you follow my drift.

Pancreas and liver are very different prognosis-wise.
 
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