As far as I have read, the possibilities for cosmology are fairly unconstrained by actual experimental data so almost anything you suggest might happen, but you'd need to be a physicist to answer in detail. So, I think all the science fiction favourites, such as white holes seeding new Universes or new universes coninuously bubbling into existence 'adjacent' to each other in different dimensions, cannot be excluded as impossible.
I think the only Universe that is completely precluded is one in which Kumar makes sense, but I could be wrong.