Another Nail in the Coffin for Vitamin Supplements

Puppycow

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Vitamins Found to Curb Exercise Benefits

If you exercise to improve your metabolism and prevent diabetes, you may want to avoid antioxidants like vitamins C and E.
. . .

Execpt for a couple of very specific cases, such as Folic acid for pregnant women, it seems like vitamin supplements are a big waste of money, and can actually have undesirable effects. Don't waste your money.
 
Vitamins Found to Curb Exercise Benefits



Execpt for a couple of very specific cases, such as Folic acid for pregnant women, it seems like vitamin supplements are a big waste of money, and can actually have undesirable effects. Don't waste your money.
I'm not a doctor by any means and have no training in health whatsoever, but this article seems very squirrelly. The actual cases where very certain types vitamins would have little to no, or even negative, impact, in very certain circumstances, seems limited to those engaging in considerable exercise and consuming significant volumes of these specific vitamins. The article agrees the conclusions may only apply to certain circumstances. And it even concludes with disagreement:

It certainly does not conclude that all “vitamin supplements are a big waste of money” or that all vitamins “can actually have undesirable effects” in all cases.

Andrew Shao of the Council for Responsible Nutrition, a trade association of dietary supplement makers, said the new study was well designed but was just one bit of evidence in a complex issue. Most available evidence points to the opposite conclusion, that antioxidants benefit health by reducing oxidative stress, he said.

“I wouldn’t change recommendations for anyone based on one study,” he said. “This is one small piece of the puzzle.”

I would tend to acknowledge the article’s conclusion statements:

“Most available evidence points to the opposite conclusion”
“I wouldn’t change recommendations for anyone”
 
A 5-seconds search in Pubmed with find lots of studies (including reviews) about vitamins C and E and their functions during exercise. In that light, I find titles like "Another Nail in the Coffin for Vitamin Supplements" indicative of little -if any- understanding of biochemistry and truly sad for a skeptical forum. Mind you, I'm not even urging anyone to actually open a couple of textbooks on sports nutrition or sports physiology and read the damn things. A simple search in the freely available indexing tool call pubmed is enough to show why such statements are not even worth-debunking.

ETA: I apologise for my tone; it's just that years of unfounded blanket anti-supplement statements on this forum have gotten the better of me.
 
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ETA: I apologise for my tone; it's just that years of unfounded blanket anti-supplement statements on this forum have gotten the better of me.


El Greco, can I ask if you use any vitamin supplements and what do you use them for?

Thanks,

Kuko
 
ETA: I apologise for my tone; it's just that years of unfounded blanket anti-supplement statements on this forum have gotten the better of me.

And what about the unfounded pro supplement advertisements that they out up?
 
While I suspect a good balanced diet likely provides pretty well all we need, I admit that I do not eat such a diet at home (I don't let anything green in my house as a rule. Bad luck. Particularly broccoli)- and at work I tend to get pasta, fried eggs and wieners as staples. (That's breakfast. You don't want to know about dinner).
So I take a multivitamin a day and a fish oil capsule. It may not do much good, but I doubt it does any harm.
I'm open to evidence though.
 
El Greco, can I ask if you use any vitamin supplements and what do you use them for?

Thanks,

Kuko


Sure. The standard ones are protein powder (for protein - duh) and EPA+DHA (for too many reasons). Most days I also take a multivitamin, especially on hypocaloric days since my diet those days rarely provides the RDA in all vitamins and minerals. When aerobic training is extended, I may take an electrolyte solution (Na, K, Cl, occasionally Mg and Ca). Depending on the frequency of the sessions and whether I need fast glycogen replenishment I may take glucose and/or maltodextrin post-exercise. When I was more interested in improving my times I also used to take NaHCO3+KHCO3. In the past I have used creatine monohydrate for its effects on strength, now I don't use it anymore because I have other training priorities. Sporadically I take Pygeum Africanum extract, not because I have any troubles with my prostate but rather because I predict I may in the future :D. I also take sporadically some antioxidants, usually cycling them (the opinions on antioxidant supplementation remain controversial but there is a boatload of different antioxidants and we are far from having examined all of their actions, so I follow a modest strategy). Sometimes I also supplement with fiber, when 1) I remember it and 2) I don't get enough with my diet.

In any case, I find it rather ...uhmmm... counter-intuitive when people accept that supplements CAN have bad side-effects but NOOOOO, they can't have any positive ones. It was fun what happened with ephedrine: As long as it was legal, many people said it was useless for fat loss, ignoring relevant studies that showed the opposite. When it was banned, they were all over it because it was dangerous :D (Personally I think that it is next to useless for fat loss, but for reasons that have nothing to do with metabolism). Not to mention that the line between drugs and supplements was, is and will remain very thin. E.g., fish oil used to be a supplement but now in many countries it is also a drug. So do others, like glucosamine, pine bark extract etc. Sometimes the exact same preparation is available both as drug and as supplement, e.g. several forms of iron. Especially with the current crisis, many national health systems will stop (or have already stopped) paying for certain drugs and will prefer to characterize them "supplements" so that patients will have to pay 100% of the price. Does iron proteinsuccinylate work better when it is a drug and worse when it is a supplement ?
 
There must be 1,000s of vitamins, minerals and other stuff we humans need, both known and unknown. Yet supplements only give us a handful of these. Work the rest out for yourself.
 
In any case, I find it rather ...uhmmm... counter-intuitive when people accept that supplements CAN have bad side-effects but NOOOOO, they can't have any positive ones.

It is my impression that people are opposed to claims that aren't evidence-based (which forms the bulk of the claims for supplements). And (as Puppycow pointed out) that those relatively few claims which are evidence-based don't justify a multi-billion dollar industry.

Not to mention that the line between drugs and supplements was, is and will remain very thin. E.g., fish oil used to be a supplement but now in many countries it is also a drug. So do others, like glucosamine, pine bark extract etc. Sometimes the exact same preparation is available both as drug and as supplement, e.g. several forms of iron. Especially with the current crisis, many national health systems will stop (or have already stopped) paying for certain drugs and will prefer to characterize them "supplements" so that patients will have to pay 100% of the price. Does iron proteinsuccinylate work better when it is a drug and worse when it is a supplement ?

This issue is not one of science, but of politics, and the consequence of successful lobbying. It's not rational.

Linda
 
It is my impression that people are opposed to claims that aren't evidence-based (which forms the bulk of the claims for supplements). And (as Puppycow pointed out) that those relatively few claims which are evidence-based don't justify a multi-billion dollar industry.

Is that your impression ? Then we have totally different impressions, because my impression is that people will buy anything that is cleverly marketed. Hence the "multi-billion dollar industry". They don't even have to explicitly make a claim, just an ad with a nice body and a nice background music will suffice.

I am also very well aware of the marketing strategies of pharmaceutical companies that produce "real" drugs. Strategies that have eg Orlistat prescribed to obese people without even examining their diet before, or antidepressants prescribed to people who don't even need them. Protein supplements and MRPs produced by companies with well-established fame among medical doctors, get prescribed almost exclusively to cover patients' protein needs, over better quality and cheaper proteins/ MRPs produced by supplement companies. But wait, don't pharmaceutical companies themselves often produce the same stuff as supplement companies and advertise them in the same way ? E.g., doesn't Bayer produce Redoxon Double Action (Vitamin C + Zinc) while directly or indirectly advertising it as a cure for common cold ? Lots of examples, yet you will rarely see "serious" pharmaceutical companies bashed over here for such products or such practices. And if supplements industry is "multi-billion dollar" one, then what is the pharmaceutical industry ?

In any case, this forum is supposedly populated not by ordinary people, but by people who examine everything based on the available evidence. In that light, blanket statements like "supplements are useless" are plain stupid. Period.

This issue is not one of science, but of politics, and the consequence of successful lobbying. It's not rational.

Exactly my point. No one is immune to money, and it is stupid to think that pharmaceutical companies and supplement companies (which many times are the same thing) are governed by different ethics.
 
Is that your impression ? Then we have totally different impressions, because my impression is that people will buy anything that is cleverly marketed. Hence the "multi-billion dollar industry". They don't even have to explicitly make a claim, just an ad with a nice body and a nice background music will suffice.

Clearly those people are not who you were talking about. You specifically made reference to people who make "unfounded blanket anti-supplement statements on this forum" and people that "accept that supplements CAN have bad side-effects but NOOOOO, they can't have any positive ones." I am pointing out that those people - the ones that you were specifically referring to - are really just criticizing claims that are not evidence-based, rather than making unfounded or counter-intuitive criticisms.

Lots of examples, yet you will rarely see "serious" pharmaceutical companies bashed over here for such products or such practices. And if supplements industry is "multi-billion dollar" one, then what is the pharmaceutical industry ?

What has this to do with the issue of supplements? I don't see anyone supporting non-evidence-based claims, regardless of whether they are coming from "serious" pharmaceutical companies or not. There's certainly plenty of criticism of less than ethical practices from any drug manufacturing source, on this forum.

In any case, this forum is supposedly populated not by ordinary people, but by people who examine everything based on the available evidence. In that light, blanket statements like "supplements are useless" are plain stupid. Period.

Did anyone say that? Perhaps your ire is unnecessary - it seems that what you are fighting is a strawman.

And in a way "supplements are useless", although that may be in a way that is specific to the drug approval requirements of certain countries, like the US. Supplements are defined in such a way as to carefully select out all those claims about drugs/vitamins/minerals that are not evidence-based and place them together under one umbrella. Once a claim is evidence-based, it tends to no longer be considered a supplemental claim, but rather an ordinary medical claim. Otherwise, there is nothing that distinguishes "supplements" from ordinary medicine.

Exactly my point. No one is immune to money, and it is stupid to think that pharmaceutical companies and supplement companies (which many times are the same thing) are governed by different ethics.

Did anyone say otherwise? What forces pharmaceutical companies to act ethically is that they have to provide evidence beforehand for their claims, and they have to know that their products are safe. Otherwise, one would assume that they would take the position enjoyed by manufacturers of supplements - they can say/do whatever they want until they get caught in a lie (without a systematic process for catching lies), and they don't have to know whether or not their products are safe.

Linda
 
Clearly those people are not who you were talking about. You specifically made reference to people who make "unfounded blanket anti-supplement statements on this forum" and people that "accept that supplements CAN have bad side-effects but NOOOOO, they can't have any positive ones." I am pointing out that those people - the ones that you were specifically referring to - are really just criticizing claims that are not evidence-based, rather than making unfounded or counter-intuitive criticisms.

Aaaah, you are talking about those people. And you are pointing out that they are NOT making blanket statements but instead criticizing claims. Then we must be reading different fora because I didn't bring claims into the discussion. Does the phrase "another nail in the coffin for vitamin supplements" sound like "criticizing claims" or like "blanket statement" to you ?

What has this to do with the issue of supplements? I don't see anyone supporting non-evidence-based claims, regardless of whether they are coming from "serious" pharmaceutical companies or not. There's certainly plenty of criticism of less than ethical practices from any drug manufacturing source, on this forum.

You don't see anyone supporting non-evidence-based claims ? How about NOT supporting evidence-based claims, like you just did here:

And in a way "supplements are useless", although that may be in a way that is specific to the drug approval requirements of certain countries, like the US. Supplements are defined in such a way as to carefully select out all those claims about drugs/vitamins/minerals that are not evidence-based and place them together under one umbrella. Once a claim is evidence-based, it tends to no longer be considered a supplemental claim, but rather an ordinary medical claim. Otherwise, there is nothing that distinguishes "supplements" from ordinary medicine.

Wrong. Protein supplements for example (a very big chunk of the "multi-billion dollar industry") are neither "useless" nor "drugs". Is there lack of evidence about the need for protein supplementation in very well described cases ? What about fish oil ? Is it useful when it's a drug for treating high triglycerides but when it is produced by a supplement company it's useless ? Do we have lack of evidence here ? What about creatine ? Is it useful or useless to athletes, even recreational ones ? Are you aware of relevant evidence or is it useless as well ? Are there special groups of people that need increased doses of certain minerals and/or vitamins that supplements can very well provide ? I can continue citing examples all day long as long as you are ready to show me how they are useless.

What do you call it when people keep repeating the mantra "supplements are useless" while closing their ears on the existing evidence to the opposite, happily singing "nah nah nah nah" ?

Did anyone say otherwise? What forces pharmaceutical companies to act ethically is that they have to provide evidence beforehand for their claims, and they have to know that their products are safe. Otherwise, one would assume that they would take the position enjoyed by manufacturers of supplements - they can say/do whatever they want until they get caught in a lie (without a systematic process for catching lies), and they don't have to know whether or not their products are safe.

I'm glad we agree on this one. AFAIK, in the US supplement producers are not allowed to make their claims on the package of the product. They have of course lots of other ways to spread their claims to the public. Pharmaceutical companies also have different channels to advertise. E.g. I happen to have in front of me an Eli-Lilly leaflet about Ceclor, with such nice descriptions and pictures that a supplement company would certainly be jealous of.
 
An interesting fact I just noticed and shows whether this forum is prejudiced against supplements or not: The blanket statements were not criticized. Instead, I was treated as if I endorsed all the claims supplements make (which I never did or even implied). On another forum I am known as the "anti-supplement guy" because I keep asking for evidence for the claims people believe. Here, I am treated as a supplement apologist just because I point out the damn facts. Opposite sides of the same unskeptical coin.
 
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ETA: I apologise for my tone; it's just that years of unfounded blanket anti-supplement statements on this forum have gotten the better of me.

I agree. There is a clear anti-supplement mentality within the medical community, which is reflected on this forum.
For example, there is solid scientific evidence that Vitamins B12 and D are not well absorbed by the elderly and deficiencies of these two vitamins often occur. Yet, physicians mostly neglect to advise the elderly in their care to consider supplementing with these two vitamins.
The historical bias against fish oil and the current prevailing lazy attitude concerning recommendations for fish oil is another case in point.
 
Aaaah, you are talking about those people. And you are pointing out that they are NOT making blanket statements but instead criticizing claims. Then we must be reading different fora because I didn't bring claims into the discussion.

When I say "claims", I mean the sorts of things you made specific reference to and which were the subject of the OP - vitamin C supplementation in exercise.

Does the phrase "another nail in the coffin for vitamin supplements" sound like "criticizing claims" or like "blanket statement" to you ?

Does it matter? The OP made specific reference to a specific claim and them made reference to evidence-based claims.

You don't see anyone supporting non-evidence-based claims ? How about NOT supporting evidence-based claims, like you just did here:

Can you give an example of an evidence-based claim that you don't think I supported?

Wrong. Protein supplements for example (a very big chunk of the "multi-billion dollar industry") are neither "useless" nor "drugs".

This is the issue. What the supplement industry has managed to do is to conflate 'food' and 'drugs'. Because there isn't really anything supplemental or non-evidence-based about meeting nutritional and metabolic requirements. Prior to the implementation of the Dietary Supplement Health and Education Act, drugs weren't treated as food. But creating a new category of 'supplements' allowed drugs to bypass normal safety and efficacy standards by relabeling themselves as food. But why bring up protein supplements? Why would it occur to you to call something that supplies essential nutrients "supplemental" in the first place, unless you are making claims that go beyond ordinary nutrition? Does it occur to us to call orange juice a 'supplement'?

Is there lack of evidence about the need for protein supplementation in very well described cases ? What about fish oil ? Is it useful when it's a drug for treating high triglycerides but when it is produced by a supplement company it's useless ? Do we have lack of evidence here ? What about creatine ? Is it useful or useless to athletes, even recreational ones ? Are you aware of relevant evidence or is it useless as well ? Are there special groups of people that need increased doses of certain minerals and/or vitamins that supplements can very well provide ? I can continue citing examples all day long as long as you are ready to show me how they are useless.

Actually, I'm more curious as to why you think they deserve a special category? Either you are talking about nutritional and metabolic needs, which make them food, or you are talking about altering the structure or function of the body, which makes them drugs.

Let's take fish oil as an example. If you are making structure/function claims, isn't it a drug? Niacin, when used in the treatment of high cholesterol, is considered a drug and treated as such. When it is provided as part of a balanced diet, it comes in/from food. When a pill form is used to correct a deficiency, it's part of normal medicine, not SCAM.

What about protein supplements - are you making essential nutrient claims or structure/function claims when you talk about protein supplements? If you are making structure/function claims, then how are they not a drug? If you are making essential nutrient claims, how is it not food? Give an example of the kind of claims you are making for protein supplements and of the evidence that you think supports those claims.

What do you call it when people keep repeating the mantra "supplements are useless" while closing their ears on the existing evidence to the opposite, happily singing "nah nah nah nah" ?

Because if there is evidence for structure/function claims, then they are simply drugs. The category 'supplements' exists only to hold those articles for which structure/function claims are made without the evidence we require of other drugs. The vitamin C that the OP was referring to wasn't being given in order to correct a deficiency, it was a structure/function claim about the effects of giving vitamin C in excess of nutritional requirements.

If the only thing that the supplement industry was about was supplying vitamins and minerals in pill form in order to correct deficiencies, or Ensure-like combinations of essential nutrients, I don't think there'd be anything for us to complain about. I certainly don't consider my use of iron pills in order to counteract my excessive losses Supplemental, Complementary and Alternative Medicine. It's the structure/function, drug-like claims that are made, without the safeguards against fraud and harm that lead to complaints.

I'm glad we agree on this one. AFAIK, in the US supplement producers are not allowed to make their claims on the package of the product. They have of course lots of other ways to spread their claims to the public. Pharmaceutical companies also have different channels to advertise. E.g. I happen to have in front of me an Eli-Lilly leaflet about Ceclor, with such nice descriptions and pictures that a supplement company would certainly be jealous of.

That's all they might be jealous of - they are in the enviable position of being able to say stuff that isn't true.

Linda
 
An interesting fact I just noticed and shows whether this forum is prejudiced against supplements or not: The blanket statements were not criticized.

The second post in this thread criticized the OP.

Instead, I was treated as if I endorsed all the claims supplements make (which I never did or even implied).

Where? I didn't see that from anyone here.

On another forum I am known as the "anti-supplement guy" because I keep asking for evidence for the claims people believe. Here, I am treated as a supplement apologist just because I point out the damn facts. Opposite sides of the same unskeptical coin.

Are you sure about that?

Linda
 
I agree. There is a clear anti-supplement mentality within the medical community, which is reflected on this forum.
For example, there is solid scientific evidence that Vitamins B12 and D are not well absorbed by the elderly and deficiencies of these two vitamins often occur. Yet, physicians mostly neglect to advise the elderly in their care to consider supplementing with these two vitamins.

Do you have any evidence for the claim in bold?

The historical bias against fish oil and the current prevailing lazy attitude concerning recommendations for fish oil is another case in point.

Or that?

Linda
 
I listen to a lot of Dr Radio (Sirius 114/XM 119) and I can tell you that the dermatologists in fact very strongly recommend Vitamin D supplements. They encourage testing vitamin D levels, and supplementing when needed. In fact, they strongly prefer Vitamin D supplements to sunlight (granted, these are dermatologists who face skin cancer every day)

The show last night (currently being replayed right now, in fact) had about 5 callers in a row discussing their prescribed vitamin D supplements.

So when it comes to Perpetual Student's claim, it seems to be mistaken at least for Vitamin D. The doctors on the show are advocates, and it is clear that listeners are getting them from their doctors.
 
fls, are you interested in intelligent discussion or just "winning this thread" ? Because if it is the latter, I will proclaim you winner and leave. We are talking about SUPPLEMENTS. Do you want me to dig up the FDA paper that describes what is a supplement and what isn't ? Do you want us to redefine what should be sold as supplement, what as drug and what as food ?

I am ready to prove that lots of what the FDA describes as supplements, are sold as supplements and are considered to be supplements by the vast majority of both medical professionals and laymen ARE NOT USELESS as you said:

And in a way "supplements are useless", although that may be in a way that is specific to the drug approval requirements of certain countries, like the US.

In fact I found this so outrageous (especially coming from a medical professional) that for a moment I thought about making it sig material.

But now we have what I believe is known in this neighbourhood as "moving the goalposts". You want to redefine what should be and what shouldn't be a supplement. "Why, fish oil is certainly useful but it is a drug!". "Protein ? Of course, but this is food!"

On what basis am I supposed to discuss if we don't even agree on what is a supplement and what isn't ? Perhaps your definition of "supplement" is "anything that is useless". If so, just tell me so that I'm not wasting my time.
 
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