HeyLeroy
Vegan Cannibal
- Joined
- Oct 14, 2005
- Messages
- 5,567
From the above-linked article:
Excuse me, but ... Gulf War syndrome?! Throwing that "disease" into the list brings this whole topic under suspicion.Hidden infections are now thought to be the basis of still other stubbornly elusive ills like chronic fatigue syndrome, Gulf War syndrome, multiple sclerosis, lupus, Parkinson's disease, and types of cancer.
Some of it is a bit out there; but misuse of antibiotic is a serious problem. In much of Oceana and East Asia, antibiotics are commonly available over the counter, and used as frequently as aspirin. New, highly-resistant strains of diseases though to be more or less dead are starting to crop up, thanks to the suppression of natural immune responses that turn the body into one big bacteria breeder. I dread to think what is likely to show up in the next 5 to 10 years because of that.Excuse me, but ... Gulf War syndrome?! Throwing that "disease" into the list brings this whole topic under suspicion.
Er, no. New, highly resistant strains are cropping up because of the selection pressure imposed on the organisms by indiscriminate use of antibiotics. Nothing to do with suppressing natural immune responses.
Rolfe.
Actually, the article exposed some interesting theories about how antibiotics might indeed affect the immune response. The scientists quoted were not claiming with certainty that it did, but I think they were investigating the question.
Specifically, the theories were about how our bodies might be harboring more benign bacteria than we'd previously suspected, and that by killing those bacteria as well as the malicious ones, antibiotics could have unforeseen adverse effects on our bodies, including possible effects on the immune system.Actually, the article exposed some interesting theories about how antibiotics might indeed affect the immune response.
Yes, it is. Using antibiotics indiscrimnately results in more bugs being exposed; but suppressing natural immune responses creates an ideal breeding ground for the bugs, allowing them more opportunity to develop a tolerance to specific antibiotics. Both conditions are important to the process. Non-immuno-suppressed people can harbour the germs, and impart resistances; but the germs do not develop quite as quickly, and it takes many generations of reproduction to develop a large enough base for them to be a serious threat. Under normal conditions, immuno-suppressed individuals -- such as the elderly -- don't survive long enough to pass along resistant bugs.Er, no. New, highly resistant strains are cropping up because of the selection pressure imposed on the organisms by indiscriminate use of antibiotics. Nothing to do with suppressing natural immune responses.
Rolfe.
Drug-induced immune hemolytic anemia occurs when certain drugs start an immune reaction against red blood cells. In some instances, the drugs interact with the red blood cell membrane, causing the cell to become antigenic. This means the body identifies these cells as not belonging to the body.
http://www.nlm.nih.gov/medlineplus/ency/article/000578.htm
In some cases, the level of resistance has forced a change to more expensive second or third-line agents. When resistance against these drugs also emerges, the world will run out of treatment options.
http://www.who.int/drugresistance/en/
We all agree that indiscriminate use of anitbiotics is a bad thing. However, you need to present evidence to back up the rest of your claims.Yes, it is. Using antibiotics indiscrimnately results in more bugs being exposed; but suppressing natural immune responses creates an ideal breeding ground for the bugs, allowing them more opportunity to develop a tolerance to specific antibiotics. Both conditions are important to the process. Non-immuno-suppressed people can harbour the germs, and impart resistances; but the germs do not develop quite as quickly, and it takes many generations of reproduction to develop a large enough base for them to be a serious threat. Under normal conditions, immuno-suppressed individuals -- such as the elderly -- don't survive long enough to pass along resistant bugs.
A short while ago, I found an interesting book written by a couple of epidemiologists who had spent quite a lot of time in the Far East, which made some disturbing predictions about future strains of supposedly dead diseases. I can't seen to find it at the moment, though (probably in storage with most of my books). According to the doctors who wrote the book, immuno-suppression is a natural result of indiscriminate over-use of antibiotics. Something which I've heard from a number of different sources.
We all agree that indiscriminate use of anitbiotics is a bad thing. However, you need to present evidence to back up the rest of your claims.
Oh, and Kumar: Your quotations do not support your position (as usual).
Hans
Still no support for your position.Mr Hans,
Then you can try here;
http://www.google.com/search?hl=en&ie=ISO-8859-1&q=drug+resistance&btnG=Google+Search
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Don't you know your own position? ..Can't say I'm really surprised.Which of my position?
There can be following thoughts on indiscriminate use of modern drugs:-
1. Creating Different resistant strain.
Correct. That is what we have been talking about.
2. Effect on our immune strength or immuno-suppressions.
Doubtful.
3. Side/adverse/toxic effects.
Certainly.
4. Cost & getting proper treatments.
Not really. Antibiotics are rather cheap. That is exactly the reason they are overused in ome places. And for proper treatment, well, for bacterial infections, antibiotics ARE the proper treatment.
5. If we/our cells becoming resistant/immune to drugs effects.
No, that is a misunderstanding. Our cells have ALWAYS been immune to the effects of antibiotics. Otherwise they would kill us, just like the bacteria. It is the bacteria that evolve immunity.
Still no support for your position.
Don't you know your own position? ..Can't say I'm really surprised.
Kumar, you have various opinions on medicine, health etc. You post a lot of references, but the references do not provide any support for your opinions. I suspect that you either don't actually read your references, or else you cannot understand them.Really I don't know/understand. Can you explain it in detail?
Well, this therad is about antibiotics, so I suggest you stay on topic.Thanks for the rest. By drug, I mean all modern medicines, not just antibiotics.
Weakness, yes. Suppression of immune system, no, that is a rare effect.Side/Adverse/toxic effects, if any drug can have, may cause some weakness to our body or immune system. Is it not correct?
In the terms of antibotics as a means of killing us unintentionally or intentionally is highly undoubtful, but it is possible in the most extreme simplicity of scientific mistakes. We know that viruses and bacteria evolve more advanced with each new threat to their existance, which in turn will force it to become something worse. If the antibodic forces the virus or bacteria to feel pressured under its affects, then the viruse or bacteria could adapt into something that could be worse or equivialent to that of HIV. Besides we only have a limited about of antibotics anyway, and each time we create one to kill something or fight against it, they viruses and bacteria adapt and mutate untill we reach a point where antibotics will be completely ineffective at all. Antibotics posses one other possible threat that you could consider important. if the Antibotic is engineered to fight against an illness in your body, what do you think happens if you White blood cells attack it and then attempt to break it down inside themselves. Your Antibotics give false impressions to your body that work like HIV to disable the bodies natural methods of expelling a illness (fever, coughing, etc) the result is that your body become dependant on that new antibotic to do the work, that is why they want you to resort to vacinnes and let your body heal the natural way. All it takes is for your cells to grow attached to the antibotic and thye could all together stop producing white blood cells and rely only on the antibotic.
Either way you look at it, your childrens' children's children will most likely be the genereation they have calculated for having the most problems with antibotic resistance by the viruses and bacteria. So in two more generations or so, this will not matter any how.
Kumar, you have various opinions on medicine, health etc. You post a lot of references, but the references do not provide any support for your opinions. I suspect that you either don't actually read your references, or else you cannot understand them.
No. It is because you haven't got a clue.Can it be due to my knowing & indicating some dynamic/different type of thinking on some still unclear conditions?
No. It is because you haven't got a clue.
Hans
One problem with your questions is that they are far too general. Forinstance the above. There is simply no straight answer to this. Some drugs can create dependence. Others can't. For instance, if you take laxatives every day, you will get constipated when you stop. And there are different kinds of dependence, too. You problem is that you want to pick out some statement and apply it universally, and that simply doesn't work.Ok, I shall try my best to just ask about my doubts in future. Will it be ok?
To start;
Can our body systems become drug dependance on regular use of modern durgs?
One problem with your questions is that they are far too general. Forinstance the above. There is simply no straight answer to this. Some drugs can create dependence. Others can't. For instance, if you take laxatives every day, you will get constipated when you stop. And there are different kinds of dependence, too. You problem is that you want to pick out some statement and apply it universally, and that simply doesn't work.
Our cells have ALWAYS been immune to the effects of antibiotics. Otherwise they would kill us, just like the bacteria. It is the bacteria that evolve immunity.
Hans
Originally Posted by MRC_Hans :
Our cells have ALWAYS been immune to the effects of antibiotics. Otherwise they would kill us, just like the bacteria. It is the bacteria that evolve immunity.
Point of correction: resistant/ce not immune/ity in both instances.
In antibiotic resistance it's not the patient that is resistant to the antibiotic. It's the bacteria infecting the patient that are resistant.How a first time user of any antibiotic can be resistant to the effects of that antibiotic? Many new antibiotics are introduced nowadays.
Yes. Eagle's eye.
In antibiotic resistance it's not the patient that is resistant to the antibiotic. It's the bacteria infecting the patient that are resistant.
How about you look up, oh I don't know... how antibiotics work? Cause you obviously have no clue.Do You mean to say that our body system or our cells accept antibiotic's exposure without any hesitance/resistance or adverse/toxic effect on them? How? They are also living entities?
How about you look up, oh I don't know... how antibiotics work? Cause you obviously have no clue.
How about you look up, oh I don't know... how antibiotics work? Cause you obviously have no clue.
Our cells have ALWAYS been immune to the effects of antibiotics. Otherwise they would kill us, just like the bacteria. It is the bacteria that evolve immunity.
Hans
BSM's post
Point of correction: resistant/ce not immune/ity in both instances.
Who is this "some"? Can I see a link?I know these are designed to work only on bacterias not on host. Why then some said, we or our cells are immune or resistant to antibiotics? I think better words will be that these are "ineffective" on our cells.
Who is this "some"? Can I see a link?
You think "ineffective" would be a better term? In this instance I'd prefer "resistant." In any case, as Mojo said, the issue is with bacteria developing resistance to antibiotics. If my pancreas cells get more resistant well, more power to them.I think it is there in my last post--may it be in that edited version. Pls re-read.
Guess.Btw, I noticed you are not able to read my edited posts(even immediately edited after initial posting), how?
That is the whole point of antibiotics. They kill bacteria but not the patient. To know this, you don't even need to find out how they work. All you need to do is look up the definition of the word "antibiotic" in a bloody dictionary!Do You mean to say that our body system or our cells accept antibiotic's exposure without any hesitance/resistance or adverse/toxic effect on them? How? They are also living entities?