Might we one day preferentially put orbiting observatories that will require multiple servicing missions in lunar orbit instead in order to take advantage of the lower delta-v required to get from the lunar surface to the platform? Granted we would need a pretty sophisticated lunar surface presence to do so.
Very sophisticated. Otherwise, those parts and crew are coming from Earth, and there's no reason to make a stop on the Moon. I don't see this happening for a long, long time.
Being on the moon makes some problems of pointing much easier for a telescope.
Some, but it brings new problems. If you're going to do large scale assembly this is arguably easier in gravity, even Lunar gravity. The Moon is also nice and quiet with respect to radio frequencies. One can put the collector on the far side and never see the Earth.
On the other hand, the Moon is a severely challenging dust and thermal environment, probably enough to outweigh any possible advantages. Thermally the Moon sees fourteen days of blazing sun, followed by fourteen days of total darkness, and the temperature swings are on the order of 250oC! The thermal problem can be partly mitigated by building in a permanent shadow crater on one of the poles, especially if imaging in LWIR or radio where low temperature is a good thing, but doing this will limit your field of view to practically nothing.
Moral of the story, most deep space science and observatories will be better served in space. The science reasons to be on the Moon all have to do with the Moon itself or what we can find there.
Since the ISS is a waste of time and money (wherever it is), your "intellectual exercise" begets the question of why not pitch it into the Pacific Ocean, or somewhat more safely, into deep space.
Politics forum is that way, sir.
Incidentally, the problem of deorbiting the ISS is a big one.
