ETR depends on the size of genome and mutation rate used in ev. For example, Dr Schneider used a genome length of 256 and a mutation rate of 1 mutation per 256 base per generations and estimated a rate of information increase of 1 bit per 11 generations. He then extrapolated this value to a human genome and estimated 1 billion years (with conditions). If you use a mutation rate of 1 mutation per 1,000,000 bases with a genome length of 256 bases, the rate of information accumulation drops to about 1 bit per 4000 generations and the amount of time required to evolve a human genome becomes about 4 trillion years.
If you use longer genomes in the ev model, the rate of information accumulation drops markedly. In fact, the largest genome either Paul or I have run is about 100k and the rate of information accumulation is at least 10’s of thousands of times slower than for the 256 base case. If you are depending on random point mutations and natural selection to account for the divergence of humans and chimps (gigabase genomes), ev shows this is mathematically impossible. For bacteria, you might make a rough estimate that the simples bacterial genome has about 1,000,000 bits of information. Ev is showing for a 100k genome that information can be gained at the rate of about 1 bit per million generations. Therefore, it would take 10^6 * 10^6 = 10^12 generations to accumulate the information to evolve a 500k genome. If you assume 1 generation per day that gives a required time of about 2.7 billion years to evolve a 500k bacterial genome by random point mutations. There is a really big if in this calculation. That big if is what is the selection process that would allow for evolution of the 200+ genes de novo. Dr Schneider’s selection process allows for the de novo evolution of binding sites because it allows step wise recognition of the sites. There is no real selection process that can be demonstrated that works like this. With Dr Schneider’s model, you would have to assume that there are hundreds of different selection processes that somehow can evolve the many different genes required for even the simplest life form. So the 2.7 billion year estimate for the evolution of a bacterial genome is an extremely overoptimistic estimate based on an unrealistic selection process.
The real problem that you evolutionarians have is not that ev doesn’t include all the different forms of mutations, it is in defining a realistic selection process that evolve genes de novo. There is/are no such selection process(s).