Merged 2019-nCoV / Corona virus

Status
Not open for further replies.
Skeptical Greg said:
I would have to look closer at the review and see who sponsored it.

These things don't get done without grants.

This particular review may be benign, but it's interesting that the first cite had the opposite conclusion that SG was claiming.

P.S.

Here is more from the conclusions of the review SG cited..



So, according to the review, fever reducing drugs are not considered a first line of treatment.
Click to expand...

I think you are reading more into your hilighted sentence than it actually says. There is a big difference between first line care and urgent care. It is also very general statement that gives no indication of exactly who, and under what circumstances, the drugs are not considered to be first line care. I stand to be corrected but I think that in actual current medical practice the administration of such drugs is often first line care for non critical situations. A small number of people who present with Covid 19 are actually critical or even urgent.
 
Steve said:
I stand to be corrected but I think that in actual current medical practice the administration of such drugs is often first line care for non critical situations....
Click to expand...

It probably is, but we have already shown there is no known benefit to lowering non critical fevers..

Fever in a not critical situation is a symptom, lowering it does nothing to address the cause.

It's like when you are given a drug for inflammation, but nothing is done to address the cause of the inflammation.
 
Skeptical Greg said:
It probably is, but we have already shown there is no known benefit to lowering non critical fevers..

Fever in a not critical situation is a symptom, lowering it does nothing to address the cause.

It's like when you are given a drug for inflammation, but nothing is done to address the cause of the inflammation.
Click to expand...

It depends on how high the fever is.
 
Skeptical Greg said:
It probably is, but we have already shown there is no known benefit to lowering non critical fevers..

Fever in a not critical situation is a symptom, lowering it does nothing to address the cause.

It's like when you are given a drug for inflammation, but nothing is done to address the cause of the inflammation.
Click to expand...

If you lower a non critical fever and prevent it from increasing you may prevent a critical temperature from ever being reached. Once the immediate potential of an increasing fever (or inflammation) is alleviated medical personnel can proceed to treat the underlying cause in a more methodical manner.
 
Skeptical Greg said:
Here are the results of the study which was number one on your list.

Association of body temperature and antipyretic treatments with mortality of critically ill patients with and without sepsis: multi-centered prospective observational study.

You want me to find the next one?
Click to expand...
Please do. And try reading the article and my post where I said:
Only in sepsis was fever found to have any benefit in fighting the pathogen.
Click to expand...

Don't you think it would be more productive to try to learn something than to try to win this pissing contest?
 
Steve said:
If you lower a non critical fever and prevent it from increasing you may prevent a critical temperature from ever being reached. Once the immediate potential of an increasing fever (or inflammation) is alleviated medical personnel can proceed to treat the underlying cause in a more methodical manner.
Click to expand...


Fever and the thermal regulation of immunity: the immune system feels the heat

The fever response is executed by integrated physiological and neuronal circuitry and confers a survival benefit during infection.
Click to expand...

A long article, but I see nothing about the benefits of lowering fever, under normal circumstances of infection & etc.


I am not talking about the need to lower body temp in critical situations.
 
Last edited:
William Parcher said:
CNN: New Zealand reports second case.
Click to expand...

Ninja'd on that sorry - I posted how she's been flying around the country non-stop in the few days prior.
______________________

Big numbers coming out of S Korea, Iran & Italy. Looks like a runanway train.

I take issue with Bloomberg's screaming headline saying the death rate is 3.8%, though. There's no doubt that we're not seeing a huge number of cases, and South Korea, with mass testing and rigorous treatment, is the best guide.

They're showing a fatality rate of 0.6%, and at the rate they're finding infections, I'd say they're still missing probably half of cases where the disease is so mild as to be seen as irrelevant and not tested. We know from USA that it's been in the country for weeks prior to the non-Diamond Princess deaths.
 
CNN: "The patient is a New Zealand citizen in her 30s who recently returned to Auckland from northern Italy, the statement said. She does not require hospital level care and is currently under self-isolation at home."

There would seem to be some probability that she infected people which would cause it to now be on the loose in NZ.
 
Skeptical Greg said:
I would have to look closer at the review and see who sponsored it.

These things don't get done without grants.

This particular review may be benign, but it's interesting that the first cite had the opposite conclusion that SG was claiming.
Click to expand...

Answer:
Authors’ contributions
EJW and MC contributed to the literature review and the drafting of the manuscript. Both authors read and approved the final manuscript.

Authors’ information
EJW has an interest in pre-hospital and ICU hyperthermia, and has provided medical cover for major sporting and public events. He is lead author of the FSEM UK heatstroke consensus guidelines, and has also published and spoken internationally in this area.
Click to expand...
I'm not sure which sponsors you think have an interest.



Skeptical Greg said:
So, according to the review, fever reducing drugs are not considered a first line of treatment.
Click to expand...
So? How is that relevant to the discussion?

In the ICU when someone has a dangerously elevated temperature we use mechanical cooling because drugs don't act fast enough.

You're not helping your case pulling a sentence out here and there.
 
Last edited:
The WHO Situation Reports seem increasingly useless.

It shows two new cases in the United States today, with no deaths, while nine deaths are in the headlines in Washington, with confirmed cases in lots of states in the last couple of days.
 
Meadmaker said:
The WHO Situation Reports seem increasingly useless.

It shows two new cases in the United States today, with no deaths, while nine deaths are in the headlines in Washington, with confirmed cases in lots of states in the last couple of days.
Click to expand...

Unless the US reports its numbers to the WHO, or let's their experts on the ground, it can't get accurate numbers. And we know that this administration isn't interested in getting accurate numbers.
 
Status
Not open for further replies.

Back
Top Bottom