That too.
But they can't de-nuke the nominations. Rules can only be changed at the beginning of the Senate session.
No telling what scheming McConnell could try though.
That is
one way to change the rules
by majority vote. The rules can be changed any time, but most methods require 3/5s or 2/3s support, so trying to change a cloture rule when faced with a Senate blocking a cloture vote is obviously not going to happen.
This is where they got creative. When the presiding officer makes a ruling from the chair, that ruling can be appealed. That ruling is upheld or overturned by majority vote.
A very simple version:
Majority Leader: I don't care that cloture failed, we're moving forward.
Presiding Officer: Uh, no, you can't do that.
ML: I appeal your decision.
PO: uh-oh.
ML: I win.
PO: It does appear so.
Basically this is taken as a new precedent because the majority just demonstrated they can do it whenever they want, so let's not make it require an entire roll call to settle the same question next time.
ETA: It's been a while since I waded into this, but that whole issue may only apply to the full floor consideration. I'm not familiar enough with the rules of the Judiciary Committee to know if the Ds have leverage to stall it there, instead.